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Diabetes Care “On Air” is the monthly podcast of the American Diabetes Association’s premier clinical research journal, Diabetes Care. In each episode, co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, interview key authors of editor-selected feature articles and discuss the latest research presented in Diabetes Care. The podcast is intended for diabetes researchers and specialists, endocrinologists, and other health care professionals. Join Alice and Mike as they explore the latest high-impact research and information on diabetes care, treatment, and prevention. To learn more about Diabetes Care, please visit https://diabetesjournals.org/care.
- 26 - Diabetes and driving, GLP-1 medicines for type 2 diabetes and obesity, and more!
Welcome to episode no. 26 (November 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the November 2024 issue of Diabetes Care and beyond.
0:40 In the spirit of Thanksgiving, Alice and Mike begin with a special offer from the ADA for new and renewing members: a 15% discount on a 1- or 2-year membership. Go to professional.diabetes.org/membership, create your account, fill out the application, and use the discount code ‘FALL24’ at checkout. Act fast because this offer expires November 30, 2024!
3:00 In a Diabetes Care “On Air” first, Michael interviews not a clinician, but a lawyer. Anthony May, a law partner at Brown, Goldstein, and Levy, LLP in Baltimore, MD, is the senior author of “Diabetes and Driving: A Statement of the American Diabetes Association.” This statement provides an overview of existing licensing rules for people with diabetes in the U.S., addresses the factors that affect driving ability, identifies general guidelines for assessing driver fitness and determining appropriately tailored licensing restrictions, and provides practical guidance for health care professionals regarding clinical interventions and education for people with diabetes. This review is available for free at doi.org/10.2337/dci24-0068.
16:15 Amy is joined by Dr. Daniel J. Drucker, endocrinologist and professor of medicine at the Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, and one of Time Magazine’s 100 most influential people of 2024. They discuss his review, “Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity.” This article is available for free at doi.org/10.2337/dci24-0003.
30:45 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the October 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Retnakaran et al. A Glycemic Threshold Above Which the Improvement of β-Cell Function and Glycemia in Response to Insulin Therapy Is Amplified in Early Type 2 Diabetes: The Reversal of Glucotoxicity doi.org/10.2337/dc24-1375 Yang et al. Maternal Glycemia During Pregnancy and Child Lung Function: A Prospective Cohort Study doi.org/10.2337/dc24-0865 Lim et al. Utilizing Continuous Glucose Monitoring for Early Detection of Gestational Diabetes and Pregnancy Outcomes in an Asian Population doi.org/10.2337/dc24-0944 Agarwal et al. The Supporting Emerging Adults With Diabetes (SEAD) Program: An Adult-Based Real-World Clinical Model That Improves Hospitalizations, Diabetes Technology Uptake, and Glycemic Outcomes in Underserved Young Adults With Type 1 Diabetes doi.org/10.2337/dc24-1346 Beunen et al. Advanced Hybrid Closed-Loop Therapy Compared With Standard Insulin Therapy Intrapartum and Early Postpartum in Women With Type 1 Diabetes: A Secondary Observational Analysis From the CRISTAL Randomized Controlled Trial doi.org/10.2337/dc24-1320 Htoo et al. Health Care Utilization and Costs Associated With Empagliflozin in Older Adults With Type 2 Diabetes doi.org/10.2337/dc24-0270To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 01 Nov 2024 - 44min - 25 - Preserving muscle mass with antiobesity medications, investigating the relationship between sensor-detected hypoglycemia and patient-reported hypoglycemia, and more!
Welcome to episode no. 25 (October 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the October 2024 issue of Diabetes Care and beyond.
0:40 Alice and Mike ring in Fall with a special offer from the ADA for new and renewing members: a 15% discount on a 1- or 2-year membership. Go to professional.diabetes.org/membership, create your account, fill out the application, and use the discount code ‘FALL24’ at checkout. Act fast because this offer expires November 30, 2024!
3:55 Alice interviews Dr. Bu B. Yeap, an endocrinologist and professor in the medical school at University of Western Australia in Perth, Australia. He is a corresponding author of “Incretin-Based Weight Loss Pharmacotherapy: Can Resistance Exercise Optimize Changes in Body Composition?” a narrative review which highlights the degree to which new antiobesity medications cause loss of lean mass, and the importance of resistance exercise in preserving muscle. The review is available at doi.org/10.2337/dci23-0100.
16:45 Mike welcomes Dr. Patrick Divilly, lead author of “Relationship Between Sensor-Detected Hypoglycemia and Patient-Reported Hypoglycemia in People With Type 1 and Insulin-Treated Type 2 Diabetes: The Hypo-METRICS Study.” This study is available at doi.org/10.2337/dc23-2332.
31:55 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the October 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Ye et al. Large-Scale Proteomics Improve Prediction of Chronic Kidney Disease in People With Diabetes. doi.org/10.2337/dc24-0290 Borel et al. Closed-Loop Insulin Therapy for People With Type 2 Diabetes Treated With an Insulin Pump: A 12-Week Multicenter, Open-Label Randomized, Controlled, Crossover Trial. doi.org/10.2337/dc24-0623 Atta et al. Associations of High BMI and Excessive Gestational Weight Gain With Pregnancy Outcomes in Women With Type 1 Diabetes: A Systematic Review and Meta-analysis doi.org/10.2337/dc24-0725 Yeh Lee et al. Empowering Hospitalized Patients With Diabetes: Implementation of a Hospital-wide CGM Policy With EHR-Integrated Validation for Dosing Insulin doi.org/10.2337/dc24-0626 Huang et al. Comprehensive Multiple Risk Factor Control in Type 2 Diabetes to Mitigate Heart Failure Risk: Insights From a Prospective Cohort Study doi.org/10.2337/dc24-0864 Dove et al. Diabetes, Prediabetes, and Brain Aging: The Role of Healthy Lifestyle https://doi.org/10.2337/dc24-0860To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 11 Oct 2024 - 45min - 24 - A celebration of the 40th anniversary of the DCCT/EDIC! Hear interviews of key figures of DCCT/EDIC past and present, including its most important participants: individuals living with diabetes.
Welcome to episode no. 24 (September 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the September 2024 issue of Diabetes Care and beyond.
0:30 Alice and Mike begin by highlighting a special section of the September issue of Diabetes Care: the DCCT/EDIC 40th Anniversary Collection. This collection contains five original articles containing new research from DCCT/EDIC as well as a commentary and review on the history and importance of the DCCT/EDIC. This episode of Diabetes Care “On Air” features several of the researchers who have been involved in DCCT/EDIC as well as some of the individuals living with diabetes who have taken part in the studies. This article collection can be accessed at https://diabetesjournals.org/collection/2296/DCCT-EDIC-40th-Anniversary-Collection.
1:26: Alice kicks off the interviews by bringing on four individuals who she refers to as “very special guests”: Dr. Rose Gubitosi-Klug, Gayle Lorenzi, Pamela Curtin, and Bill King. Dr. Klug is the current chair of the DCCT/EDIC Research Group, and Gayle Lorenzi is the chair of the DCCT/EDIC Coordinators Committee and Community Health Project manager. Pamela Curtin and Bill King, as Alice says, “Represent arguably the most important people for this entire project.” They are individuals with diabetes who have participated in the study and have given their time, bodies, and minds to the pursuit of science and better care.
46:33: Mike talks to some of the authors of the five original articles of the DCCT/EDIC 40th anniversary collection that are featured in September’s issue: Drs. Barbara A. Blodi, Christine P. Limonte, Rodica Pop-Busui, and Naina Sinha Gregory. The articles can be accessed at https://diabetesjournals.org/collection/2296/DCCT-EDIC-40th-Anniversary-Collection.
1:22:03: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the September 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Yland et al. Perinatal Outcomes Associated With Metformin Use During Pregnancy in Women With Pregestational Type 2 Diabetes Mellitus. https://doi.org/10.2337/dc23-2056 Feig et al. Long-term Neurobehavioral and Metabolic Outcomes in Offspring of Mothers With Diabetes During Pregnancy: A Large, Population-Based Cohort Study in Ontario, Canada. https://doi.org/10.2337/dc24-0108 Bjornstad et al. Dulaglutide and Glomerular Hyperfiltration, Proteinuria, and Albuminuria in Youth With Type 2 Diabetes: Post Hoc Analysis of the AWARD-PEDS Study. https://doi.org/10.2337/dc24-0322 Johansson et al. Rational Pharmacotherapy in Type 2 Diabetes: Danish Data From 2002 to 2020 on Mortality, Diabetes-Related Outcomes, Adverse Events, and Medication Expenses. https://doi.org/10.2337/dc24-0619 Bismuth et al. Sustained 3-Year Improvement of Glucose Control With Hybrid Closed Loop in Children With Type 1 Diabetes While Going Through Puberty. https://doi.org/10.2337/dc24-0916 Kianersi et al. Association Between Accelerometer-Measured Irregular Sleep Duration and Type 2 Diabetes Risk: A Prospective Cohort Study in the UK Biobank. https://doi.org/10.2337/dc24-0213To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Thu, 05 Sep 2024 - 1h 35min - 23 - Super Spectacular Scientific Sessions Special Episode!! The co-hosts of Diabetes Care “On Air,” DiabetesBio, Diabetes Core Update, and Diabetes Day by Day get together to discuss highlights from the ADA’s 2024 Scientific Sessions.
Welcome to a very special, all-new episode (no. 23) of Diabetes Care “On Air.” While this podcast usually focuses exclusively on the research published in each month’s issue of Diabetes Care, this unique episode focuses on the incredible scholarly content of the 84th Scientific Sessions, which took place 21–24 June in Orlando, FL. Diabetes Care “On Air” co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, hosted a panel discussion with Kirk Habegger, PhD, Darleen Sandoval, PhD, and Kevin Williams, PhD, who co-host DiabetesBio, as well as Neil Skolnik, MD, co-host of Diabetes Core Update and Diabetes Day by Day. This episode is being released on three of our professional podcasts: Diabetes Care “On Air,” DiabetesBio, and Diabetes Core Update. This special episode is supported by an independent educational grant from Bayer.
This wide-ranging discussion begins with introductions and brief descriptions of the various podcasts, and then the panelists highlight their favorite sessions and events from the 84th Scientific Sessions---the new, high-impact research presented at the meeting, implications for future research, and clinical considerations and take-aways---across the “bench-to-bedside” spectrum of biomedical research, clinical research, and treatment advances. (Please note that anyone who registered for the event can still access the recorded content at ada2024.org until August 26.)
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Mon, 12 Aug 2024 - 54min - 22 - Dr. Albanese-O’Neill and Dr. DiMeglio on guidance for monitoring islet autoantibody–positive pre-stage 3 type 1 diabetes, Dr. Umpierrez on hyperglycemic crises in adults with diabetes, and more!!
Welcome to episode no. 22 (August 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the August 2024 issue of Diabetes Care.
0:42 Alice opens the show by reminding listeners that August 26 is the last day to access the online sessions from the 84th Scientific Sessions, which took place 21–24 June in Orlando, FL. Anyone who has registered can access the content at ada2024.org, so don’t forget to check it out!
1:26: Mike hosts the first interview of the episode, with Dr. Anastasia Albanese-O’Neill and Dr. Linda A. DiMeglio, corresponding author and last author, respectively, of “Consensus Guidance for Monitoring Individuals With Islet Autoantibody–Positive Pre-Stage 3 Type 1 Diabetes.” This consensus report is an editor-selected feature article appearing in the August 2024 issue and is openly accessible at https://doi.org/10.2337/dci24-0042.
28:37: Alice’s initial guest is Dr. Guillermo E. Umpierrez, first author of “Hyperglycemic Crises in Adults With Diabetes: A Consensus Report.” This consensus report is also an editor-selected feature article in the August 2024 issue and is openly accessible at https://doi.org/10.2337/dci24-0032.
52:19: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the August 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Daultrey et al. What Is the Influence of HIV Serostatus on HbA1c? A Prospective Analysis Using Continuous Glucose Monitoring. https://doi.org/10.2337/dc24-0225 Durnwald et al. Continuous Glucose Monitoring Profiles in Pregnancies With and Without Gestational Diabetes Mellitus. https://doi.org/10.2337/dc23-2149 Ghalwash et al. Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles. https://doi.org/10.2337/dc24-0198 Hessler et al. EMBARK: A Randomized, Controlled Trial Comparing Three Approaches to Reducing Diabetes Distress and Improving HbA1c in Adults With Type 1 Diabetes. https://doi.org/10.2337/dc23-2452 Kahn et al. Effect of Semaglutide on Regression and Progression of Glycemia in People With Overweight or Obesity but Without Diabetes in the SELECT Trial. https://doi.org/10.2337/dc24-0491 Lingvay et al. Semaglutide and Cardiovascular Outcomes by Baseline HbA1c and Change in HbA1c in People With Overweight or Obesity but Without Diabetes in SELECT. https://doi.org/10.2337/dc24-0764 Green et al. The Final Frontier in Diabetes Care: Implementing Research in Real-World Practice. https://doi.org/10.2337/dci24-0001To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Thu, 01 Aug 2024 - 1h 08min - 21 - Wrap-up of the 84th Scientific Sessions, David Sacks on optimal use of point-of-care HbA1c in clinical practice, Coco Fuhri Snethlage on residual β-cell function and time in range, and more!!
Welcome to episode no. 21 (July 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the July 2024 issue of Diabetes Care.
0:42 Mike and Alice open the show by talking about the spectacularly successful 84th Scientific Sessions, which took place 21–24 June in Orlando, FL. Mike shares his enjoyment of various symposia on clinical trial results, scientific award lectures, and even the basic science sessions. Alice, chair of the planning committee for the Scientific Sessions, thanks her fellow members on the planning committee and describes her number one problem with the event: deciding which session to attend!
3:56: Alice begins the interview portion of the show by hosting Dr. David Sacks, lead author on the review “Point-of-Care HbA1c in Clinical Practice: Caveats and Considerations for Optimal Use.” This review is an editor-selected feature article appearing in the July 2024 issue and is openly accessible at https://doi.org/10.2337/dci23-0040.
18:53: Mike talks to Dr. Coco M. Fuhri Snethlage, first author of “Residual β-Cell Function Is Associated With Longer Time in Range in Individuals With Type 1 Diabetes.” This study is also an editor-selected feature article in the July 2024 issue and is openly accessible at https://doi.org/10.2337/dc23-0776.
28:47: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the July 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Daniele et al. β-Cell Function, Incretin Effect, and Glucose Kinetics in Response to a Mixed Meal in Patients With Type 2 Diabetes Treated With Dapagliflozin Plus Saxagliptin. https://doi.org/10.2337/dc23-2051 Spaur et al. Association of Water Arsenic With Incident Diabetes in U.S. Adults: The Multi-Ethnic Study of Atherosclerosis and the Strong Heart Study. https://doi.org/10.2337/dc23-2231 Zhao et al. Hypoglycemic Response to Dorzagliatin in a Patient With GCK-MODY. https://doi.org/10.2337/dc23-2417 Fortmann et al. Medical Assistant Health Coaching for Type 2 Diabetes in Primary Care: Results From a Pragmatic Cluster Randomized Controlled Trial. https://doi.org/10.2337/dc23-2487 Bilal et al. Impaired Awareness of Hypoglycemia in Older Adults With Type 1 Diabetes: A Post Hoc Analysis of the WISDM Study. https://doi.org/10.2337/dc24-0201 Bratke et al. Ten Years of Improving Glycemic Control in Pediatric Diabetes Care: Data From the Norwegian Childhood Diabetes Registry. https://doi.org/10.2337/dc24-0086To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 05 Jul 2024 - 43min - 20 - Severe hypoglycemia among people with type 1 diabetes despite use of advanced technologies, the pros and cons of the glucose management indicator, excuses for not dancing like a chicken, and more!
Welcome to episode no. 20 (June 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the June 2024 issue of Diabetes Care.
1:20 Alice and Mike begin by talking about some of the many great things that will happen at the ADA’s 84th Scientific Sessions, which will take place 21–24 June in Orlando, FL.
4:11: Mike kicks off the interviews by bringing on Drs. Jennifer L. Sherr and Jeremy Pettus, first and last authors, respectively, of “Severe Hypoglycemia and Impaired Awareness of Hypoglycemia Persist in People With Type 1 Diabetes Despite Use of Diabetes Technology: Results From a Cross-sectional Survey.” This study is an editor-selected feature article appearing in the June 2024 issue and is openly accessible at https://doi.org/10.2337/dc23-1765.
17:32: Alice interviews Dr. Elizabeth Selvin, author of a Perspectives in Care called “The Glucose Management Indicator: Time to Change Course?” This study is also an editor-selected feature article in the June 2024 issue and is openly accessible at https://doi.org/10.2337/dci23-0086.
30:45: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the June 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Singh et al. Association of Continued Use of SGLT2 Inhibitors From the Ambulatory to Inpatient Setting With Hospital Outcomes in Patients With Diabetes: A Nationwide Cohort Study. https://doi.org/10.2337/dc23-1129 Voglová Hagerf et al. Accuracy and Feasibility of Real-time Continuous Glucose Monitoring in Critically Ill Patients After Abdominal Surgery and Solid Organ Transplantation. https://doi.org/10.2337/dc23-1663 Barmanray et al. The Specialist Treatment of Inpatients: Caring for Diabetes in Surgery (STOIC-D Surgery) Trial: A Randomized Controlled Trial of Early Intervention With an Electronic Specialist-Led Model of Diabetes Care. https://doi.org/10.2337/dc23-1905 Yang et al. Type 1 Diabetes Genetic Risk in 109,954 Veterans With Adult-Onset Diabetes: The Million Veteran Program (MVP). https://doi.org/10.2337/dc23-1927 Scheuer et al. Trends in Incidence of Hospitalization for Hypoglycemia and Diabetic Ketoacidosis in Individuals With Type 1 or Type 2 Diabetes With and Without Severe Mental Illness in Denmark From 1996 to 2020: A Nationwide Study. https://doi.org/10.2337/dc23-2394 Kwak et al. Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes. https://doi.org/10.2337/dc23-2274To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Wed, 05 Jun 2024 - 42min - 19 - Plant-based diets and diabetes, new details on the many forms of atypical diabetes, an invitation to dance like a chicken, and more!
Welcome to episode no. 19 (May 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the May 2024 issue of Diabetes Care.
2:00: Alice gets things going by bringing on Valerie K. Sullivan, first author of “Plant-Based Dietary Patterns and Incident Diabetes in the Atherosclerosis Risk in Communities (ARIC) Study.” Dr. Sullivan and her colleagues examined the association between plant-based dietary patterns and diabetes in a sample of Black and White adults. This study is an editor-selected feature article appearing in the May 2024 issue and is openly accessible at https://doi.org/10.2337/dc23-2013.
17:35: Mike interviews Stephen I. Stone, lead author of “Atypical Diabetes: What Have We Learned and What Does the Future Hold?” Dr. Stone’s group investigated several forms of atypical diabetes and outlined genetic and clinical resources for examining patients with atypical diabetes. This study is an editor-selected feature article appearing in the May 2024 issue and is openly accessible at https://doi.org/10.2337/dci23-0038.
35:55: Alice talks to the creator of the May issue cover art, Abby Gregg. A write-up of the artist by Benjamin Page is openly accessible at https://doi.org/10.2337/dci24-0027.
38:10: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the May 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Zhao et al. LHLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07). https://doi.org/10.2337/dc23-1947 Sugimoto et al. Impact of Type 2 Diabetes and Glycated Hemoglobin Levels Within the Recommended Target Range on Mortality in Older Adults With Cognitive Impairment Receiving Care at a Memory Clinic: NCGG-STORIES. https://doi.org/10.2337/dc23-2324 Cahill et al. Haptoglobin Phenotype and Intensive Glycemic Control for Coronary Artery Disease Risk Reduction in People With Type 2 Diabetes: The ADVANCE Study. https://doi.org/10.2337/dc23-2165 Tan et al. Socioeconomic Deprivation and the Risk of Sight-Threatening Diabetic Retinopathy: A Population-Based Cohort Study in the U.K. https://doi.org/10.2337/dc23-1626 Sherr et al. Exploring Factors That Influence Postexercise Glycemia in Youth With Type 1 Diabetes in the Real World: The Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) Study. https://doi.org/10.2337/dc23-2212 Sabag et al. Timing of Moderate to Vigorous Physical Activity, Mortality, Cardiovascular Disease, and Microvascular Disease in Adults With Obesity. https://doi.org/10.2337/dc23-2448To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Wed, 01 May 2024 - 49min - 18 - Special Collection of GRADE articles, feature on this month’s Profile in Progress, in-depth interview of Dr. David M. Nathan, and more!
Welcome to episode no. 18 (April 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the April 2024 issue of Diabetes Care.
Notably, this episode is a more expansive journey than usual. Dive in at your own pace—segment by segment— or all at once. You can find time stamps for each segment in the notes below.
Mike and Alice begin the show by announcing that the April episode will be unlike any episode of Diabetes Care “On Air” that they’ve done. This month, they focus on a Special Collection of articles in the April issue of Diabetes Care. This collection features 10 articles from the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) as well as a commentary on these articles. The full collection is openly accessible at https://diabetesjournals.org/collection/2066/Reports-from-the-GRADE-Study.
2:06: Mike and Alice begin the deep dive into the GRADE articles by bringing in David M. Nathan, chair of the steering committee for the GRADE study. They are then joined by Jennifer B. Green, a member of the GRADE Research Group and an associate editor of Diabetes Care.
9:56: After David M. Nathan and Jennifer B. Green give an overview and synopsis of the collection of GRADE articles, Alice brings in Matthew C. Riddle, former editor in chief of Diabetes Care and author of a commentary on the GRADE articles, to get his general impression of and insights into the GRADE collection. Dr. Riddle’s commentary on the GRADE collection is openly available at https://doi.org/10.2337/dci24-0008.
As the discussion continues, the speakers touch on each of the 10 articles of the Special Collection in the April issue of Diabetes Care. The following is a list of all the articles in the collection as well as the commentary, along with links to where these articles can be found (all are openly available).
Riddle. Individualizing treatment of type 2 diabetes after metformin: more insights from GRADE. https://doi.org/10.2337/dci24-0008 Gonzalez et al. Differential effects of type 2 diabetes treatment regimens on diabetes distress and depressive symptoms in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-2459 Garvey et al. Association of baseline factors with glycemic outcomes in GRADE: a comparative effectiveness randomized clinical trial. https://doi.org/10.2337/dc23-1782 Banerji et al. Mortality in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-1356 Cherrington et al. Does emotional distress predict worse glycemic control over time? Results from the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-0642 Hoogendoorn et al. Emotional distress predicts reduced type 2 diabetes treatment adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-1401 Rasouli et al. Longitudinal effects of glucose-lowering medications on β-cell responses and insulin sensitivity in type 2 diabetes: the GRADE randomized clinical trial. https://doi.org/10.2337/dc23-1070 Kirkman et al. Comparative effects of randomized second-line therapy for type 2 diabetes on a composite outcome incorporating glycemic control, body weight, and hypoglycemia: an analysis of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-1332 Utzschneider et al. Impact of insulin sensitivity and β-cell function over time on glycemic outcomes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE): differential treatment effects of dual therapy. https://doi.org/10.2337/dc23-1059 Cherrington et al. Impact of glucose-lowering medications on health-related quality of life in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-1648 Hollander et al. The use of rescue insulin in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). https://doi.org/10.2337/dc23-051642:50: Alice directs our attention to another kind of special article available in Diabetes Care, a Profile in Progress on none other than Dr. David M. Nathan. Alice chats with the author of the Profile, Deborah Wexler. Her piece, which Alice notes is “beautifully written,” is openly available at https://doi.org/10.2337/dci23-0095.
48:14: Mike and Alice are once again joined by David M. Nathan, this time for a discussion of his remarkable and extensive career as well as his dedication to advancing the understanding and treatment of diabetes.
1:10:00: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the April 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Birukov et al. Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts. https://doi.org/10.2337/dc23-1494 Al Rifai et al. Epidemiology and Prognostic Implications of Coronary Artery Calcium in Asymptomatic Individuals With Prediabetes: A Multicohort Study. https://doi.org/10.2337/dc23-1864 Sattar et al. Cardiovascular and Kidney Risks in Individuals With Type 2 Diabetes: Contemporary Understanding With Greater Emphasis on Excess Adiposity. https://doi.org/10.2337/dci23-0041 Foss-Freitas et al. Efficacy and Safety of Glucagon-Like Peptide 1 Agonists in a Retrospective Study of Patients With Familial Partial Lipodystrophy. https://doi.org/10.2337/dc23-1614 Al-Sofiani et al. A Real-World Prospective Study of the Effectiveness and Safety of Automated Insulin Delivery Compared With Other Modalities of Type 1 Diabetes Treatment During Ramadan Intermittent Fasting. https://doi.org/10.2337/dc23-1968 Abdelgani et al. Empagliflozin Reduces Liver Fat in Individuals With and Without Diabetes. https://doi.org/10.2337/dc23-1646To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Mon, 08 Apr 2024 - 1h 23min - 17 - Disparities in CGM use among children in urban and rural settings, the surprising role of sleep in the management of type 2 diabetes, a special offer for new ADA members, and more!
Welcome to episode no. 17 (March 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the March 2024 issue of Diabetes Care.
Mike and Alice begin the show by reminding listeners of ADA’s special offer to new members. Individuals who would like to take advantage of this time-limited discount can sign up for an ADA professional membership at professional.diabetes.org/membership. Use discount code “NEW24” for 25% off ADA membership. This offer will expire 31 March 2024.
1:28: Mike interviews Daniel R. Tilden, first author of “Disparities in Continuous Glucose Monitor Use Between Children With Type 1 Diabetes Living in Urban and Rural Areas.” This study is an editor-selected feature article appearing in the March 2024 issue and is openly accessible at https://doi.org/10.2337/dc23-1564.
16:55: Alice interviews Joseph Henson, Andrew P. Hall, and Melanie J. Davies, authors of “Waking Up to the Importance of Sleep in Type 2 Diabetes Management: A Narrative Review.” This study is an editor-selected feature article appearing in the March 2024 issue and is openly accessible at https://doi.org/10.2337/dci23-0037.
31:05: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the March 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Cheng et al. Managing Impending Nonsevere Hypoglycemia With Oral Carbohydrates in Type 1 Diabetes: The REVERSIBLE Trial. https://doi.org/10.2337/dc23-1328 Christensen et al. Kidney Disease in Women With Previous Gestational Diabetes Mellitus: A Nationwide Register-Based Cohort Study. https://doi.org/10.2337/dc23-1092 Virostko et al. Longitudinal Assessment of Pancreas Volume by MRI Predicts Progression to Stage 3 Type 1 Diabetes. https://doi.org/10.2337/dc23-1681 Fu et al. Risk Assessment for Gastrointestinal Diseases via Clinical Dimension and Genome-Wide Polygenic Risk Scores of Type 2 Diabetes: A Population-Based Cohort Study. https://doi.org/10.2337/dc23-0978 Roubille et al. Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT). https://doi.org/10.2337/dc23-1825 Chaudhary et al. Low Awareness of Diabetes as a Major Risk Factor for Cardiovascular Disease in Middle- and High-Income Countries. https://doi.org/10.2337/dc23-1731Don’t forget our special offer for new ADA members! Go to professional.diabetes.org/membership and use discount code “NEW24” for 25% off ADA membership. Offer expires 31 March 2024.
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Thu, 29 Feb 2024 - 44min - 16 - A talk with the February Diabetes Care cover artist, best types of physical activity to improve glycemic control, pharmacogenomic variants associated with metformin glycemic response, special offer for new ADA members, and more!
Welcome to episode no. 16 (February 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the February 2024 issue of Diabetes Care.
Alice begins the show by reminding listeners of ADA’s special offer to new members. Individuals who would like to take advantage of this time-limited discount can sign up for an ADA professional membership at professional.diabetes.org/membership. Use discount code “NEW24” for 25% off ADA membership. This offer will expire 31 March 2024.
2:10: Alice interviews Laura Jacobsen, who took the photograph featured on the cover of the February issue of Diabetes Care. Each month, the editors of Diabetes Care select cover art from reader submissions. If you are interested in submitting cover art, please visit https://diabetesjournals.org/care/pages/submit_a_cover_image. Read more about Dr. Jacobsen and her photo in “About the Artist: Laura Jacobsen, MD” (https://diabetesjournals.org/care/article/47/2/181/154139/About-the-Artist-Laura-Jacobsen-MD).
8:50: Mike interviews Borja del Pozo Cruz, one of the senior authors of “Optimal Dose and Type of Physical Activity to Improve Glycemic Control in People Diagnosed With Type 2 Diabetes: A Systematic Review and Meta-analysis.” https://doi.org/10.2337/dc23-0800
25:30: Alice interviews Baojun Wu and L. Keoki Williams, first author and senior author, respectively, of “Genome-Wide Association Study Identifies Pharmacogenomic Variants Associated With Metformin Glycemic Response in African American Patients With Type 2 Diabetes.” https://doi.org/10.2337/dc22-2494
In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the February 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Karagiannis et al. A Methodological Framework for Meta-analysis and Clinical Interpretation of Subgroup Data: The Case of Major Adverse Cardiovascular Events With GLP-1 Receptor Agonists and SGLT2 Inhibitors in Type 2 Diabetes. https://doi.org/10.2337/dc23-0925 Wang et al. Vaspin: A Novel Biomarker Linking Gluteofemoral Body Fat and Type 2 Diabetes Risk. https://doi.org/10.2337/dc23-1488 Beato-Bibora et al. A Multicenter Prospective Evaluation of the Benefits of Two Advanced Hybrid Closed-Loop Systems in Glucose Control and Patient-Reported Outcomes in a Real-world Setting. https://doi.org/10.2337/dc23-1355 Visaria et al. Ambient Heat and Risk of Serious Hypoglycemia in Older Adults With Diabetes Using Insulin in the U.S. and Taiwan: A Cross-National Case-Crossover Study. https://doi.org/10.2337/dc23-1189 Foster et al. Low-Dose Antithymocyte Globulin: A Pragmatic Approach to Treating Stage 2 Type 1 Diabetes. https://doi.org/10.2337/dc23-1750 Kaminski et al. Assessment of Glycemic Control by Continuous Glucose Monitoring, Hemoglobin A1c, Fructosamine, and Glycated Albumin in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes. https://doi.org/10.2337/dc23-1276Don’t forget our special offer for new ADA members! Go to professional.diabetes.org/membership and use discount code “NEW24” for 25% off ADA membership. Offer expires 31 March 2024.
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 02 Feb 2024 - 57min - 15 - New Year greetings from Mike and Alice, psychosocial care for people with diabetic neuropathy, diabetes risk factors for South Asians, special offer for new ADA members, and more!
Welcome to episode no. 15 (January 2024) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the January 2024 issue of Diabetes Care.
After wishing all the listeners a happy and healthy New Year, Alice and Mike announce ADA’s special offer to new members. Individuals who would like to take advantage of this time-limited discount can sign up for an ADA professional membership at professional.diabetes.org/membership. Use discount code “NEW24” for 25% off ADA membership. This offer will expire 31 March 2024.
3:28: Mike interviews Frans Pouwer and Loretta Vileikyte, first and senior authors, respectively, of a Perspectives on Care titled “Psychosocial Care for People with Diabetic Neuropathy: Time for Action” (https://doi.org/10.2337/dci23-0033).
25:19: Alice interviews Alka Kanaya about her 2023 Kelly West Award lecture, “Diabetes in South Asians: Uncovering Novel Risk Factors With Longitudinal Epidemiologic Data: Kelly West Award Lecture 2023” https://doi.org/10.2337/dci23-0068.
44:15: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the January 2024 issue of Diabetes Care. Studies highlighted in this segment include:
Sanusi et al. Association of Continuous Glucose Monitoring Metrics With Pregnancy Outcomes in Patients With Preexisting Diabetes. https://doi.org/10.2337/dc23-0636 Sherwood et al. Randomized Trial of the Insulin-Only iLet Bionic Pancreas for the Treatment of Cystic Fibrosis– Related Diabetes. https://doi.org/10.2337/dc23-1411 Baekdal et al. Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study. https://doi.org/10.2337/dc23-0645 Parviainen et al. Incidence of Type 1 Diabetes in Relation to Exposure to Rotavirus Infections in Pre- and Postvaccine Birth Cohorts in Finland. https://doi.org/10.2337/dc23-1203 Umapathysivam et al. Euglycemic Ketoacidosis in Two Patients Without Diabetes After Introduction of Sodium–Glucose Cotransporter 2 Inhibitor for Heart Failure With Reduced Ejection Fraction. https://doi.org/10.2337/dc23-1163 Narcisse et al. Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease and Diabetes Mellitus: A Subgroup Analysis of the ADAPTABLE Trial. https://doi.org/10.2337/dc23-0749Don’t forget our special offer for new ADA members! Go to professional.diabetes.org/membership and use discount code “NEW24” for 25% off ADA membership. Offer expires 31 March 2024.
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Tue, 02 Jan 2024 - 59min - 14 - Special Episode: Social Determinants of Health Symposium and Clinical Care Commission Report to Congress
Welcome to episode no. 14, a very special episode of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, along with special guests Dr. Stephanie Fitzpatrick and Dr. Seth Berkowitz, for an examination of the 2023 Diabetes Care Symposium, the 2023 Clinical Care Commission Report to Congress, and the life and achievements of Dr. Felicia Hill-Briggs.
0:38: Mike introduces the guests for this special episode, Drs. Stephanie Fitzpatrick and Dr. Seth Berkowitz. Alice announces that she and Mike are dedicating this special episode to the memory of Dr. Felicia Hill-Briggs, who passed away on 23 June 2023. Dr. Fitzpatrick, who did her postdoctoral fellowship with Dr. Hill-Briggs, remembers Dr. Hill-Briggs for her professional achievements and her collaborative and thoughtful approach to research.
3:00: Mike talks with Dr. Fitzpatrick about the symposium article that she coauthored with Dr. Hill-Briggs, “Overview of Social Determinants of Health in the Development of Diabetes.” This study is from the Diabetes Care Symposium that appears in the September 2023 issue, and it is openly accessible at https://doi.org/10.2337/dci23-0001. The entire collection of Diabetes Care Symposium articles is openly accessible at https://diabetesjournals.org/collection/1803/Diabetes-Care-Symposium-2023.
6:00: Alice interviews Dr. Berkowitz, lead author of the Diabetes Care Symposium article “Three Lessons About Diabetes and the Social Determinants of Health,” which was also presented at the Diabetes Care Symposium and appeared in the September 2023 issue of Diabetes Care. It is openly accessible at https://doi.org/10.2337/dci23-0045. Alice and Dr. Berkowitz also discuss the article by Levi et al. that was presented at the symposium, “Food Insecurity and Diabetes: Overview of Intersections and Potential Dual Solutions.” This article is also openly accessible at https://doi.org/10.2337/dci23-0002.
13:20: Mike and Dr. Fitzpatrick discuss the final article in the Diabetes Care Symposium on SDOH, “The Impact of Neighborhoods on Diabetes Risk and Outcomes: Centering Health Equity,” by Mujahid et al. This article is openly accessible at https://doi.org/10.2337/dci23-0003.
18:20: Alice brings up the Clinical Care Commission Report to Congress, which appeared as a special article collection in the February 2023 issue of Diabetes Care. She and Dr. Berkowitz discuss the importance of this collection, which focused in part on SDOH and the development of diabetes. The collection of articles from the Clinical Care Commission Report to Congress is available at https://diabetesjournals.org/collection/1586/The-Clinical-Care-Commission-Report-to-Congress.
To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Mon, 11 Dec 2023 - 29min - 13 - Holiday greetings, multiple long-term conditions for people with diabetes, dasiglucagon therapy for postprandial hypoglycemia after gastric bypass, light-dark and activity-rest rhythms and glucose metabolism, and more!
Welcome to episode no. 13 (December 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the December 2023 issue of Diabetes Care.
1:45: Alice interviews Kamlesh Khunti, lead author of “Diabetes and Multiple Long-term Conditions: A Review of Our Current Global Health Challenge.” This study is an editor-selected feature article appearing in the December 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0035.
18:10: Mike interviews Casper K. Nielsen, lead author of “Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial.” This study is also an editor-selected feature article appearing in the December 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-1193.
34:00: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the December 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Xiao et al. Alignment Between 24-h Light-Dark and Activity-Rest Rhythms Is Associated With Diabetes and Glucose Metabolism in a Nationally Representative Sample of American Adults. https://doi.org/10.2337/dc23-1034 Zou et al. Rare Variant in Metallothionein 1E Increases the Risk of Type 2 Diabetes in a Chinese Population. https://doi.org/10.2337/dc22-2031 Zaharia et al. Reduced Insulin Clearance Differently Relates to Increased Liver Lipid Content and Worse Glycemic Control in Recent-Onset Type 2 and Type 1 Diabetes. https://doi.org/10.2337/dc23-1267 Hsieh et al. COVID-19 Vaccination Prior to SARS-CoV-2 Infection Reduced Risk of Subsequent Diabetes Mellitus: A Real-World Investigation Using U.S. Electronic Health Records. https://doi.org/10.2337/dc23-0936 Renard et al. Safety and Efficacy of Sustained Automated Insulin Delivery Compared With Sensor and Pump Therapy in Adults With Type 1 Diabetes at High Risk for Hypoglycemia: A Randomized Controlled Trial. https://doi.org/10.2337/dc23-0685 Donovan et al. A Randomized Trial of Closed-Loop Insulin Delivery Postpartum in Type 1 Diabetes. https://doi.org/10.2337/dc23-0882To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 01 Dec 2023 - 47min - 12 - Happy World Diabetes Day to all, predicting cardiometabolic health in type 2 diabetes, drug effectiveness for individuals with diabetes and frailty, and more!
Welcome to episode no. 12 (November 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the November 2023 issue of Diabetes Care.
1:43: Mike gets things started with a November fun fact about diabetes: World Diabetes Day is November 14th! The 14th of November was chosen because it is Sir Fredrick Banting’s birthday. More information on World Diabetes Day can be found at worlddiabetesday.org.
2:20: Mike interviews Naveed Sattar, lead author of “Prediction of Cardiometabolic Health Through Changes in Plasma Proteins With Intentional Weight Loss in the DiRECT and DIADEM-I Randomized Clinical Trials of Type 2 Diabetes Remission.” This study is an editor-selected feature article appearing in the November 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0602.
18:37: Alice interviews Alexander Kutz, lead author of “Comparative Cardiovascular Effectiveness and Safety of SGLT-2 Inhibitors, GLP-1 Receptor Agonists, and DPP-4 Inhibitors According to Frailty in Type 2 Diabetes.” This study is also an editor-selected feature article appearing in the November 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0671.
30:15: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the November 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Mizrak et al. Declining Incidence Rates of Distal Symmetric Polyneuropathy in People With Type 1 and Type 2 Diabetes in Denmark, With Indications of Distinct Patterns in Type 1 Diabetes. https://doi.org/10.2337/dc23-0312 Sathish et al. Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual-Participant Data Meta-analysis of Randomized Controlled Trials. https://doi.org/10.2337/dc23-0696 Stougaard et al. Time Trends in the Incidence of Diabetic Ketoacidosis Leading to Hospital Admission Among Adults With Type 1 Diabetes—A Nationwide Danish Register Study. https://doi.org/10.2337/dc23-0475 Song et al. Point-of-Care Capillary Blood Ketone Measurements and the Prediction of Future Ketoacidosis Risk in Type 1 Diabetes. https://doi.org/10.2337/dc23-0840 Hernandez et al. Randomization to a Provided Higher-Complex-Carbohydrate Versus Conventional Diet in Gestational Diabetes Results in Similar Maternal 24-Hour Glycemia and Newborn Adiposity. https://doi.org/10.2337/dc23-0617 Boughton et al. Fully Closed-Loop Glucose Control Compared With Insulin Pump Therapy With Continuous Glucose Monitoring in Adults With Type 1 Diabetes and Suboptimal Glycemic Control: A Single-Center, Randomized, Crossover Study. https://doi.org/10.2337/dc23-0728 Llamosas-Falcón et al. The Relationship Between Alcohol Consumption, Body Mass Index and Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis. https://doi.org/10.2337/dc23-1015To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Thu, 26 Oct 2023 - 44min - 11 - Banting 100 years later, AI and retinopathy screening and diagnosis, stage 1 type 1 diabetes and islet autoimmunity, and more!
Remembering a critical breakthrough in diabetes research on a fateful night over 100 years ago, Anand E. Rajesh and Aaron Y. Lee on the incredible potential of artificial intelligence in screening for and diagnosing diabetic retinopathy, Brigitte I. Frohnert on stage 1 type 1 diabetes and multiple islet autoimmunity, and more!
Welcome to episode no. 11 (October 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the October 2023 issue of Diabetes Care.
0:45: Alice kicks off the episode with a fun October fact about a critical breakthrough in diabetes research that occurred in 1920. This breakthrough came in the form of an idea in a dream of Sir Fredrick Banting in the early morning hours of Halloween that year, and this idea contributed greatly to the discovery and successful purification of insulin.
2:20: Alice interviews Anand E. Rajesh and Aaron Y. Lee, authors of “Artificial Intelligence and Diabetic Retinopathy: AI Framework, Prospective Studies, Head-to-head Validation, and Cost-effectiveness” This study is an editor-selected feature article appearing in the October 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0032.
22:54: Mike interviews Brigitte I. Frohnert, lead author of “Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity.” This study is also an editor-selected feature article appearing in the October 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-1960.
43:36: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the October 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Sacks et al. Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. https://doi.org/10.2337/dci23-0036 Speksnijder et al. Effect of Postmenopausal Hormone Therapy on Glucose Regulation in Women With Type 1 or Type 2 Diabetes: A Systematic Review and Meta-analysis. https://doi.org/10.2337/dc23-0451 Ahmed et al. Genetic Evidence Strongly Supports Managing Weight and Blood Pressure in Addition to Glycemic Control in Preventing Vascular Complications in People With Type 2 Diabetes. https://doi.org/10.2337/dc23-0855 Wei et al. All-Cause Mortality and Cardiovascular and Microvascular Diseases in Latent Autoimmune Diabetes in Adults. https://doi.org/10.2337/dc23-0739 Osafehinti et al. Type 1 Diabetes Genetic Risk Score Differentiates Subgroups of Ketosis-Prone Diabetes. https://doi.org/10.2337/dc23-0622 Berg et al. A Skin Care Program to Prevent Skin Problems due to Diabetes Devices in Children and Adolescents: A Cluster-Controlled Intervention Study. https://doi.org/10.2337/dc23-0462To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 29 Sep 2023 - 53min - 10 - Slowing diabetes progression, artificial sweeteners and type 2 diabetes risk, and more!
Announcement of an upcoming special episode of Diabetes Care “On Air” on diabetes and social determinants of health, Sandra C. Naamann and George L. Bakris on the pillars of therapy for slowing diabetes progression, Mathilde Touvier on artificial sweeteners and type 2 diabetes risk, and more!
Welcome to episode no. 10 (September 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the September 2023 issue of Diabetes Care.
0:43: Alice announces a special episode of Diabetes Care “On Air,” to be released later in the month. This special episode will focus on this year’s Diabetes Care Symposium on the impact of social determinants of health for diabetes development and care. The episode will feature a panel discussion with the authors of the articles presented at the symposium.
1:15: Mike interviews Sandra C. Naaman and George L. Bakris, authors of “Diabetic Nephropathy: Update on Pillars of Therapy Slowing Progression.” This study is an editor-selected feature article appearing in the September 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0030.
30:30: Alice interviews Mathilde Touvier, senior author of “Artificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Santé Cohort.” This study is also an editor-selected feature article appearing in the September 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0206.
41:30: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the September 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Rafael Simó et al. Rapid Reduction of HbA1c and Early Worsening of Diabetic Retinopathy: A Real-World Population-Based Study in Subjects With Type 2 Diabetes. https://doi.org/10.2337/dc22-2521 Jose Garcia-Tirado et al. Assessment of Meal Anticipation for Improving Fully Automated Insulin Delivery in Adults With Type 1 Diabetes. https://doi.org/10.2337/dc23-0119 Oliver Artz et al. Grading Fractures on Foot and Ankle X-rays and MRI Scans in the Active Charcot Foot in Diabetes: How Strong Is the Agreement Between Modalities? https://doi.org/10.2337/dc23-0220 Yaogan Luo et al. Diet-Related Lipidomic Signatures and Changed Type 2 Diabetes Risk in a Randomized Controlled Feeding Study With Mediterranean Diet and Traditional Chinese or Transitional Diets. https://doi.org/10.2337/dc23-0314 Rodolfo J. Galindo et al. A Randomized Controlled Trial Comparing the Efficacy and Safety of IDegLira Versus Basal-Bolus in Patients With Poorly Controlled Type 2 Diabetes and Very High HbA1c ³9–15%: DUAL HIGH Trial. https://doi.org/10.2337/dc22-2426 Andrea Kalus et al. Evaluation of Insulin Pump Infusion Sites in Type 1 Diabetes: The DERMIS Study. https://doi.org/10.2337/dc23-0426To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Tue, 05 Sep 2023 - 53min - 9 - Taking stock of Diabetes Care “On Air” so far, technology in the care of older adults with diabetes, metformin and the risk of congenital malformations in pregnant individuals with type 2 diabetes, and more
Welcome to episode no. 9 (August 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the August 2023 issue of Diabetes Care.
0:52: Before launching into this month’s feature interviews, Alice and Mike recap their first few months of working together on Diabetes Care “On Air.” Mike emphasizes how much he’s learned from the interviewees and from Alice, and he shares his hope that listeners also find the podcast enlightening. Alice has been impressed with how passionate the interviewers are about the diabetes research they are conducting. She also takes us behind the scenes to reveal that she performs her podcasting from her closet!
2:11: Mike interviews Elbert S. Huang, first author of “The Growing Role of Technology in the Care of Older Adults with Diabetes.” This study is an editor-selected feature article appearing in the August 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0021.
19:08: Alice interviews Lars J. Kjerpeseth, first author of “Metformin Versus Insulin and Risk of Major Congenital Malformations in Pregnancies With Type 2 Diabetes: A Nordic Register-Based Cohort Study.” This study is also an editor-selected feature article appearing in the August 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0256.
28:05: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the August 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Katharine J. McCarthy et al. Influence of Gestational Diabetes on Diabetes Risk and Glycemic Control in a Retrospective Population-Based Cohort. https://doi.org/10.2337/dc22-1676 Ruchi Sharan et al. The Association of Homelessness With Rates of Diabetes Complications: A Population-Based Cohort Study. https://doi.org/10.2337/dc23-0211 Fady T. Botros et al. Dulaglutide and Kidney Function-Related Outcomes in Type 2 Diabetes: A REWIND Post Hoc Analysis. https://doi.org/10.2337/dc23-0231 Hiddo J.L. Heerspink et al. Effects of Tirzepatide Versus Insulin Glargine on Cystatin C-Based Kidney Function: A SURPASS-4 Post Hoc Analysis. https://doi.org/10.2337/dc23-0261 Aaron J. Deutsch et al. Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes. https://doi.org/10.2337/dc23-0353 Kristen J. Nadeau et al. Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results From the TODAY Study. https://doi.org/10.2337/dc23-0560 Frederik Pagh Bredahl Kristensen et al. The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity. https://doi.org/10.2337/dc23-0079To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Wed, 02 Aug 2023 - 38min - 8 - Episode 8, July 2023 Diabetes Care "On Air"
Welcome to episode no. 8 (July 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the July 2023 issue of Diabetes Care.
0:42: Mike and Alice discuss the spectacularly successful 83rd Scientific Sessions of the ADA, which occurred June 23 to 26 in San Diego, CA. The co-hosts discuss the “incredible,” “exciting,” and “terrific” sessions, lectures, and study results presentations. Alice relates her joy in making new connections and renewing old ones, and Mike notes that the high in-person attendance infused the whole event with a dynamic, collaborative energy. He also highlights the timeliness and importance of the symposium on diabetes and social determinants of health (SDOH) that was featured at the Scientific Sessions. Alice and Mike plan to do a special podcast on the SDOH symposium in the near future.
4:02: Alice interviews Jean-Philippe Drouin-Chartier, senior author of the article “Ultra-Processed Food Consumption and Risk of Type 2 Diabetes: Three Large Prospective U.S. Cohort Studies.” This study is an editor-selected feature article appearing in the July 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-1993.
15:20: Mike interviews Edward W. Gregg, lead author of “Use of Real-World Data in Population Science to Improve the Prevention and Care of Diabetes-Related Outcomes.” This study is also an editor-selected feature article appearing in the July 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-1438.
27:50: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the July 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Xinyu Li et al. Potential Value of Identifying Type 2 Diabetes Subgroups for Guiding Intensive Treatment: A Comparison of Novel Data-Driven Clustering With Risk-Driven Subgroups. https://doi.org/10.2337/dc22-2170 Laurent Castera et al. High Prevalence of NASH and Advanced Fibrosis in Type 2 Diabetes: A Prospective Study of 330 Outpatients Undergoing Liver Biopsies for Elevated ALT, Using a Low Threshold. https://doi.org/10.2337/dc22-2048 Jingyi Qian et al. Association of Timing of Moderate-to-Vigorous Physical Activity With Changes in Glycemic Control Over 4 Years in Adults With Type 2 Diabetes From the Look AHEAD Trial. https://doi.org/10.2337/dc22-2413 Mary R. Rooney et al. Global Prevalence of Prediabetes. https://doi.org/10.2337/dc22-2376 Spencer M. Erickson et al. Metformin for Treatment of Acute COVID-19: Systematic Review of Clinical Trial Data Against SARS-CoV-2. https://doi.org/10.2337/dc22-2539 Carol J. Levy et al. At-Home Use of a Pregnancy-Specific Zone-MPC Closed-Loop System for Pregnancies Complicated by Type 1 Diabetes: A Single-Arm, Observational Multicenter Study. https://doi.org/10.2337/dc23-0173To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 30 Jun 2023 - 40min - 7 - Episode 7, June 2023 Diabetes Care "On Air"
Welcome to episode no. 7 (June 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the June 2023 issue of Diabetes Care.
0:41: Mike and Alice discuss the 83rd Scientific Sessions of the ADA, which will occur June 23 to 26 in San Diego, CA. Alice, who happens to be the Chair of the Scientific Sessions Planning Committee, describes some of the exciting changes attendees can expect this year, and both co-hosts share which of the many lectures, debates, and sessions they are looking forward to the most, including a new event called The Innovation Challenge and the Keynote address by former director of the National Institutes of Health Dr. Francis Collins. Alice notes a debate in which our esteemed host Mike Rickels will be participating on b-cell replacement therapies vs. artificial pancreas technologies, and the results of several major clinical trials that will be presented, including SURMOUNT-2, OASIS 1, PIONEER PLUS, COORDINATE-Diabetes, and CLEAR Outcomes.
6:58: Mike interviews Angus G. Jones, senior author of the article “Age of Diagnosis Does Not Alter the Presentation or Progression of Robustly Defined Adult-Onset Type 1 Diabetes.” This study is an editor-selected feature article appearing in the June 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-2159.
22:05: Alice has an enlightening chat with Andrea Kelly, one of the authors of the article “Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes.” This study is also an editor-selected feature article in the June 2023 issue and can be freely accessed at https://doi.org/10.2337/dc23-0380.
42:47: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the June 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Tessa Strain et al. Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults. https://doi.org/10.2337/dc22-1467 Nicolette R. den Braver et al. Higher Neighborhood Drivability Is Associated With a Higher Diabetes Risk in Younger Adults: A Population-Based Cohort Study in Toronto, Canada. https://doi.org/10.2337/dc22-1549 Guoying Wang. Plasma Insulin Concentration in Newborns and Children and Age at Menarche. https://doi.org/10.2337/dc22-2017 Mireille N.M. van Poppel et al. Is the Biphasic Effect of Diabetes and Obesity on Fetal Growth a Risk Factor for Childhood Obesity? https://doi.org/10.2337/dc22-2409 Sabina Wagner et al. Upper-Extremity Impairments in Type 1 Diabetes: Results From a Controlled Nationwide Study. https://doi.org/10.2337/dc23-0063 Luz E. Castellanos et al. The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes. https://doi.org/10.2337/dc22-1478 Scott J. Pilla et al. A National Physician Survey of Deintensifying Diabetes Medications for Older Adults With Type 2 Diabetes. https://doi.org/10.2337/dc22-2146To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Fri, 02 Jun 2023 - 57min - 6 - Episode 6, May 2023 Diabetes Care "On Air"
Welcome to episode no. 6 (May 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the May 2023 issue of Diabetes Care.
1:45: Alice interviews Rohan Arora, contributor of the cover art on the May 2023 issue of Diabetes Care. Rohan was born in India and was diagnosed with diabetes 14 years ago. Today he is a designer, a researcher, and a certified diabetes educator. He is also the head of the Delhi Chapter of the Blue Circle Diabetes Foundation (bluecircle.foundation), a nongovernmental organization in India committed to diabetes education and advocacy. Rohan’s artwork, “Sugar Moon,” is inspired by “a mother’s empathy and how with love and joy in small things we can overcome all odds.” Please check out the cover and a brief profile of Rohan and his artwork in the May 2023 issue of Diabetes Care: https://diabetesjournals.org/care/issue/46/5.
7:42: Mike chats with William Russell of Vanderbilt University Medical Center. Dr. Russell is the lead author of “Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial,” which was coordinated by the Type 1 Diabetes TrialNet Study Group. This study is an editor-selected feature article appearing in the May 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-2200.
24:29: Alice discusses “Metformin and Cancer: Solutions to a Real-World Evidence Failure” with senior author Sammy Suissa of McGill University. As Alice describes, Dr. Suissa’s review article, which is coauthored by Oriana Hoi Yun Yu, is “a cautionary tale of the potential pitfalls of observational study design and the steps we can take to right the wrongs of the past.” This fascinating article can be freely accessed at https://doi.org/10.2337/dci22-0047.
41:31 In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the May 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Siham Abdelgani et al. Distinct Mechanisms Responsible for the Increase in Glucose Production and Ketone Formation Caused by Empagliflozin in T2DM Patients. https://doi.org/10.2337/dc22-0885 Paul M. McKeigue et al. Relation of Incident Type 1 Diabetes to Recent COVID-19 Infection: Cohort Study Using e-Health Record Linkage in Scotland. https://doi.org/10.2337/dc22-0385 Naomi Holman et al. Comparative Incidence of Diabetes Following Hospital Admission for COVID-19 and Pneumonia: A Cohort Study. https://doi.org/10.2337/dc22-0670 Christof M. Kazda et al. Novel Once-Weekly Basal Insulin Fc Achieved Similar Glycemic Control With a Safety Profile Comparable to Insulin Degludec in Patients With Type 1 Diabetes. https://doi.org/10.2337/dc22-2395 Juliana M. Bue-Valleskey et al. Once-Weekly Basal Insulin Fc Demonstrated Similar Glycemic Control to Once-Daily Insulin Degludec in Insulin-Naive Patients With Type 2 Diabetes: A Phase 2 Randomized Control Trial. https://doi.org/10.2337/dc22-2396 Anastasios Mangelis et al. People With Type 1 Diabetes of African Caribbean Ethnicity Are at Increased Risk of Developing Sight-Threatening Diabetic Retinopathy. https://doi.org/10.2337/dc22-2118 Tim Heise et al. Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes. https://doi.org/10.2337/dc22-1710 Vera Lehmann et al. Noninvasive Hypoglycemia Detection in People With Diabetes Using Smartwatch Data. https://doi.org/10.2337/dc22-2290To learn more about Diabetes Care, please visit diabetesjournals.org/care. Interested in submitting cover art to the journal? Please visit https://diabetesjournals.org/care/pages/submit_a_cover_image.
Tue, 02 May 2023 - 53min - 5 - Episode 5, April 2023 Diabetes Care "On Air"
Welcome to episode no. 5 (April 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the April 2023 issue of Diabetes Care.
0:52: Mike interviews Aaron J. Deutsch and Miriam S. Udler of the Harvard Medical School and Massachusetts General Hospital. Aaron and Miriam are the lead and senior authors, respectively, of “Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms.” This article, which can be freely accessed at https://doi.org/10.2337/dc22-1833, is one of the editor-selected feature articles in the April 2023 issue of Diabetes Care.
12:23: Alice is joined by Leonard E. Egede of the Medical College of Wisconsin. Dr. Egede is the lead author of “Structural Racism as an Upstream Social Determinant of Diabetes Outcomes: A Scoping Review,” another editor-selected article appearing in the April 2023 issue and openly accessible at https://doi.org/10.2337/dci22-0044.
21:05: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the April 2023 issue of Diabetes Care. Studies highlighted in this segment include:
M.C. Riddell et al. Examining the Acute Glycemic Effects of Different Types of Structured Exercise Sessions in Type 1 Diabetes in a Real-World Setting: The Type 1 Diabetes and Exercise Initiative (T1DEXI). https://doi.org/10.2337/dc22-1721 R. Aronson et al. Effect of Mini-Dose Ready-to-Use Liquid Glucagon on Preventing Exercise-Associated Hypoglycemia in Adults With Type 1 Diabetes. https://doi.org/10.2337/dc22-1145 M.R. Rooney et al. Proteomic Predictors of Incident Diabetes: Results From the Atherosclerosis Risk in Communities (ARIC) Study. https://doi.org/10.2337/dc22-1830 G.M. Davis et al. Safety and Efficacy of the Omnipod 5 Automated Insulin Delivery System in Adults With Type 2 Diabetes: From Injections to Hybrid Closed-Loop Therapy. https://doi.org/10.2337/dc22-1915 T.P. Adesoba and C.C. Brown. Trends in the Prevalence of Lean Diabetes Among U.S. Adults, 2015–2020. https://doi.org/10.2337/dc22-1847 J.I. Malone et al. on behalf of the Diabetes Control and Complications Trial (DCCT)-Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group Retinopathy During the First 5 Years of Type 1 Diabetes and Subsequent Risk of Advanced Retinopathy. https://doi.org/10.2337/dc22-1711 L. Bakinowska et al. Exocrine Proteins Including Trypsin(ogen) as a Key Biomarker in Type 1 Diabetes. https://doi.org/10.2337/dc22-1317 B.R. Shah et al. Growing Income-Related Disparities in Cardiovascular Hospitalizations Among People With Diabetes, 1995–2019: A Population-Based Study. https://doi.org/10.2337/dc22-1936To learn more about Diabetes Care, please visit diabetesjournals.org/care.
Mon, 27 Mar 2023 - 35min - 4 - Episode 4, March 2023 Diabetes Care "On Air"
Welcome to episode no. 4 (March 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the March 2023 issue of Diabetes Care.
1:11: The March 2023 cover of Diabetes Care features a stunning self-portrait by Michael Natter, MD. Dr. Natter, who was diagnosed with type 1 diabetes at the age of 9, is an endocrinologist at NYU Langone Health. Before pursuing his medical degree, he studied visual art at Skidmore College. Dr. Natter shares with Alice how his background in studio art has allowed him to approach medicine through a nontraditional lens. Dr. Natter’s piece on the March 2023 cover is titled “Calloused Fingertips,” and as he explains, it is a self-portrait created through a mosaic of used diabetes test strips. Follow Dr. Natter on Instagram (@mike.natter), Twitter (@mike_natter), and TikTok (@mikenatter).
7:05: Mike interviews Wei Perng, PhD, MPH, of the University of Colorado School of Public Health and lead author of “Youth-Onset Type 2 Diabetes: The Epidemiology of an Awakening.” This Review Article, which can be freely accessed at https://doi.org/10.2337/dci22-0046, is one of the editor-selected feature articles in the March 2023 issue of Diabetes Care.
26:40: Alice is joined by Louise L. Stentebjerg, MD, PhD-candidate, of Steno Diabetes Center Odense. Dr. Stentebjerg is the lead author of “Roux-en-Y Gastric Bypass Increases Glycemic Excursions During Pregnancy and Postpartum: A Prospective Cohort Study,” another editor-selected article appearing in the March 2023 issue and openly accessible at https://doi.org/10.2337/dc22-1357.
34:25: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing other interesting articles in the March 2023 issue of Diabetes Care. Studies highlighted in this segment include:
M.R. Rigby et al. Two-Year Follow-up From the T1GER Study: Continued Off-Therapy Metabolic Improvements in Children and Young Adults With New-Onset T1D Treated With Golimumab and Characterization of Responders. https://doi.org/10.2337/dc22-0908 T.A. Khan et al. Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies. https://doi.org/10.2337/dc22-1024 D.M. Wilson et al., and the Type 1 Diabetes TrialNet Study Group. CGM Metrics Identify Dysglycemic States in Participants From the TrialNet Pathway to Prevention Study. https://doi.org/10.2337/dc22-1297 R. Retnakaran et al. Treatment of Gestational Diabetes Mellitus and Maternal Risk of Diabetes After Pregnancy. https://doi.org/10.2337/dc22-1786 V. Rotbain Curovic et al. Optimization of Albuminuria-Lowering Treatment in Diabetes by Crossover Rotation to Four Different Drug Classes: A Randomized Crossover Trial. https://doi.org/10.2337/dc22-1699 J.R. Herges et al. Glucagon Prescribing and Costs Among U.S. Adults With Diabetes, 2011–2021. https://doi.org/10.2337/dc22-1564.To learn more about Diabetes Care, please visit diabetesjournals.org/care.
Fri, 03 Mar 2023 - 44min - 3 - Special Episode: National Clinical Care Commission Report to Congress on Diabetes Treatment and Prevention
Welcome to episode no. 3 (February 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life.
This special episode of Diabetes Care “On Air” is devoted to the National Clinical Care Commission (NCCC) Report to Congress.
The NCCC was a federal advisory committee charged with leveraging federal policies and programs to more effectively prevent and control diabetes. In January 2022, the NCCC issued its final report to Congress. That transformational report contained 39 specific recommendations, including 3 foundational recommendations, that addressed the necessity of an all-of-government approach to diabetes, health equity, and access to health care.
Diabetes Care is excited to announce that the February 2023 issue features an openly accessible seven-article collection that details the NCCC’s comprehensive recommendations to Congress.
And in this episode of Diabetes Care “On Air,” co-hosts Alice Cheng and Michael Rickels are joined by commission members Dr. Bill Herman, Dr. Dean Schillinger, and Dr. Paul Conlin to learn more about the foundational report and the NCCC’s specific recommendations. (Full NCCC membership can be found here.) In addition, Dr. Neda Laiteerapong, a current associate editor of Diabetes Care, joined the team to discuss the key take-aways of the report for clinicians and health care teams.
We hope this special episode of Diabetes Care “On Air” inspires and motivates you to advocate for the critical recommendations outlined in the NCCC’s foundational report. Thank you for listening!
Mon, 20 Feb 2023 - 35min - 2 - Episode 2, February 2023 Diabetes Care "On Air"
Welcome to episode no. 2 (February 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Co-hosts Alice Cheng, MD, and Michael Rickels, MD, MS, open by discussing a recently launched initiative to feature artwork created by people with diabetes and/or people affected by diabetes on each cover of Diabetes Care. The February 2023 cover features a powerful image by Jaserah Chowdury. More information about this initiative and Jaserah’s piece can be found in Editor-in-Chief Steven Kahn’s editorial in the February issue.
Before launching into this episode’s interviews (see below), Alice and Mike note an important 5-article collection in the February issue on the National Clinical Care Commission Report to Congress on diabetes treatment and prevention. This openly accessible collection will be featured in the next episode of Diabetes Care “On Air”, so make sure to check it out in advance. On to the interviews:
At 2:39, Mike interviews Michael W. Schwartz of the University of Washington and James S. Krinsley of Columbia University. Drs. Schwartz and Krinsley are the lead authors of “Brain Glucose Sensing and the Problem of Relative Hypoglycemia.” This “Perspectives on Care” article, which can be freely accessed at https://doi.org/10.2337/dc22-1445, is one of the editor-selected feature articles in the February 2023 issue of Diabetes Care. At 20:58, Alice is joined by Kamlesh Khunti of the University of Leicester. Dr. Khunti is the lead author of “The Impact of the COVID-19 Pandemic on Ethnic Minority Groups With Diabetes,” another “Perspectives” article appearing in the February 2023 issue and openly accessible at https://doi.org/10.2337/dc21-2495. In the “Diabetes Care Rapid Exchange,” at 33:58, Alice and Mike wrap up the episode by reviewing other interesting articles in the February 2023 issue of Diabetes Care. Studies highlighted in this segment include:
X. Chen et al. Vitamin D Status, Vitamin D Receptor Polymorphisms, and Risk of Microvascular Complications Among Individuals With Type 2 Diabetes: A Prospective Study. https://doi.org/10.2337/dc22-0513 S.L. Liu et al. Effectiveness of Nonmydriatic Ultra-Widefield Retinal Imaging to Screen for Diabetic Eye Disease: A Randomized Controlled Trial (Clearsight). https://doi.org/10.2337/dc22-0713 J.-J. Liu et al. Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes. https://doi.org/10.2337/dc22-1611 J. Barbaresko et al. Dietary Factors and All-Cause Mortality in Individuals With Type 2 Diabetes: A Systematic Review and Meta-analysis of Prospective Observational Studies. https://doi.org/10.2337/dc22-1018 F.S. Malik et al. Prevalence and Predictors of Household Food Insecurity and Supplemental Nutrition Assistance Program Use in Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study. https://doi.org/10.2337/dc21-0790More information about Diabetes Care can be found at diabetesjournals.org/care.
Mon, 06 Feb 2023 - 43min - 1 - Episode 1, January 2023: Welcome to Diabetes Care "On Air"!
“Diabetes Care On Air” is a new podcast produced by the American Diabetes Association to present the latest research published in Diabetes Care, the most influential journal devoted exclusively to clinical diabetes research. In each episode, co-hosts Alice Cheng, MD, and Michael Rickels, MD, MS, will interview key authors of editor-selected feature articles and will highlight the latest research presented in Diabetes Care. Join Alice and Mike as they explore the latest high-impact research and information on diabetes care, treatment, and prevention.
In this inaugural episode, Alice and Mike are first joined by the new editor of Diabetes Care, Dr. Steven Kahn (1:18). Steven shares his vision for the journal and discusses the new initiatives and features that the journal is launching in early 2023. (See Steven’s editorial in the January 2023 issue: https://doi.org/10.2337/dci22-0045.)
At 13:39, Alice interviews Nestoras Mathioudakis of Johns Hopkins University, the senior author of “Racial Disparities in Access and Use of Diabetes Technology Among Adult Patients With Type 1 Diabetes in a U.S. Academic Medical Center.” This study, which can be freely accessed at https://doi.org/10.2337/dc22-1055, is one of the editor-selected feature articles in the January 2023 issue of Diabetes Care.
At 26:45, Mike is joined by Patrik Smidtslund and Lena M. Thorn of the University of Helsinki. Patrik and Lena are the lead and senior authors, respectively, of “Prognosis After First-Ever Myocardial Infarction in Type 1 Diabetes Is Strongly Affected by Chronic Kidney Disease.” This study is also an editor-selected feature article in the January 2023 issue of Diabetes Care, and it can be freely accessed at
In the “Diabetes Care Rapid Exchange,” at 37:35, Alice and Mike wrap up the episode by discussing some of the other learnings in the January 2023 issue of Diabetes Care. Studies highlighted in this segment include:
SJ Cromer et al. Deficits and Disparities in Early Uptake of Glucagon-Like Peptide 1 Receptor Agonists and SGLT2i Among Medicare-Insured Adults Following a New Diagnosis of Cardiovascular Disease or Heart Failure. https://doi.org/10.2337/dc22-0383 McDermott et al. Etiology, Epidemiology, and Disparities in the Burden of Diabetic Foot Ulcers (Review Article). https://doi.org/10.2337/dci22-0043 H. Seok Lee et al. Sustained Low Income, Income Changes, and Risk of All-Cause Mortality in Individuals With Type 2 Diabetes: A Nationwide Population-Based Cohort Study. https://doi.org/10.2337/dc21-2305 DJ Selen et al. Gestational Glucose Intolerance and Risk of Future Diabetes. https://doi.org/10.2337/dc22-1390 M-R Pasqua et al. Low-Dose Empagliflozin as Adjunct to Hybrid Closed-Loop Insulin Therapy in Adults With Suboptimally Controlled Type 1 Diabetes: A Randomized Crossover Controlled Trial. https://doi.org/10.2337/dc22-0490 D. Hoon Lee at al. Long-term Weight Training and Mortality in U.S. Male Health Professionals With and Without Type 2 Diabetes. https://doi.org/10.2337/dc21-2420To learn more about Diabetes Care, please visit diabetesjournals.org/care. Thank you for listening!
Tue, 03 Jan 2023 - 44min
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