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- 107 - Will It Sequence? Synthetic DNA
In this episode of Naked Genetics: How much of your personality is down to your DNA; we also look at synthetic DNA, and why we'd want to make it; plus, the spiders that turn one species of insect against its own kind... Like this podcast? Please help us by supporting the Naked Scientists
Wed, 09 Oct 2024 - 24min - 106 - Will It Sequence? 700-year-old DNA
In this episode of Naked Genetics: A mammoth discovery in ancient DNA structure; on the subject of ancient DNA, what can we sequence for a centuries old body? And, in quirks of evolution, the animal that drinks its own offspring's blood... Like this podcast? Please help us by supporting the Naked Scientists
Fri, 23 Aug 2024 - 21min - 105 - Will It Sequence: How effective is handwashing?
In this episode of Naked Genetics: The risk factors between schizophrenia and substance use disorder have had a fresh genetic examination; I put Illumina to the test and ask, 'what difference does washing our hands really make?' And, the the extraordinary way in which dung beetles use the night sky to orientate themselves... Like this podcast? Please help us by supporting the Naked Scientists
Tue, 16 Jul 2024 - 19min - 104 - Will It Sequence? What grows on your food?
In this episode of Naked Genetics: What the latest genetics research has to say about restless leg syndrome; I put Illumina to the test and ask, 'what really grows on our food?'; And, what makes a tardigrade so tough? Like this podcast? Please help us by supporting the Naked Scientists
Fri, 07 Jun 2024 - 24min - 103 - Will It Sequence? Hunting drug resistant bugs
In this month's edition of Naked Genetics: Why a genetic bottleneck created decades ago means some whales are in deep water; how wastewater is helping genetic sequencer track down deadly diseases; And, surf's up! how one beach dwelling creature is shredding the gnar in order to find food... Like this podcast? Please help us by supporting the Naked Scientists
Fri, 03 May 2024 - 22min - 102 - ADHD advantages, and mining microbiomes
This episode of Naked Genetics: has the evolutionary advantage to ADHD been uncovered? Also, We look at the microbiome of mining. And, the only vertebrate in the world that would thank you for saying that it looked like crap... Like this podcast? Please help us by supporting the Naked Scientists
Fri, 05 Apr 2024 - 22min - 101 - The roamin' Roman Empire, and Charles Darwin's love life
In this edition of Naked Genetics: The surprising findings of a roman empire diversity study; Are hybrid animals the way out of the biodiversity crisis? And, was charles darwin as romantic as he was scientifically brilliant? Like this podcast? Please help us by supporting the Naked Scientists
Wed, 28 Feb 2024 - 28min - 100 - The origin of Europe's MS disease, and South Pole sequencing
This episode of Naked Genetics, the origins of multiple sclerosis markers in northern Europe is revealed, and why it might have helped more people than it hindered; we also look at organisms surviving in Earth's most extreme conditions; and ask just why might a bunch of organisms be turning into crabs? Like this podcast? Please help us by supporting the Naked Scientists
Mon, 22 Jan 2024 - 27min - 99 - Testing for genetic diseases, and bats with big penises
This episode of Naked Genetics, we catch up with our genetics experts and look into the hot button genetics news; we look at how genetics affects our genes, and how genes affect our ageing; and, another extraordinary mating ritual in Quirks of Evolution... Like this podcast? Please help us by supporting the Naked Scientists
Fri, 15 Dec 2023 - 27min - 98 - Is vegetarianism genetic, and the penis-eating spider
This episode, we catch up with some of the more curious genetics news from the past month including how much Neanderthal is in you and how that affects your risk of disease. Also, we look at one of the most remarkable breeding strategies in the animal kingdom, a spider with two penises that eats one of them... Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Nov 2023 - 30min - 97 - COVID In Your Genes: The Risk Factors
Do our genes control how we respond to COVID? The question has been nagging at the world since the pandemic began. Now we have the answer - and it's yes. In this programme, geneticist Nathan Pearson uncovers the specific bits of DNA that make you more likely to catch coronavirus, as well as the bits that might make you sicker.... Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Apr 2021 - 29min - 96 - The Genes Who Came in for the Cold
How do we cope at the extremes of low temperature? Across the world, groups of people have historically made their home in icy and inhospitable landscapes... and even today, groups of thrill seekers push their bodies to the limits by going swimming in water close to freezing. In this month's programme, genes that help us handle - and even enjoy - being very cold. We've got two stories from the ancient ice, including the oldest ever DNA; plus, two modern genes found to be helping us out in interesting ways, whenever things get particularly chilly... Like this podcast? Please help us by supporting the Naked Scientists
Wed, 17 Mar 2021 - 29min - 95 - How To Tell Coronavirus Variants Apart
We're looking at the most critical variants of the coronavirus, and finding out how to tell whether they're flummoxing COVID vaccines. Plus: the cost of catching a serial killer; DNA with four strands instead of two; and a mutant fish whose fins have started turning into limbs! Like this podcast? Please help us by supporting the Naked Scientists
Wed, 24 Feb 2021 - 28min - 94 - Identical Twins: Not Identical?
Meet the small DNA differences that make their mark by existing in the magical period of early development. We'll hear how mutations in the very first stages of human embryos have bizarre consequences for identical twins; and how even earlier in the process, sperm use selfish genes to get ahead of the competition. Plus, an immunologist untangles mRNA COVID vaccines, from efficacy numbers to delayed booster shots... Like this podcast? Please help us by supporting the Naked Scientists
Fri, 15 Jan 2021 - 28min - 93 - RNA vaccines, privacy, and penguins
The first group of people in the world have received a 'genetic' vaccine against the coronavirus. What is it, and how does it work? Naked Scientist Chris Smith breaks it down and addresses your concerns. Plus, why some genes have to change rapidly just to stay the same; a new way to keep functional genetic information private; and three new species of penguin arrive on the scene... Like this podcast? Please help us by supporting the Naked Scientists
Thu, 17 Dec 2020 - 24min - 92 - Mink, Ivory, & a Disease Discovered Backwards
It's a regular Noah's Ark: from the coronavirus strains that have been spreading through minks, to a new DNA test that can track poached elephant ivory, to the genetics of a very useful - and very inbred - cat. Plus: scientists have discovered a brand new genetic disease, via an unlikely approach and an even unlikelier coincidence... Like this podcast? Please help us by supporting the Naked Scientists
Fri, 13 Nov 2020 - 27min - 91 - Slave Trade, Neanderthals, & COVID
This week: a risk factor for severe COVID that comes from Neanderthals; using genes to track the millions transported as slaves across the Atlantic; a doctor runs through the list of what coronavirus mutations are worth watching out for; and learning population genetics from a video game... Like this podcast? Please help us by supporting the Naked Scientists
Fri, 16 Oct 2020 - 28min - 90 - How To Survive Poison
This week, a message from Naked Scientists listener Loretta. "I'm curious if your show might cover some of the most interesting case studies of organisms developing tolerance to severe toxins, what genetic insight this gives us about adaptation and natural selection more broadly, and what some of the tradeoffs might be when evolving to have such tolerances." We're answering her question: how do animals - and even humans - eat poison, and get away with it? Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Sep 2020 - 29min - 89 - The Inner Lives of Birds
Tweet tweet! We're talking birds, and the incredible things they can do. Today we're spotlighting five of the coolest recent stories in bird genetics: hummingbirds powering their lightning-fast flight; a gene that controls migration; why males have different colours to females; how light pollution makes sparrows sicker; and the bird trapped for thousands of years under the Siberian ice... Like this podcast? Please help us by supporting the Naked Scientists
Wed, 19 Aug 2020 - 28min - 88 - Female Mosaicism: The Stronger Sex?
The same thing that makes the patchwork colours on a tortoiseshell cat, also - according to some - is why human females live longer, see colour better, and even more often survive the coronavirus. It's all thanks to having two X chromosomes. Females compensate by switching one of them off, and the result is two distinct groups of cells in the body, each preferring one of the two X's. Welcome to the weird world of female mosaicism... Like this podcast? Please help us by supporting the Naked Scientists
Wed, 15 Jul 2020 - 27min - 87 - Fermented foods: the real deal?
We take a look at the trendy world of fermented foods. Are they actually good for you? And if so, why? Plus, the latest genetics news: from bacteria that live inside cancer cells, to gene sequencing the dead sea scrolls... Like this podcast? Please help us by supporting the Naked Scientists
Mon, 15 Jun 2020 - 29min - 86 - ACE2: The Coronavirus Gateway
Are you one of the many people who take ACE inhibitors or ARBs to treat high blood pressure? Or to help with heart issues or diabetes? In the UK, this is about one in seven people, making these are some of the most common prescription drugs out there; and recently there have been worries that they might make a coronavirus infection worse. The link between the drugs and the virus is a molecule inside everyone's bodies called ACE2. On today's show, meet ACE2, the protein in the spotlight: the bastion of our defenses, that's become the very breach in our walls. Protector, turned betrayer... Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 May 2020 - 34min - 85 - The Coronavirus Mutation Situation
In this episode we're taking apart the tiny creature behind this global pandemic. From how looking at the genes of the coronavirus can help figure out the animal it comes from; to the exact ways it's spreading around the world; and even how a hidden mutation is threatening to lead vaccine-makers on a wild goose chase. Plus, Gins & Genes goes virtual; stay tuned to hear what's inside our guest's downstairs toilet... Like this podcast? Please help us by supporting the Naked Scientists
Wed, 15 Apr 2020 - 25min - 84 - Gene Genealogy & The Lost Family
One of the biggest tech booms of the past half decade has been direct to consumer DNA tests. The results come in the post, and with them come both answers and new questions: questions that tens of thousands of people now have to figure out how to ask. In this episode, a new book from journalist Libby Copeland about a sociological phenomenon and its effects, both grand and intimate... Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Mar 2020 - 24min - 83 - FOXG1 Syndrome: Fighting the Odds
Listener Vivek got in touch with a question about a rare genetic disease his son has, called FOXG1 Syndrone. In fact, it's so rare - and so newly-discovered - that only about six hundred people in the world have been diagnosed. Kids with FOXG1 have severe developmental delays; in Vivek's words, "everything that can go wrong - it's gone wrong with him." But the parents of FOXG1 children have been unusually tenacious when it comes to shaping the course of science. In this programme we meet those people blurring the line - metaphorically speaking - between the brain and the heart. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 20 Feb 2020 - 25min - 82 - The Fly Infest-agation
We got a Christmas present from listener Anna: a small plastic tube full of dead flies. They've recently been infesting the hospital where she works. She wants us to figure out what they are, and what caused the infestation. Can DNA crack the case? Plus, the return of Gins & Genes... Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Jan 2020 - 28min - 81 - African genetics and ethics
There are very few African studies in genetics. And on the whole, there is a big European bias in the field. In Europe there are resources of hundreds of thousands of individuals' data, like the UK Biobank, and so that's where most research take place. But there's a potential problem: the subtle differences in DNA may start to make a difference the more genetics is used to diagnose and treat diseases. All this is why a number of institutions have collaborated to survey thousands of people's genomes in rural Uganda. In this episode we cover the results of Africa's biggest ever genetics study;... Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Dec 2019 - 28min - 80 - What's in the water?
This month we're diving into the stuff that makes up two thirds of the Earth's surface. Can you use genetics to figure out what's in the water? We put the science to the test by making a geneticist guess our mystery fish. Plus, a story about whales and dolphins: what do you lose when you leave the land? Jump in, the water's fine. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Nov 2019 - 26min - 79 - Quadrillions: Sequencing the UK Biobank
Half a million genomes. That's how many the UK Biobank has, stored as blood samples in freezers up in Manchester. And in September 2019 they announced a project to sequence every single one of them. It's the obvious next step for the UK Biobank, the research study that began in 2006 and now consists of an enormous biological database: the personal and medical information of its 500,000 volunteers. That data is available to any researcher who applies to use it. But how is this, the biggest whole-genome sequencing project ever, going to work? Who's coughing up the hundreds of millions of pounds... Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Oct 2019 - 29min - 78 - The Dog Show
It's a doggy dog world... in this episode we're talking pugs, bulldogs, and French bulldogs. They've all been bred for flat faces, but their airways haven't shrunk alongside their skulls - meaning that they often struggle to breathe. How has this happened? After evolving for millions of years, why are their airways literally too big to fit into their heads? Have they been betrayed by their own genes? Naked Genetics is on the case. Plus, the origin of puppy dog eyes, and we sequence the genome of Bruce the black lab puppy... Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Sep 2019 - 30min - 77 - Mendel's Trick
Naked Genetics is back with new episodes every month! Today we're taking a step back. Where does genetics actually come from? How did we get to today's world of genome sequences and gene editing? It all started with a 19th-Century monk, working in his garden - but who was he really, and how did it take thirty years for him to be recognised? If you think you know this story, you might be surprised. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Aug 2019 - 30min - 76 - Decoding a Mammoth with George Church
Join Harvard DNA pioneer George Church and Chris Smith in conversation as they discuss gene cloning, DNA sequencing, decoding the mammoth genome, the risks posed by fossil viruses lurking in extinct genomes, the prospects of xenotransplantation and safety of gene therapy, and the risks of human CRISPR. The discussion was recorded on March 15th, live in front of a studio audience at the Hello Tomorrow Summit, in Paris, 2019... Like this podcast? Please help us by supporting the Naked Scientists
Sun, 24 Mar 2019 - 30min - 75 - The CRISPR baby controversy
In November, He Jiankui claimed that two genetically engineered children have been born. Did he really do it? And if so, what are the ramifications for the babies and for the field? Georgia Mills explores the controversy in a special edition of Naked Genetics. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 21 Dec 2018 - 28min - 74 - The future of forensic genetics
We're returning to the scene of the crime with another look at the latest techniques in the world of forensic genetics - can we really predict physical features or even ethnicity from your DNA, and what does this mean for our criminal justice system? Plus, is the 'CSI effect' real? And our gene of the month would be more at home at a rave than a lab. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Apr 2018 - 32min - 73 - A Festival of Genomics
We're off to a festival - but before you worry about where your tent and wellies are, it's the Festival of Genomics, held at a clean and dry conference centre in London rather than a muddy field full of rock bands and dodgy burgers. Plus, what does the public really think of genetic technology? And a fiery gene of the month. This is the Naked Genetics podcast for March 2018, brought to you in association with The Genetics Society. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Mar 2018 - 39min - 72 - Crime scene genes
It's CSI Naked Genetics, as we find out how genetic technology is used to solve crimes. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Feb 2018 - 31min - 71 - Back to the womb
We take a trip back to the womb and before, to find out about early development. Plus, the importance of placentas, why the age of your womb rather than your eggs matters, and a video game-inspired gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Jan 2018 - 34min - 70 - The future of genomic medicine
This month we're finding out how genetic advances are shaping the future of healthcare at the Genetics Society autumn meeting. Plus, signposts for bees and an operatic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Dec 2017 - 32min - 69 - Matchmaking at the zoo
This month we're off to the zoo to meet some lovelorn laughing thrushes, endangered snails, and the Cilla Black of Sumatran Tigers. Plus, a sneak preview of this year's Genetics Society JBS Haldane lecture, and a gene of the month that likes a tipple. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Nov 2017 - 35min - 68 - Evolution's luxury item
You're a mammal. I'm a mammal. Your pet cat or dog is a mammal, as are whales, lemurs, pandas and polar bears. But what exactly is a mammal, and what can our genes tell us about our evolution? Plus, school students take on the whipworm genome, the surprising genetic diversity of Papua New Guinea, and a gene of the month that's up all night. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Oct 2017 - 32min - 67 - Exposing the contents of your genes
Would you ever consider donating your genome to research? We meet a man who has, and find out why. Plus, we get our hands dirty in the search for new antibiotics, take a look at the ethics of human gene editing, and our gene of the month is getting ahead in life. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Sep 2017 - 31min - 66 - Store, write, edit
As scientists announce that they have used CRISPR technology to fix a faulty gene in a human embryo - not for the first time, but more accurately than ever before - we take a look at storing, writing and editing in DNA. Plus, our gene of the month is all ears. Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Aug 2017 - 34min - 65 - Genes and dementia
This month we're taking a look at the role that genes play in dementia, and finding out how researchers are using this knowledge to develop urgently-needed treatments. Plus, a big release of big data from the UK Biobank, and our gene of the month is an expert swordsman. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Jul 2017 - 29min - 64 - Bees, tress and 3-D genes
This month we're literally getting inside our genes, as we explore chromosomes through a 3-dimensional virtual reality art, music and science project. Plus, researchers are turning to bees, trees and more in search of new genetic systems, and our gene of the month has been around for a while. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Jun 2017 - 34min - 63 - Tackling tumours, curing cancer
This month we're zooming in on cancer, finding out how researchers are tackling tumours in unprecedented detail. Plus, our gene of the month is the guardian of your genome, rather than the galaxy. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 May 2017 - 44min - 62 - Battle of the sexes
We might joke about the battle of the sexes, but it turns out that this is actually true - at least for a hundred or so imprinted genes. Plus, what opossums can teach us about sex, reporting back from a very special scientific meeting, and a superhero-styled gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Apr 2017 - 31min - 61 - Putting genomics to work
The DNA sequencing revolution is providing ever more data about genomes from all kinds of species, from humans to bacteria. But how do we make sense of it all? Who gets their hands on it? And how do we use it to benefit patients? We meet the scientists developing new computer tools to analyse and democratise global genomics. Plus, how your partner's genes affect you - assuming you're a mouse - and a shrunken gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 15 Mar 2017 - 29min - 60 - Science and the single cell
Our bodies are made up of trillions of cells - but these aren't mere biological building blocks, as inert as bricks. They're constantly communicating and changing. So how do scientists measure this? Plus, you can now take part in an international survey about genetics knowledge, a GIANT study throws up new genes linked to height, and a romantic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Feb 2017 - 30min - 59 - Genes, laws and Brexit
We hear a lot about genetic modification and how it's being used to improve agriculture. But who decides whether modified crops can be grown? Do new gene editing techniques like CRISPR count as GM? And what happens to these regulations when the UK leaves the EU? Plus, our gene of the month comes with a tale behind it. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Jan 2017 - 29min - 58 - All human life is here
The story of human evolution is long and complicated, but the simple truth is - you're only here because your ancestors got lucky. Plus, we wind the clock back to the very start of human life, and discover how new research is pushing back the frontiers of human embryology. Plus a suitably festive gene of the month. This is the Naked Genetics podcast for December 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Dec 2016 - 29min - 57 - Searching for switches
This month we're delving into the junk in the genome - or, to put it more correctly - our non-coding DNA. Less than 2 per cent of the human genome contains protein-coding genes, so what does all the rest do? Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Nov 2016 - 30min - 56 - Testing, testing
We hear more than ever about the secrets hidden in our genes, from our risk of diseases to traits such as intelligence or even sporting ability. But can we really test for them? And just because we can, does that mean we should? Plus, an extremely popular - and extremely distracting - gene of the month. This is the Naked Genetics podcast for October 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Oct 2016 - 30min - 55 - Hello Dolly
This month we've got a special bonus-length podcast commemorating twenty years since the birth of Dolly the Sheep, the first mammal cloned from an adult cell. Her birth changed the scientific world, and led to the development of other transformative technologies. Plus, our gene of the month is keeping a straight face. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Sep 2016 - 41min - 54 - 40 years of selfishness
40 years ago Richard Dawkins' The Selfish Gene hit the shelves. We look back on how it changed the way many people think about genetics. Plus, linking nurture to nature, and a gigantic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Aug 2016 - 30min - 53 - Signal to noise
Building a baby is a complicated business, with millions of cells needing to work together. So how does it happen? Plus, how big data is making big strides in big genes, and our gene of the month is going round and round in circles. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Jul 2016 - 30min - 52 - Genes for all
Genes, genomes and genetic technology are playing increasingly important parts in our lives, industries, food and healthcare, and at a point in the not-too-distant future we're probably going to have to grapple with at least some of the contents of our DNA. But is the public really prepared to look inside its genes? Plus, the company aiming to bring molecular biology labs for all, and our gene of the month is crunchy on the outside. This is the Naked Genetics podcast for June 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Jun 2016 - 30min - 51 - Check your compatibility
You may not realise it, but your health, immune system and even love-life are governed by the particular set of so-called compatibility genes that you inherit. There are thousands of different variations in these genes, but why do we have such diversity and does it matter? Plus, we dig into the latest research on cancer genetics - how studying hundreds of tumour genomes might bring forward new breast cancer cures. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 May 2016 - 30min - 50 - What's in your genes?
As the costs of DNA analysis come down, we've seen the rise of direct-to-consumer genetic testing, allowing anyone to spit in a tube, pop it in the post and get a personalised readout direct to their inbox. But what do these tests actually reveal? Plus, how advertising execs can help us talk about genes, digging up the secrets in dogs genomes, and our gene of the month is totally legless. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Apr 2016 - 30min - 49 - Designer genes
The recent invention of powerful precision tools for editing the human genome - known as CRISPR, has opened up new worlds of possibilities for researchers seeking to understand how our genes work - and also those who want to permanently change the human genome for generations to come. But are we on the road to designer babies? Plus, we unpack the latest cancer breakthrough, and our gene of the month is making a terrible racket. Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Mar 2016 - 32min - 48 - Crazy for CRISPR
It's the hottest new biotechnology technique to hit the headlines since well, since ever. CRISPR is a precision set of genome editing tools enabling scientists to cut and paste together DNA in any organism, exactly how they want - and the implications for human health, and even humanity, are huge. Plus, linking genetics to lifestyle, and our gene of the month is black and white and very cute. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Feb 2016 - 30min - 47 - Naked Genetics 47
This month we bring you a bumper edition, packed full of all our favourite bits from the past four years. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Jan 2016 - 57min - 46 - Naked Genetics 46
Synthetic biology - engineering life - is set to revolutionise the world, but how? We'll be hearing about some of the most exciting applications for synthetic biology, and how it's being commercialised. Plus, our gene of the month has got itself all in a twist. Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Dec 2015 - 30min - 45 - Why don't elephants get cancer?
Animals like elephants and whales are made up of many more cells than a human, or a mouse, and they live far longer. Yet they hardly ever get cancer - and the big question is why? Plus, revolutions in genetics, and a magical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Nov 2015 - 30min - 44 - Engineering life
Imagine designing bacteria that can do whatever you want - from cleaning up oil spills to churning out the latest cancer treatments - ordering the biological parts online and building it in a couple of weeks. This is no longer the stuff of dreams, but the reality of synthetic biology. Plus, tracing European genes, how parasites manipulate our immune systems, I take part in a research project to find out if sociability is in my genes, and our gene of the month is looking for wedded bliss. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Oct 2015 - 30min - 43 - Hundreds and Thousands
When it comes to figuring out which genes and genetic variations are linked to particular traits and diseases, there's only one way to do it, and that's to go large, with cohort studies involving hundreds or even thousands of volunteers. We meet the Born In Bradford bunch, a Canadian cohort, and more than a few pairs of twins. Plus, oh my God, they killed our gene of the month! Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Sep 2015 - 30min - 42 - Mysterious methylation
There's more to life than the four letters of DNA, and our cells use a chemical tag known as DNA methylation to mark out certain parts of the genome, helping cells to remember what they're doing. And, as you might expect, it's pretty important. Plus, how your GCSE success could be encoded in your genes, an important molecular cause of autism identified, and an illuminating gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Aug 2015 - 30min - 41 - The wonderful world of epigenetics
Genes are the instructions that tell our cells what to do, but how do different types of cells know which genes to switch on or off at the right time? The solution lies in epigenetics - the molecular bells and whistles that act on top of our DNA to control gene activity. Plus, a new gene involved in severe obesity, and a mythical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Jul 2015 - 30min - 40 - Breeding a better cow
For centuries, breeders have been selecting plants and animals with desirable genetic traits. So how have some of these changes come about, and where will new genetic technologies take our food in the future? Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Jun 2015 - 30min - 39 - The story of maize
You may not realise it, but all the food you eat has been genetically altered over time by plant and animal breeders, capturing advantageous traits to grow more nutritious and easy-to-farm foods as efficiently and healthily as possible. Maize, or corn as it's often know, is a prime example of this change. Plus, is attractiveness to mosquitoes in your genes? And our gene of the month is small but significant. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 May 2015 - 30min - 38 - Patenting and preserving genes
There are few things in life as important as the food we eat, but making sure that we guard the genes in our crops for the future is just as important. Plus, we take a look at some of the intellectual property issues surrounding our food, learn squid's surprising secret, and our gene of the month might be a mayor. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Apr 2015 - 30min - 37 - A hundred thousand genomes
Over the past year the Government has unveiled an audacious programme under the banner of Genomics England, aiming to sequence the genomes of 100,000 people affected by cancer and rare genetic diseases. We take a look at some of the practical and ethical issues around the project. Plus, our gene of the month comes from the land of the forever young. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Mar 2015 - 30min - 36 - Genetically Modified plants
Genetically modified, or GM, crops are a hot topic. Some people are deeply suspicious of the technology while others see it as an effective and efficient way of generating bountiful, healthier harvests. Plus, purple tomatoes, a giant of a gene involved in heart disease, and what's in a name? We take a look at the naming of genes. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Feb 2015 - 30min - 35 - Clever mice and drunken flies
How do we learn complex tasks like playing the piano? Why can we remember things better after a good night's sleep? And why do people - and fruit flies - drink again after the hangover from hell? The answers are all in your genes. Plus, why large-scale searches for so-called "genes for schizophrenia" and other psychiatric diseases are turning out to be trickier than we thought, and a gene of the month with a touch of Scottish - or maybe Hollywood - spirit. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Jan 2015 - 30min - 34 - Searching for the engram
For many years scientists have been searching for the mysterious engram - the place in the brain where memories are kept. And thanks to advances in genetics and neurobiology, it looks like they're now getting close to finding it. Plus, contagious cancers in dogs and devils, and our gene of the month prefers the cold. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Dec 2014 - 30min - 33 - Targeting cancer genes
Every year in the UK more than 330,000 people are diagnosed with cancer. The good news is that more and more are surviving, and there's hope that the new generation of genetic research and targeted therapies will bring more cures in the future. But is cancer a cleverer enemy than we thought? Plus sealion genital cancers, and an over-excited gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Nov 2014 - 30min - 32 - Genes, ageing and metabolism
Could we one day be popping pills that tweak our metabolism and make us live longer? It's not as far off as you might think. Plus, the cow genome goes large, bat flu flies into focus, and an untidy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Oct 2014 - 30min - 31 - Long live our genes
Every day we get older, and whether you're desperately resisting the march of time, or embracing the ageing process, most of us would agree we want to live as long, healthy lives as possible. We'll be finding out how genetics research can help. Plus, making fingers with Alan Turing, growing lizard tails, and a long-lived gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Sep 2014 - 30min - 30 - Genes for sore eyes
From the beauty of a sunset or the ugliness of war to the smile on a loved one's face, our eyes bring us all kinds of information about the world around us. now researchers are working to develop new therapies for people who have lost this precious sense. Plus, smelling elephants, marmoset twins, and an all-seeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Aug 2014 - 30min - 29 - Issues for genetic testing
Whether we like it or not, we're heading further along the road of genetic testing, not just for single genes but for complex diseases and even ancestry. But can the results of gene tests change our behaviour? Plus colouring crows, electric eels, gluing chromosomes and a sketchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Jul 2014 - 30min - 28 - Gene therapy - Cystic fibrosis, blindness and more
Twenty years ago, gene therapy was a great hope for the future of medicine - directly tinkering with faulty genes to cure diseases, but progress has been slow. Now, things seem to be changing. Plus, silencing crickets, evolving brain and brawn, and a flowery gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Jun 2014 - 30min - 27 - Nature, nurture and wiring the brain
The more we understand about the genetic variations that affect our brains, the more questions are raised - for example, are we a product of nature or nurture, and what should we test for? Plus, why Y loss is bad for men, the usefulness of junk DNA, and a crunchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 May 2014 - 30min - 26 - Genes, depression and schizophrenia
Around one in four adults in the UK experiences mental health problems in any year, and mental illness is a major problem for sufferers, their loved ones, and society. It's becoming clear that genes are involved, but what do we actually know? Plus, artificial chromosomes, autism in the womb, and a toddling little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Apr 2014 - 30min - 25 - DNA damage and repair
Every second your DNA is under assault - not just from chemicals in our environment or food, but from the hurly-burly of life within our own cells. We'll be finding out how DNA gets damaged and repaired, and how researchers are exploiting this to find better treatments for cancer. Plus, liver from skin cells, DNA from ancient teeth, and a scary little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Mar 2014 - 30min - 24 - Smells like gene spirit
Smell is probably the oldest sense, hardwired right into our brains and closely linked to memory. Now researchers are trying to unravel the complex genetics that underpin it. Plus, contagious dog genital cancers, gene therapy for blindness, and a rather slimy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Feb 2014 - 30min - 23 - Now hear this
Hearing loss is distressing, whether it occurs later in life or in childhood. Now researchers are starting to unpick the genetic causes behind some of these problems. Plus, mice on drugs, stress and death, and a wobbly gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 Jan 2014 - 30min - 22 - Taking shape
Across the natural world, cells organise themselves into a wonderful array of shapes and structures. But how do they do this? Plus, building bones, plant sex in space, and a rather plump gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Dec 2013 - 30min - 21 - Come together
All living cells are made up of protein molecules - but how do they organise themselves into structures? Plus bee sex, tough mice, and a happily married gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Nov 2013 - 30min - 20 - Have a heart
The heart is a vital biological pump, beating around a billion times in a lifetime. But faulty genes can cause big problems. Plus, taming the tiger genome, solving citrus sickness, and our gene of the month is for all you hopeless romantics out there. Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Oct 2013 - 30min - 19 - Genes and genealogy
Who do you think you are? And is the answer in your genes? This month we're delving into genes and genealogy. Plus, putting an end to genetic determinism, and an ancient Egyptian gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sat, 14 Sep 2013 - 30min - 18 - Genes, infections and immunity
Why can some people stay fit as a fiddle, while other seem to catch every bug that's going? As you might expect, the answer lies in our genes. Plus, a multitude of mutant mice, the state of gene therapy for epilepsy, and an unseeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Aug 2013 - 30min - 17 - Let's talk about sex
Summer loving is in the air, so what better time to think about sex? But we're not going to get graphic - we're talking about the genetics of sex determination. Plus, why turkeys need a wingman, figuring out fingerprints, and a leggy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Jul 2013 - 30min - 16 - The future of fingerprinting
Our genes are our unique calling card, and DNA analysis has been used to solve crimes and resolve paternity disputes for decades. Now new genetic technology promises to revolutionise medicine. Plus, we meet the man who invented genetic fingerprinting, discuss Angelina Jolie's breasts, and savour a cheesy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Jun 2013 - 30min - 15 - Genomics - Hope or hype?
Genetic technology is expanding at a pace that few can keep up with, with huge amounts of data being generated every week. But is this explosion of information delivering meaningful advances for patients? Plus, how one scientist tracked down the gene fault behind his own disease, what sequencing the HeLa genome means for genetic privacy, and a Pythonesque gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Tue, 14 May 2013 - 30min - 14 - Doing the twist - packing DNA
Almost every single cell of your body is packed with more than two metres of DNA, containing your genes. But not only does it have to be packed up to fit in there, it also has to be organised and read. Plus, how genetic variations are linked to cancer risk,analysing dinosaur DNA, and an adventurous gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Apr 2013 - 30min - 13 - Beautiful otherness - autism genetics
It's thought that around one in a hundred children in the UK is somewhere on the autistic spectrum - a complex range of disorders that can be challenging to understand and live with. But recent advances in genetics are bringing hope for new therapies that might help. Plus, we look at the genes underlying Specific Language Impairment, find out why cancer has the X factor, and meet a hopeless-sounding gene of the month. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Mar 2013 - 30min - 12 - The wonderful world of RNA
You've probably heard of DNA, but what do you know about RNA? As well as being the molecule that shuttles information from our genes into our cells, it also plays a huge number of other roles in all cells, from bacteria and viruses to tiny worms, plants and humans. Plus we delve into quadruplex DNA, wonder about the wolf genome, speculate on skin colour and our gene of the month has a literary twist. Like this podcast? Please help us by supporting the Naked Scientists
Thu, 14 Feb 2013 - 30min - 11 - Fitting into your genes - the genetics of obesity
The gym is full, the pubs are empty - it can only be January, as a good proportion of the population resolves to shape up and lose weight. But are your efforts going to help you fit into your jeans (with a J), or are you just fighting against your genes (with a G)? Plus, we discuss how genes might jump between cows and snakes, and we've got gout, goats, giant pandas and a glass bottom boat.This is the Naked Genetics podcast for January 2013 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists
Mon, 14 Jan 2013 - 30min - 10 - Cancer genetics - When good cells go bad
Cancer is literally the enemy within us -it starts when our own cells get damaged and go rogue, multiplying out of control and spreading around body. But how can we use new genetic knowledge to beat it? Plus, decoding the wheat genome, finding out where birds came from, and our gene of the month is more art than science. Like this podcast? Please help us by supporting the Naked Scientists
Fri, 14 Dec 2012 - 30min - 9 - The genetics of germs
Our world - and our bodies - are teeming with bacteria. And although some of them are friendly, many of them are not. Plus, electrifying news about bacterial nanowires, cuddly koalas, and counting chromosomes, and our gene of the month is the mindblowing Mind Bomb. Like this podcast? Please help us by supporting the Naked Scientists
Wed, 14 Nov 2012 - 30min - 8 - Stop bugging me! The genetics of bedbugs and other insects
They suck your blood, hitch-hike on your luggage, and are a growing threat to the hotel industry. Bedbugs are a growing problem in the modern jet-set world, and scientists are using genetic techniques to try and understand why. Feeling itchy yet? Plus, we look at the genetics of some other annoying insects, get to the bottom of the recent controversy about junk DNA, and our gene of the month is none other than Superman and his weedier alter-ego Clark Kent. Like this podcast? Please help us by supporting the Naked Scientists
Sun, 14 Oct 2012 - 30min
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