Psychopharmacology and Psychiatry Updates

In this episode, we explore the bidirectional relationship between psychiatric disorders and cardiovascular disease, discussing a groundbreaking study involving over 900,000 subjects. We ask: Can a mental health diagnosis increase your risk of heart disease?

Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the science behind the art of psychopharmacotherapy with Dr. David Mintz. We delve into how psychosocial factors, including the prescriber's approach, can significantly impact medication outcomes. Did you know that some psychiatrists achieve better results with placebos than others do with active medications?

Faculty: David Mintz, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the long-term effects of methylphenidate on sleep in children and adolescents with ADHD. Can stimulant medication actually improve sleep in ADHD patients? We dive into surprising research findings that challenge common assumptions about ADHD treatment and sleep disturbances.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the strategic use of natural medications in psychiatry, focusing on combination therapies for various mental health conditions. Dr. David Mischoulon discusses potential synergies between natural remedies and conventional drugs, as well as all-natural combinations. But how do we balance efficacy with safety when using these less-studied treatments?

Faculty: David Mischoulon, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the use of memantine in treating trichotillomania and skin picking disorder. Could this common Alzheimer's medication be the breakthrough we've been waiting for in managing body-focused repetitive behaviors? Dr. Bob Hudak discusses a promising study that offers new hope for patients struggling with these often-overlooked conditions.

Faculty: Robert Hudak, M.D. Host: Richard Seeber, M.D.

In this episode, we explore Ashwagandha, a versatile natural remedy in psychiatry. We discuss its potential applications in treating anxiety, depression, OCD, and other mental health disorders. Could this ancient herb be the key to managing treatment-resistant patients?

Faculty: David Mischoulon, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the controversial use of electroconvulsive therapy (ECT) in adolescents with severe depression and suicidality. We discuss a study examining ECT's effectiveness, factors influencing outcomes, and its potential as a treatment option. Is ECT a viable last resort for treatment-resistant depression in teens?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the potential uses of Cannabidiol (CBD) in psychiatric practice. We discuss its mechanisms, evidence for various disorders, and guidelines for safe use. Is CBD the next breakthrough in mental health treatment, or just another passing trend?

Faculty: David Mischoulon, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the use of medical cannabis in treating Parkinson's disease. We discuss a retrospective study that reveals promising results for both motor and non-motor symptoms. Could medical cannabis be the versatile solution we've been seeking for Parkinson's treatment?

Faculty: Gregory Pontone, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the potential of N-acetylcysteine (NAC) in treating mood disorders. We discuss its mechanism of action, clinical evidence for its use in depression and bipolar disorder, and its possible benefits for both adults and children. Could this natural compound revolutionize our approach to mood stabilization?

Faculty: David Mischoulon, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the potential use of probiotics in treating ADHD symptoms in children and adolescents. Could the gut microbiome hold the key to managing this complex neurodevelopmental disorder? We discuss a recent meta-analysis and its implications for future research and clinical practice.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the challenges and best practices for managing bipolar disorder during pregnancy. We discuss key medications, their risks and benefits, and the importance of individualized treatment plans. How do we balance maternal mental health with fetal safety when treating bipolar disorder in pregnant women?

Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D.

In this episode, we explore a recent study challenging the safety concerns surrounding haloperidol use in older patients post-surgery. We discuss its implications for managing delirium and compare it to other antipsychotics. Could haloperidol be the unsung hero in our psychopharmacological arsenal?

Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the use of atypical antipsychotics during pregnancy for women with bipolar disorder. We discuss recent research findings, potential risks, and the delicate balance between managing maternal mental health and fetal safety. How do clinicians approach this challenging clinical decision?

Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the use of risperidone in treating anorexia nervosa in children and adolescents. We discuss a groundbreaking study examining its efficacy and tolerability. Can atypical antipsychotics like risperidone offer hope for young anorexia patients, or are we still searching for effective pharmacological treatments?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the complexities of managing lithium during pregnancy for women with bipolar disorder. How do lithium levels change throughout pregnancy, and what monitoring is necessary? We discuss dosing strategies, fetal monitoring, and postpartum considerations to ensure the best outcomes for both mother and baby.

Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the revolutionary potential of daridorexant, a new dual orexin receptor antagonist (DORA) for treating chronic insomnia. We discuss its unique mechanism of action, efficacy, and implications for future insomnia treatment. Could this medication be the key to "turning off" wakefulness in stubborn cases of insomnia?

Faculty: Carlos H. Schenck, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the risks and benefits of using lithium during pregnancy for women with bipolar disorder. We discuss recent research on cardiac malformations and dose-dependent risks. Is the fear of lithium use in pregnancy justified by the latest evidence?

Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D.

In this episode, we explore a groundbreaking study on escitalopram's efficacy in treating generalized anxiety disorder in children and adolescents. We discuss its potential as the first FDA-approved medication for youth anxiety. How might this change our approach to pediatric anxiety treatment?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore psychodynamic psychopharmacology and its role in addressing treatment-resistant cases. We discuss how patient-doctor relationships, transference, and countertransference can impact medication effectiveness. How might your own unconscious biases influence your prescribing decisions?

Faculty: David Mintz, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the therapeutic potential of psychedelic compounds in psychiatry. We discuss their definition, mechanism of action, and potential uses in treating anxiety and depression. How might psychedelics reshape the future of psychopharmacology?

Faculty: Sidney LeFay, D.O. Host: Richard Seeber, M.D.

In this episode, we explore the concept of patient ambivalence in psychopharmacology. How can understanding a patient's conflicting feelings about treatment improve outcomes? We discuss strategies for recognizing and addressing ambivalence, and its impact on medication adherence and effectiveness.

Faculty: David Mintz, M.D. Host: Richard Seeber, M.D.

In this episode, we explore vaping cessation methods used by US adolescent e-cigarette users. We discuss a study analyzing the prevalence and effectiveness of various quitting strategies, considering factors like demographics and perception of harm. How can healthcare providers tailor their approach to help teens quit vaping?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore Psychodynamic Psychopharmacology, an innovative approach to treating medication-resistant patients. We discuss how psychological factors influence drug responses and learn techniques to enhance treatment outcomes. Could understanding the meaning patients attach to their medications be the key to unlocking treatment resistance?

Faculty: David Mintz, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the complex relationship between benzodiazepine use and suicide risk, examining a groundbreaking French study that challenges our understanding of this connection. Is our go-to anxiety treatment potentially increasing suicide risk?

Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D.

In this episode, we explore how a psychodynamic approach can shed light on treatment-resistant cases. Can understanding a patient's psychological dynamics be the key to unlocking better outcomes?

Faculty: David Mintz, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the fascinating connection between ADHD, pain sensitivity, and methylphenidate treatment in children. Could methylphenidate help reduce pain sensitivity in pediatric ADHD patients?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we dive into the complex world of treating insomnia in patients with major depressive disorder. What's the best approach to help these patients find restful sleep and improve their mood? Join us as we explore a range of strategies, from medication to behavioral interventions.

Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the latest pharmacologic interventions for managing insomnia in patients with major depressive disorder. Can dual orexin receptor antagonists, melatonin agonists, and low-dose doxepin provide relief for those struggling with sleep? Join us as we discuss the advances in treating insomnia and depression.

Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the potential of fish oil as an adjunct to cognitive–behavioral therapy for treating depression in youth. Can this combination enhance treatment outcomes, or is cognitive–behavioral therapy alone just as effective? Join us as we dive into this intriguing study.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the use of benzodiazepines and nonbenzodiazepine hypnotics for managing insomnia in major depressive disorder. How do these medications work, and what are the key considerations when prescribing them? Join us as we navigate the complexities of pharmacologic interventions for insomnia.

Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the safety of antipsychotics in patients with liver disease. How can psychiatrists navigate the risk–benefit balance when treating medically complex individuals? Dr. Sydney LeFay discusses key insights from a recent review article, guiding antipsychotic selection and monitoring.

Faculty: Sydney LeFay, D.O. Host: Richard Seeber, M.D.

In this episode, we explore the complex relationship between insomnia and major depressive disorder. How does insomnia impact the course and treatment of depression? Join us as we dive into the neurobiology and clinical implications of this fascinating topic with expert Dr. Amit Chopra.

Faculty: Amit Chopra, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the long-term effects of ADHD medication use during pregnancy on children's development. Can continuing treatment pose risks, or is it safer than previously thought? Join us as we dive into a groundbreaking Danish study that sheds light on this critical question.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the growing evidence for nonpharmacologic therapies in managing fibromyalgia symptoms. Could a combination of exercise, cognitive–behavioral therapy, and integrative approaches, like acupuncture or yoga, be the key to better outcomes for patients resistant to traditional treatments?

Faculty: Daniel Clauw, M.D. Host: Richard Seeber, M.D.

In this episode, the editorial team of the Psychopharmacology Institute discusses 3 important topics presented at the APA Annual Meeting: Prescribing psychiatric medications during pregnancy, recent advances in clozapine treatment, and managing eating disorders, namely anorexia nervosa and bulimia nervosa. The episode covers the safety and dose adjustments for medications like SSRIs, lamotrigine, and lithium during pregnancy; early initiation and monitoring of clozapine; and effective treatments, including psychotherapy, olanzapine, and fluoxetine for eating disorders.

Hosts: Flavio Guzman, M.D., Paz Badia, M.D., and Lorena Rodriguez, M.D.

In this episode, we discuss a new study on maternal depression, antidepressant use, and pregnancy complications. Can antidepressants during pregnancy harm the baby? Dr. Lauren Osborne helps us weigh the risks and benefits.

Faculty: Lauren Osborne, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the most effective pharmacologic treatments for fibromyalgia, a complex nociplastic pain syndrome. Dr. Daniel Clauw shares his insights on the top drug classes for managing fibromyalgia and discusses why opioids should be avoided. Could the hyperactive endogenous opioid system in fibromyalgia patients explain the ineffectiveness of opioids?

Faculty: Daniel Claw, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the use of antipsychotic medication in treating children and adolescents with anorexia nervosa. Can these medications play a role in promoting weight gain and reducing comorbid symptoms? Or do the risks outweigh the potential benefits in this vulnerable population?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we dive into the diagnosis of fibromyalgia, a common nociplastic pain syndrome. We explore how to assess widespread pain and associated symptoms and how to understand fibromyalgia as a spectrum rather than a binary diagnosis. How can this nuanced approach help us tailor treatment strategies? 

Faculty: Daniel Clauw, M.D. Host: Richard Seeber, M.D.

In this episode, we delve into the potential for irreversible sexual dysfunction after SSRI use, based on a large-scale Israeli study. Could a few months or even days of antidepressant treatment lead to permanent erectile issues?

Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss the management of common adverse effects associated with clozapine treatment, including myocarditis, cardiomyopathy, tachycardia, orthostatic hypotension, and metabolic syndrome. How can clinicians mitigate these risks while optimizing treatment outcomes for patients with treatment-resistant schizophrenia? Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D.

In this episode, we explore relapse prevention strategies for youth with depression and anxiety disorders. Are there effective ways to reduce the risk and prolong the time to relapse? Dr. David Rosenberg discusses the findings of a recent meta-analysis and systematic review on this crucial topic.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we navigate the complexities of initiating and optimizing clozapine treatment for patients with treatment-resistant schizophrenia. How do you chart the course for successful clozapine therapy while managing side effects and drug interactions? Join us as Dr. Brian Miller shares his expertise and valuable psychopharmacology pearls.

Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss the prevalence of smoking among people with psychosis, based on recent findings from the PATH study. Dr. Oliver Freudenreich shares insights on how clinicians can prioritize smoking cessation in this population. How can we bridge the health outcome disparities faced by our patients with psychosis?

Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D.

In this episode, we delve into the use of clozapine for treatment-resistant psychosis and mood disorders. When should clinicians consider clozapine, and what do expert guidelines recommend? Dr. Brian Miller guides us through the evidence and best practices for utilizing this powerful but often underused medication.

Faculty: Brian Miller, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the role of lithium in treating pediatric bipolar disorder and conduct disorder. Is lithium a viable option for managing these complex conditions in children and adolescents, or are other medications more effective?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we explore real-world clinical cases demonstrating how broad-spectrum micronutrients can complement existing interventions for ADHD, emotional dysregulation, and mood instability. Can close monitoring and expert guidance optimize the integration of nutritional supplementation with pharmacologic treatments to create a harmonious, personalized approach?

Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss the groundbreaking FDA approval of zuranolone, the first oral medication specifically targeting postpartum depression. Could zuranolone's novel mechanism of action as an allopregnanolone agonist herald a new era of rapid-onset, targeted treatments for this debilitating condition affecting 1 in 8 new mothers?

Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D.

In this episode, we explore practical clinical tips for using broad-spectrum micronutrient supplements to treat mental health conditions. Can an individual's nutritional needs surpass population standards?

Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D.

In this episode, we examine whether first-trimester exposure to the antipsychotic olanzapine increases the risk of major fetal malformations. Does stopping medication abruptly also carry risks?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we delve into the safety considerations of using broad-spectrum micronutrient formulas in mental disorder treatment, mainly how these supplements can interact with other medications. Is it safe to use these formulas alongside anesthesia during surgery?

Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the potential of NSAIDs in delirium prevention. However, NSAIDs come with risks, such as GI bleeding or kidney injury. Can NSAIDs really help prevent delirium, and if so, how?

Faculty: Scott Beach, M.D. Host: Richard Seeber, M.D.

In this episode, we explore the unconventional yet promising treatment modality of using broad-spectrum micronutrient formulas in mental health care. We discuss the research and clinical trials that have been undertaken to test combinations of vitamins and minerals, focusing on their safety and efficacy. What are the potential side effects of using broad-spectrum micronutrient formulas?

Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss an insightful study by Strawn et al. that utilized a mega-analysis approach, combining data on over 900 MDD patients across lifespan treatment trials to elucidate differences in antidepressant treatment outcomes based on patient age. Does antidepressant efficacy differ across developmental stages—children, adolescents, and adults?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

What are some common signs that suggest a cancer patient may be developing delirium? In this episode, we explore the complex issue of delirium in advanced cancer patients. We discuss important considerations regarding medication management, the importance of distinguishing terminal from reversible delirium, and the role of antipsychotics and benzodiazepines in treatment.

Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss the treatment of agranulocytosis or neutropenia in patients on clozapine therapy, a rare yet serious scenario that clinicians may encounter. We delve into the possibility of rechallenging clozapine treatment after such an event and explore the use of colony-stimulating factors. What's the likelihood of agranulocytosis while prescribing clozapine long term?

Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D.

In this episode, we delve into the management of anxiety in cancer patients, including the effective psychotherapeutic interventions and pharmacologic options for treating anxiety in this vulnerable group. The episode also touches on the importance of cultural sensitivity and patient education when managing anxiety in cancer patients.

Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D.

In this podcast episode, Dr. David Rosenberg explores practical strategies to asess and manage common antidepressant side effects in the pediatric population. Get useful takeaways regarding activation, insomnia, withdrawal symptoms, and more.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this podcast episode, Jaroslava Salman, M.D., discusses the treatment options for depressed patients with cancer. Stay a step ahead in your practice with practical tips on which psychotherapies are helpful, which antidepressants to use and for how long, what to be mindful of, and even insights into prescribing stimulants.

Faculty: Jaroslava Salman, M.D. Host: Richard Seeber, M.D.

In this podcast episode, Dr. Vivien Burt delves into a study on brexanolone for women with postpartum depression, anxiety, and insomnia. Listen in and find out the effect and time frame of brexanolone on these symptoms.

Faculty: Vivien Burt, M.D. Host: Richard Seeber, M.D.

In this podcast, Dr. David Rosenberg offers practical insights into treatment optimization for youth with tic disorders. Listen in and find out which treatment modality takes precedence, which factors need to be considered, how long to use medication, and more.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this podcast, Dr. David Rosenberg expertly addresses the questions on what to do when your adolescent patient has ADHD but uses cannabis. Should you prescribe stiimulants or not? And what if they just want stimulants for better test scores? What do you do? Listen in as Dr. Rosenberg offers useful takeaways to help you with these (all too common) dilemmas.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this podcast, Dr. David Rosenberg delves into tic disorders and psychiatric comorbidities in youth. This includes ADHD, OCD, anxiety and depression, and disruptive behaviors. Jump in and listen to practical treatment options for these cases, and stay one step ahead in your clinical practice.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

CANMAT presents a spectrum approach to mixed states. In this podcast, Dr. Jim Phelps delves into this and the DSM-5 approach, where mixed states became a specifier that can be added to a diagnosis of unipolar depression, effectively creating a spectrum approach to the diagnosis of mixed mood disorders. So, what’s a clinician to do treatment-wise? Should we or should we not use antidepressants when 4 specific symptoms are present? Find the answer to these and other questions in this podcast.

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

In this podcast episode, Dr. David Rosenberg provides a much-needed understanding of tic disorders in children and adolescents. Listen in to learn what a typical course of this disorder could look like, why you may not need to substitute methylphenidate in these patients, what happens when patients supress tics, and much more.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this podcast, Dr. David Rosenberg explores a review on metformin for youth on SGAs. Is it effective in mitigating weight gain in this population? And more importantly, should you prescribe it ASAP? Listen in as Dr. Rosenberg answers these questions and others.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this podcast, Dr. Jim Phelps discusses the issue of diagnosing bipolar disorder within the framework of a mood spectrum. How bipolar should a patient be before switching treatment strategies? Listen in for tips and practical takeaways to answer this question and guide decision making.

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

In this podcast, Dr. Schenck discusses zolpidem-induced sleeping disorder and eating disorder. Listen and find out important tips and considerations, such as this being more common in females, alerting bed partners, being careful with zolpidem doses over 10 mg, and more.

Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D.

Cariprazine may be a good option for pediatric patients with schizophrenia and bipolar I disorder. Listen as Dr. Rosenberg summarizes study findings, which may broaden your options with children and adolescents.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

This podcast explores medication associated with sleepwalking and sleep driving, as well as recommendations for clinicians when prescribing them to patients.

Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D.

In this episode, we explore whether the olanzapine–samidorphan combination helps with psychosis while halting weight gain. We also look into the cost vs benefit of the combination as well as the metabolic side effects.

Faculty: James Phelps, M.D. Host: Richard Seeber, M.D.

Can melatonin reduce the risk of suicidality, bodily injuries, falls, and accidents in children and adolescents? In this episode, we explore a study that delves into this question. Discover how sleep disturbances impact young individuals' health, development, cognitive skills, emotional regulation, and behavior.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

Do you know what sleep-related eating disorder (SRED) is and how it intertwines sleep and eating pathologically? In this episode, we delve into an in-depth analysis of SRED, elucidating its diagnostic criteria, key characteristics of the diagnosis, and some intriguing aspects related to this disorder.

Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D.

This episode explores the controversial role of pimavanserin in treating psychosis in Parkinson's disease. How does it compare with quetiapine or clozapine? Sneak peek: All of these medications are effective, yet none distinctly surpasses the others.

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

Pediatric bipolar disorder treatment has evolved significantly since 2005, moving beyond lithium to several FDA-approved treatments. However, the challenges remain: How do we choose the first-line treatment? How can we mitigate and monitor side effects? In this episode, we discuss the latest practice treatment algorithms for pediatric bipolar disorder.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

Can pharmacogenomic testing improve the selection and dosing of antidepressants in patients with MDD? In this episode, we explore the findings of the PRIME Care trial and discuss the clinical significance of these tests. 

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss the role of broad-spectrum micronutrients (BSMs) in managing symptoms of ADHD. We examine the rationale behind opting for alternative therapies for this condition and dissect the outcomes of an RCT involving BSMs for ADHD. Could micronutrients provide a comprehensive strategy for treating ADHD, thereby enhancing overall mental wellness?

Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D.

Are you aware that a staggering 80% of ADHD patients report at least 1 side effect from their medication? In this episode, we discuss an analysis that seeks to answer an essential question: Can we predict medication nonadherence in adolescents and young adults with ADHD based on specific side effects?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

Did you know that your genes could affect how your brain processes vital nutrients? In this episode, we delve into fascinating research on micronutrient supplementation for mental disorders, such as ADHD. Discover how our genetic makeup might dictate our nutrient needs and how this can influence mental health outcomes.

Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D.

Could antipsychotic switching impact substance use in schizophrenia? In this episode, Dr. Jim Phelps explores the impact of antipsychotics on patients with schizophrenia and substance use disorder. He includes insights from national cohorts and clinical cases and delves into the potential effects of changing from risperidone to clozapine.

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

Dive into the fascinating world of nutrition's impact on mental health in our latest episode. We explore intriguing studies on the Mediterranean diet's potential to alleviate depressive symptoms. Can a shift in dietary habits truly improve mental health?

Faculty: Amelia Villagomez, M.D. Host: Richard Seeber, M.D.

In this episode, we explore a pressing problem in pediatric psychiatry: The disparities in the use of pharmacologic restraints. How can we address these biases in our healthcare system? What role do behavioral interventions play in reducing the need for these measures?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss the causes of clozapine-induced orthostasis. Although some patients may develop tolerance, it can limit titration and potentially obstruct patients from reaching the plasma level where they respond well to the medication. There are practical management strategies for orthostasis, including slow titration based on patient complaints and encouraging fluid intake, among others.

Faculty: Jonathan Meyer, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss the potential of lavender extract, Silexan, as an alternative treatment for anxiety and insomnia with Dr. Jim Phelps. Is it truly a promising solution free from dependency and withdrawal symptoms or just an effective placebo?

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

In this episode, we explore a common yet severe side effect of clozapine: Constipation. Why does this drug cause such drastic changes in colonic transit times, and how can we manage it effectively?

Faculty: Jonathan Meyer, M.D. Host: Richard Seeber, M.D.

In this episode, we discuss a comprehensive study on the potential cardiovascular risks of ADHD medication. Although these medications pose minimal risk for those without preexisting conditions, there seems to be an elevated risk for those with preexisting cardiovascular diseases. Should we confidently prescribe these medications?

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we delve into the problem of sialorrhea or excessive salivation in patients on clozapine. Why does this occur, and how can it be managed? Join us as Dr. Jonathan Meyer shares his expertise on this unique side effect.

Faculty: Jonathan Meyer, M.D. Host: Richard Seeber, M.D.

Can a simple lab test guide our choice of antidepressants? Explore the intriguing link between inflammation, measured by C-reactive protein (CRP) levels, and the effectiveness of certain antidepressants in this episode.

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

Could ketamine be the breakthrough we need in treating adolescent depression? Join us in this episode as we explore the potential of ketamine therapy and its rapid antidepressant effects. Also, learn how ketamine works, its safety profile, and why it's not quite ready for mainstream use in adolescents.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we dive into the puzzling case of a 67-year-old man experiencing violent moving nightmares. Is it rapid eye movement sleep behavior disorder, frequent and recurring nightmares, night terrors, PTSD, or another parasomnia? Tune in as we explore potential diagnoses with our expert Dr. Carlos Schenck.

Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D.

In this episode, we delve into a new horizon in the management of acute agitation. We discuss dexmedetomidine, a drug that's been around since 1999, recently reformulated into a sublingual film and FDA approved for treating agitation associated with schizophrenia or bipolar I or II disorder. We explore the results from a recent randomized trial and its potential for transforming psychiatric care. Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

In this episode, we dive into rapid eye movement sleep behavior disorder (RBD). Did you know that RBD's prevalence is on par with schizophrenia in middle-aged and older adults? Tune in as we explore the prevalence, assessment, and management of RBD, a condition that is not only a sleep disorder but a potential harbinger of severe neurological conditions, like Parkinson's Disease and Dementia with Lewy Bodies.

Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D.

In this episode, we dive deep into the effects of ADHD medication on anxiety and depressive symptoms in children and adolescents. Can these medications significantly exacerbate symptoms of anxiety or depression? Or do these symptoms arise more from the underlying condition of ADHD? We will delve into these critical questions and more through a thorough exploration of a comprehensive meta-analysis.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

In this episode, we delve deep into the diagnostic mysteries of RBD, the need for video polysomnography, and the mechanisms leading to RBD. Whether you are a veteran or new to the field, this episode promises to deepen your understanding of RBD.

Faculty: Carlos Schenck, M.D. Host: Richard Seeber, M.D.

Are we missing a vital piece in the schizophrenia treatment puzzle? In this episode, we explore the intriguing and controversial role of N-acetylcysteine (NAC) in schizophrenia. We dive deep into the evidence, the theories, and the ongoing debates about this seemingly simple over-the-counter supplement. Could NAC be the key to unlocking better outcomes for those with schizophrenia, or is it just another dead end?

Faculty: Jim Phelps, M.D. Host: Richard Seeber, M.D.

How can N-acetyl cysteine (NAC) and S-adenosyl methionine (SAMe) be effectively integrated into child and adolescent psychiatric treatment? In this episode, we dive deep into the world of NAC and SAMe and explore their potential applications, dosage, side effects, and more.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

How has the use of antipsychotics among children and adolescents been affected by the COVID-19 pandemic in the United States? In this episode, we delve into pandemic-induced trends in youth psychotropic prescriptions. Uncover how COVID-19 reshaped mental health services and psychopharmacology among young individuals.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.

Can nature’s remedies hold the key to mental well-being in our youth? In this episode, we delve into the potential uses and limitations of St. John’s wort and valerian in child and adolescent psychiatry and, most importantly, their evidence in treating psychiatric disorders in this population.

Faculty: David Rosenberg, M.D. Host: Richard Seeber, M.D.