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ZOE Science & Nutrition

ZOE Science & Nutrition

ZOE

The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.

131 - Menstruation: Science, medicine and mythology
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  • 131 - Menstruation: Science, medicine and mythology

    Periods are taboo! Despite the fact that half of the world’s population experience them. This taboo has led to countless myths around the topic. “The internet’s gynecologist” Dr. Jen Gunter is here to usher in a new era where people understand – and can advocate for – what they need as their body changes each cycle.

    Jonathan is joined by Dr Sarah Berry and Dr Jen Gunter to get a better understanding of our body's behavior during the menstrual cycle. Jen will provide you with her period toolkit and offer solutions to the most common problems of modern-day period health.

    Dr. Jen Gunter is a gynecologist and pain medicine physician at the Permanente Medical Group in northern California. Her books ‘The Vagina Bible’ and ‘The Menopause Manifesto’ were both New York Times bestsellers. Her 2024 book ‘Blood’ tackles the science, medicine and mythology of menstruation.

    Learn how your body responds to food. Take our FREE quiz and get 10% off here.

    Follow ZOE on Instagram.

    Timecodes:

    00:00 Introduction

    01:26 Quickfire questions

    02:31 Shame culture around menstruation

    04:20 The evolution and purpose of the menstrual cycle

    06:30 Menstrual cycle mechanics

    11:08 Understanding heavy periods and iron deficiency

    14:01 Addressing period pain and discomfort

    21:39 Diet, appetite, and periods: what's the connection?

    26:09 Understanding PMS and PMDD

    27:55 PMS causes and symptoms

    30:52 Treatment options for PMS and PMDD

    31:51 Demystifying polycystic ovarian syndrome (PCOS)

    35:42 The role of diet and obesity in PCOS

    37:32 Advice for managing PMS

    40:19 Menstrual cramps and pain management

    47:08 Iron supplementation strategies

    📚 Dr. Jen Gunter’s books:

    The Menopause ManifestoBlood: The Science, Medicine, and Mythology of Menstruation

    📚 Books from our ZOE Scientists:

    Every Body Should Know This by Dr Federica AmatiRecipes for a Better Menopause by Dr Federica AmatiFood For Life by Prof. Tim Spector

    Studies related to today’s episode:

    Prevalence of Iron Deficiency and Iron-Deficiency Anemia in US Females Aged 12-21 Years, 2003-2020, from the Journal of the American Medical AssociationThe Role of Estrogen in Insulin Resistance: A Review of Clinical and Preclinical Data, from The American Journal of Pathology

    Have feedback or a topic you'd like us to cover? Let us know here

    Episode transcripts are available here.

    Thu, 30 May 2024 - 55min
  • 130 - Why dementia could start in your blood vessels with Dr. William Li

    55 million people suffer dementia worldwide with numbers expected to double every 20 years. Understanding the link between our heart health and brain function is critical, illuminating the profound impact that heart health has on preventing dementia.

    Dr. William Li, an expert in cardiovascular and metabolic health. He reveals how caring for our heart is not just about longevity but maintaining sharp, effective brain function as we age. His groundbreaking work has impacted more than seventy diseases including diabetes, heart disease, and obesity. Dr. Li is also a New York Times best-selling author.

    In today’s episode, Dr. Li explains how simple lifestyle choices in diet, exercise and sleep can drastically shape our brain's health and stave off dementia.

    If you want to uncover the right foods for yourbody, head to zoe.com/podcast, and get 10% off your membership.

    Follow ZOE on Instagram

    Timecodes

    00:00 Introduction

    01:23 Quickfire questions

    03:30 Understanding dementia and Alzheimer's disease

    04:50 Dementia versus ageing

    06:35 The role of blood vessels in brain health

    07:55 How circulation affects brain function

    09:23 What causes blood clots and strokes?

    11:06 The importance of maintaining healthy blood vessels

    12:15 The impact of lifestyle choices on brain health

    15:01 What happens in our brains when we sleep?

    19:35 What is the glymphatic system?

    22:40 Vascular dementia may be the most common form of dementia

    24:35 The role of glucose in brain function

    27:10 What causes dementia and why does it happen when we get older?

    29:00 Preventing dementia with lifestyle changes

    31:10 What are healthy blood vessels like?

    37:50 The surprising role of EPCs in brain repair

    41:30 Can you slow down or reverse dementia?

    52:08 The connection between gut health and brain health

    51:40 The importance of exercise for brain health

    56:30 How to avoid dementia

    01:01:16 The link between mental health and cardiovascular disease

    📚 Dr. William Li’s books:

    Eat to Beat Disease Eat to Beat Your Diet

    📚 Books from our ZOE Scientists:

    Every Body Should Know This by Dr Federica AmatiFood For Life by Prof. Tim Spector

    Relevant studies:

    A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk, published in NatureHeart-brain connections: Phenotypic and genetic insights from magnetic resonance images, published in ScienceCocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study—a randomized controlled trial, published in The American Journal of Clinical Nutrition

    Have feedback or a topic you'd like us to cover? Let us know here

    Episode transcripts are available here.

    Thu, 23 May 2024 - 1h 13min
  • 129 - How inflammation could age you with Prof. Philip Calder

    Inflammation is a complicated topic. Short-term inflammation plays an essential role in fighting infections and healing injuries. But too much inflammation can be a catalyst for chronic ailments, like heart disease, type 2 diabetes, autoimmune disorders, rheumatoid arthritis, and obesity.

    What we eat can influence our inflammatory responses and contribute to chronic, low-grade inflammation.

    In today’s episode, Prof. Philip Calder helps us understand the science behind inflammation, how it impacts our health and what food has to do with it.

    Philip is head of the School of Human Development and Health, as well as a Professor of Nutritional Immunology, in the Faculty of Medicine at the University of Southampton. He’s also an internationally recognised researcher on the metabolism and functionality of fatty acids. His work focuses on the roles of omega-3 fatty acids and the influence of diet and nutrients on immune and inflammatory responses. 

    If you want to uncover the right foods for yourbody, head to zoe.com/podcast, and get 10% off your membership.

    Follow ZOE on Instagram.

    Timecodes

    00:00 Introduction

    01:20 Quickfire questions

    02:55 The role of inflammation in immunity

    05:30 Chronic inflammation and disease

    08:30 How to measure inflammation

    09:53 Low-grade inflammation and disease risk

    12:30 What causes blood vessel inflammation?

    15:23 What creates the narrowing of blood vessels?

    17:20 How inflammation can cause blood clots, heart attacks and strokes

    19:15 Inflammation and aging

    21:40 Inflammation and lifestyle factors

    25:07 Obesity and inflammation

    28:45 Muscle loss and inflammation (sarcopenia)

    30:52 The impact of meals, sugar and fats on inflammation

    33:35 How diet could reduce inflammation

    34:42 Why we all respond to food differently

    38:42 Dietary choices to manage inflammation

    40:00 What are omega-3s?

    41:17 Anti-inflammatory foods

    43:40 Health benefits of omega-3 fatty acids

    45:55 Challenges with farmed salmon

    📚 Books from our ZOE Scientists:

    Every Body Should Know This by Dr Federica AmatiFood For Life by Prof. Tim Spector

    Mentioned in today's episode:

    Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology? in the British Journal of Clinical Pharmacology

    Omega-6 fatty acids and inflammation in PLEFA

    Omega-3 fatty acids and inflammatory processes in Nutrients 

    Another relevant study:

    Health relevance of the modification of low-grade inflammation in ageing and the role of nutrition in Ageing Research Reviews

    Have feedback or a topic you'd like us to cover? Let us know here

    Episode transcripts are available here.

    Thu, 16 May 2024 - 1h 00min
  • 128 - Your new menopause toolkit with Dr. Mary Claire Haver & Dr. Sarah Berry

    The menopause transition can bring unexpected challenges — the effects can significantly impact daily life and long-term health.

    Dr. Mary Claire Haver is a board-certified gynaecologist and a menopause specialist. She's helped thousands of women in perimenopause and menopause to realise their health goals. In today’s episode, she joins Jonathan and ZOE's Chief Scientist Dr. Sarah Berry to shed light on what to expect during these life stages.

    Sarah and Mary Claire describe practical strategies for managing symptoms, critical conversations to have with healthcare providers, and how to advocate for yourself effectively in medical settings.

    Follow Mary Claire on Instagram.

    If you want to uncover the right foods for yourbody, head to zoe.com/podcast, and get 10% off your membership.

    Follow ZOE on Instagram

    Timecodes:

    00:00 Introduction

    01:33 Quickfire questions

    05:53 There is a lack of menopause training in medical school

    07:02 Most women are going into menopause blind

    07:43 Why menopause symptoms vary

    09:30 The hormonal ‘zone of chaos’

    11:45 ZOE PREDICT data on menopause symptoms

    13:36 How long do perimenopause symptoms last?

    17:52 Perimenopause at age 35?

    18:34 Why hormone tests are worthless

    20:53 The risk of chronic disease after menopause

    24:53 Why does menopause increase hunger?

    28:39 Why medicine and research is male-dominated

    32:34 How to talk to your doctor about menopaue

    34:12 Pregnancy research - 10x more extensive than menopause research!

    35:14 Mary Claire’s toolkit of strategies for menopause

    36:34 What are the long-term health benefits of hormone replacement therapy?

    38:36 Is HRT safe for most women?

    42:47 Brand new ZOE study results: diet and menopause

    49:16 Top 3 tips to help with symptoms

    54:34 What is ‘frozen shoulder’ and how can you treat it?

    📚 Mary Claire's book

    The New Menopause

    📚 Books from our ZOE Scientists

    Every Body Should Know This by Dr Federica AmatiFood For Life by Prof. Tim Spector

    Mentioned in today's episode

    Menopause transition and cardiovascular disease risk: Implications for timing of early prevention: A scientific statement from the American Heart Association in CirculationThe controversial history of hormone replacement therapy in MedicinaDr. Vonda Wright’s website

    Have feedback or a topic you'd like us to cover? Let us know here

    Episode transcripts are available here.

    Thu, 09 May 2024 - 1h 08min
  • 127 - The medicines hiding in your spice rack with Kanchan Koya & Dr. Sarah Berry

    In today’s episode we’re uncovering the medicines hiding in your kitchen. 

    Molecular biologist Kanchan Koya joins Jonathan and Sarah to explore the incredible health benefits of spices. From controlling blood sugar to soothing a sore throat, we’ll discover what the latest research says about household favorites including ginger, cinnamon and cloves. 

    Kanchan Koya is a food scientist, founder of the spice-centric food blog Chief Spice Mama and author of the cookbook ‘100 Recipes with Healing Spices for Your Family Table’. She will show us how to get the most out of spices, with simple cooking tips and delicious recipes. 

    Want to make Kanchan’s show stopper spice dish? Find the recipe here.

    Follow Kanchan on Instagram.

    If you want to uncover the right foods for yourbody, head to zoe.com/podcast, and get 10% off your membership.

    Follow ZOE on Instagram.

    Timecodes:

    00:00 Introduction

    01:26 Quickfire questions

    03:08 What are spices?

    03:43 Polyphenols in spices

    07:25 Spices and your health

    11:01 Cinnamon and blood sugar control

    14:49 Anti-inflammatory benefits of spices

    21:08 A practical guide to using spices

    31:40 Reviving old spices

    33:11 The wonders of ginger: from morning sickness to gut health

    35:56 Spiced cooking tips

    37:41 Breakfast ideas: add spices to start your day

    39:44 Simple spicy snacks

    42:05 Dinner delights: spicing up main meals

    44:11 Spices for kids

    46:24 Spiced drinks: from chai to golden milk

    48:24 The ultimate spice dish

    Studies related to today’s episode:

    Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study published in TrialsAnalgesic effect of the aqueous and ethanolic extracts of clove,published inAvicenna Journal of PhytomedicineEffect of cinnamon spice on continuously monitored glycemic response in adults with prediabetespublished inThe American Journal of Clinical NutritionStar anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance published in Phytotherapy ResearchGinger-Mechanism of action in chemotherapy-induced nausea and vomiting, published by Critical Reviews in Food Science and Nutrition

    Have feedback or a topic you'd like us to cover? Let us know here

    Episode transcripts are available here.

    Thu, 02 May 2024 - 59min
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