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- 1239 - CARTA: How People Learned to Live in Cities with Michael Smith
The transition from Neolithic villages to early cities marked the greatest social transformation faced by our species before the Industrial Revolution. Our ancestors had to learn how to live in new settlements that had more people, higher densities, and more activities than had been known previously. The new adaptations to urban life involved changes in society and social processes, not just individual learning. Some changes came about through social interactions in a process called energized crowding; these include innovations in housing and the use of space, and the establishment of neighborhoods in cities. Other changes were driven by powerful new institutions, including formal governments and social classes. Do ancient cities—and they ways they responded to shocks—might hold useful insights for the development of urban adaptations to climate change today? Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40165]
Sat, 16 Nov 2024 - 18min - 1238 - The Deadly Trade in Oil and Gas
Oil and gas are the most traded commodities on the planet; they are also the chief causes of the most grievous harm our species has yet faced, the burgeoning climate crisis. Bill McKibben is the Schumann Distinguished Scholar at Middlebury College and a founder of Third Act, which organizes people over the age of 60 to work on climate and racial justice. He examines how the export of hydrocarbons, in particular, has become an enormous threat to efforts to rein in greenhouse gasses. It explores the role that America – the world’s biggest exporter of gas – plays in this ongoing catastrophe. And it looks at the role that non-tradeable commodities – sunshine and wind – play in easing this crisis. Series: "UC Berkeley Graduate Lectures" [Science] [Show ID: 40220]
Fri, 15 Nov 2024 - 1h 27min - 1237 - CARTA: Evolving the Construction-Ready Brain with Michael Arbib
Humans construct their physical worlds in part by designing and constructing new tools, habitations, and in due course diverse buildings and, in some cases, towns and cities and construct their symbolic worlds by putting words together to tell stories, articulate plans, tell lies, seek truth, and much more. This talk offers hypotheses that address a key question for anthropogeny: How did biological evolution yield humans with the “construction-ready brains” and bodies that made us capable of the cultural evolution that created the diversity of our mental and physical constructs that we know today? Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40161]
Mon, 11 Nov 2024 - 20min - 1236 - Explorations of Telomere Biology in the Context of Human Aging with Elizabeth Blackburn - Sanford Stem Cell Symposium 2024
Elizabeth Blackburn, Ph.D., examines the relationship between telomeres, cellular aging, and metabolic health, highlighting how telomere regulation differs between insulin-sensitive and insulin-resistant individuals. She discusses the effects of environmental factors—like glucose levels, stress hormones, and drugs—on telomere maintenance, which can disrupt cellular coordination and contribute to age-related diseases. Blackburn also shares insights from studies on hibernating lemurs, indicating that while their telomere health remains stable during metabolic slowdowns, it declines upon reactivation. Ultimately, she suggests that telomere maintenance could serve as a valuable biomarker for early signs of metabolic dysfunction, informing strategies for long-term health and resilience. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39944]
Fri, 8 Nov 2024 - 45min - 1235 - CARTA: Combinatorial Technology and the Emergence of the Built Environment with Larry Barham
This talk provides a deep time perspective for assessing the behavioural implications of the creation of the earliest known structure and the technologies used in its making. Evidence for the earliest structure appears relatively late, about 500,000 years ago in Zambia, and before the evolution of Homo sapiens. The next oldest structures were made by Neanderthals in Europe, 176,000 years ago. The site in Zambia preserves rare evidence for the shaping and fitting together of two tree trunks to make a stable framework. The process of combining parts to make a whole reflects a conceptually new approach to technology, one which remains central to everything we make as humans, including structures. Did the invention of combinatorial technology require the use of language to discuss and evaluate diverse ways to form new constructs and constructions? This question arises from the extended planning and expertise needed in the making of combinatorial tools. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40160]
Wed, 6 Nov 2024 - 20min - 1234 - Found in Translation: Development of a Cellular Therapy for Age-Related Macular Degeneration
Dennis O. Clegg, Ph.D., discusses treatments for age-related macular degeneration (AMD), a condition that causes vision loss. Clegg explains that while patients often report improved vision after receiving implants, objective tests don't always confirm this. He explores the potential differences in patients' responses based on genetics and disease progression. There is also an ongoing challenge in finding the best ways to reduce immune rejection of these treatments. New trials are underway to test implants in earlier stages of the disease, and researchers are looking at different strategies like localized immunosuppression. Additionally, some studies suggest that secretions from retinal cells may help preserve vision. Overall, there are many open questions, but advances in the field offer hope for better AMD treatments. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39459]
Mon, 4 Nov 2024 - 1h 12min - 1233 - CARTA: Bird Nests: Adaptive Variation on Innate Bauplans with Susan Healy
As distinct from the buildings of termites (interesting though these are), bird nests offer a more apropos point of comparison for human buildings – they are conducted by single vertebrate (or a few) and can be adapted to varied circumstances, with even a small effect of social learning. However, the basic Bauplan remains species-specific, unlike the creativity of the human architect. Since nonhuman primates lack interesting building skills, and so we suggest that bird nest construction may come to play a similar comparative role for architectural design. The static Bauplan of birds can be compared to the near-stasis of human tool use until the end of the Paleolithic, challenging us to assess the changes in human practice that unlocked an increasingly rapid process of cultural evolution. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40159]
Tue, 29 Oct 2024 - 18min - 1232 - CARTA: How Humans Came to Construct Their Worlds - Welcome and Opening Remarks
At a global level, Homo sapiens have reshaped the planet Earth to such an extent that we now talk of a new geological age, the Anthropocene. But each of us shapes our own worlds, physically, symbolically, and in the worlds of imagination. This symposium focuses especially on one form of construction, the construction of buildings, while stressing that such construction is ever shaped by diverse factors from landscape to culture and the construction of history embodied in it - and more. After a brief look at birds building their nests as an example of variation on a species-specific Bauplan, we sample a broad sweep of cultural evolution and niche construction from the earliest stone tools of Neanderthals and Homo sapiens through the Neolithic and the rise of cities to the formal and informal architecture of the present day. Finally, we explore the ways artificial intelligence may further change how humans construct their mental and physical worlds. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40169]
Tue, 29 Oct 2024 - 09min - 1231 - From Ground To Space: Studying Wicking Aboard The International Space Station
Our respiratory system provides oxygen to and removes carbon dioxide from the body. To function properly, the lungs need to fill up with fresh air upon inhalation. Unfortunately, for a variety of medical reasons, the amount of air that reaches the lungs can be insufficient, causing respiratory distress. Healthcare providers often administer liquid drugs in the trachea to ensure prompt relief. In this program, Emilie Dressaire, professor of mechanical engineering at UC Santa Barbara, discusses how the liquid drugs make their way down to the lungs. To answer open questions on drug delivery, her team has built an experimental system that is currently in Space. She presents the journey from UCSB to the International Space Station and shares the first results. Series: "GRIT Talks" [Science] [Show ID: 40087]
Sun, 27 Oct 2024 - 31min - 1230 - CARTA: Energy in the Balance with Barnabas Calder
Every building – from the Parthenon to the Great Mosque of Damascus to a typical Georgian house – was influenced by the energy available to its architects. This talk offers a historical perspective on a topic of great relevance today, the linkage of architecture and energy. It provides a useful complement to the non-urban perspective on ecology offered by the talk on “The indigenous architecture of Australia.” Architecture has been shaped in every era by our access to energy, from fire to farming to fossil fuels. The talk will discuss a range of buildings of the past fifteen thousand years from Uruk, via Ancient Rome and Victorian Liverpool, to China's booming megacities. If we are to avoid catastrophic climate change one important ingredients is to design beautiful but also intelligent buildings, and to retrofit - not demolish - those that remain. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40166]
Fri, 25 Oct 2024 - 20min - 1229 - Al for Security Security for Al
How secure are computers and how does artificial intelligence impact security? In this program, Christopher Kruegel, professor of computer science at UC Santa Barbara, explores two key questions related to security and artificial intelligence. First, how AI can help to improve security. For decades, security solutions have leveraged traditional machine learning models. Not surprisingly, recent advances in AI have opened up exciting new opportunities. Second, the security of AI systems themselves. Like any other software application, they can be exploited. Given their often-critical role, it is imperative to secure AI against attacks such as training data poisoning and adversarial inputs. Series: "GRIT Talks" [Science] [Show ID: 40086]
Mon, 21 Oct 2024 - 29min - 1228 - CARTA: From Cave to Architecture: Settling Down in Southwest Asia with Trevor Watkins
Human "place-making" began over a million years ago when early humans made the hearth the center of social life. By 450,000 years ago, they were using caves in southwest Asia and sometimes buried their dead beneath the floor, linking memory-making with place-making. Hunter-gatherers started settling seasonally around 24,000 years ago, with permanent stone settlements by 13,000 BCE. Large, co-resident communities became common in the Holocene. The Neolithic (9600-6000 BCE) saw major social, economic, and cultural innovations, including architecture, monuments, and symbolic systems. Neolithic societies, with their complex economic relations, proto-urban patterns, and ritualistic architecture, were the first "imagined communities," deeply tied to memory and social symbolism. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40163]
Sun, 20 Oct 2024 - 21min - 1227 - The Link Between Proteins Alzheimer’s and Parkinson’s Diseases
Proteins are large biomolecules that play critical roles in a host of cellular processes, from cell signaling to regulating the immune system. However, these life-giving proteins can form toxic aggregate species that have been linked to several neurodegenerative diseases, including Alzheimer’s Disease and Parkinson’s Disease. In this program, UC Santa Barbara professor Joan-Emma Shea discusses the tau protein as a model system to study neurodegeneration. Shea says this protein plays a functional role in stabilizing microtubules in brain cells, but it can also self-assemble to form amyloid fibrils (large “clumps” of Tau proteins). There are several neurodegenerative diseases linked to tau assembly, including Alzheimer’s Disease, Pick’s Disease, and chronic traumatic encephalopathy, and they are collectively known as tauopathies. Shea discusses new insights into tauopathies and targets for therapeutics. Series: "GRIT Talks" [Science] [Show ID: 40083]
Fri, 18 Oct 2024 - 27min - 1226 - Stem Cells and the Human Brain - Medicine Informing Novel Discoveries (MIND)
Explore the captivating realm of brain research at UC San Diego with Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A. Furnari and Khalessi delve into groundbreaking efforts to find new treatments for neurological conditions such as brain tumors, stroke, and brain injuries, bringing hope to patients and their families. Emphasizing ethics, innovation, and patient care, Furnari and Khalessi shed light on the challenges and successes in their quest to unravel the mysteries of the mind. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39723]
Wed, 16 Oct 2024 - 1h 04min - 1225 - CARTA: Lucy - Questions Answers and Closing Remarks
Lucy is one of the most famous fossils of all time. The discovery of this species had a major impact on the science of human origins and evolution. Why? What was that impact? The symposium speakers—each a prominent scientist in their field—will address this question and specifically discuss the discovery’s impact through time, starting with the first few years after the discovery, the lasting impact, and the state of the art in that research area today. We're celebrating the 50th anniversary of the discovery of the fossil skeleton “Lucy” with the aim of reigniting a global interest in how we “became human” and promoting the importance of connecting our human past to the global future on the planet. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39830]
Sun, 13 Oct 2024 - 1h 19min - 1224 - CARTA: Naming Lucy: Taxonomic Reasoning in Paleoanthropology with Andra Meneganzin
The discovery of a 3.2-million-year-old hominin skeleton named Lucy revolutionized human evolutionary studies. Her Linnean classification as Australopithecus afarensis sparked debates on taxonomy, highlighting the complexity of interpreting fossil evidence and shaping our understanding of hominin evolution. Lucy's systematics provide insights into the challenges of classifying early hominins, emphasizing how interpretations evolve with new evidence and knowledge. Comparing fossils with living ape taxa and extinct species helps infer evolutionary relationships, while considering temporal variation adds depth to our understanding. Lucy's case illustrates the ongoing debate on species classification in paleoanthropology and the critical role of evidence in shaping taxonomic hypotheses. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39837]
Fri, 11 Oct 2024 - 21min - 1223 - The Problem with Flood Insurance: Can Community Insurance Help?
Witness the resilience of Isleton, California, as they pioneer a groundbreaking, community-based flood insurance program aimed at fostering recovery and climate resilience. This initiative, led by UC Davis researchers, could revolutionize disaster preparedness, offering fast, flexible support post-flood and investing in long-term sustainability. Series: "UC Davis News" [Public Affairs] [Science] [Show ID: 40177]
Mon, 7 Oct 2024 - 03min - 1222 - Black Holes Spacetime and You
How much do we really know about the quantum nature of space and time, the origins of the universe itself, and its most mysterious phenomena - black holes? In this program, Clifford Johnson, professor of physics at UC Santa Barbara, explains why understanding the laws of physics helps explain how the world around us works, and can fuel our imaginations to dream, invent, and create. Johnson works to engage the general public with scientific ideas, through many media outlets, including the entertainment industry. He has been a science advisor for many movies and TV shows. Series: "GRIT Talks" [Science] [Show ID: 40084]
Wed, 9 Oct 2024 - 33min - 1221 - CARTA: Fifty Years Since Lucy’s Discovery: Advances in Scientific Knowledge on Human Origins and the Development of African Paleosciences with Yohannes Haile-Selassie
Lucy, discovered in 1974, revolutionized paleoanthropology, sparking interest in Africa's fossil-rich regions. This led to significant discoveries, pushing human origins records beyond six million years. Lucy's find prompted the establishment of research facilities in Africa, aiding local scholars' training. As we mark her 50th anniversary, we celebrate scientific progress and African research infrastructure while recognizing the need for further support to advance paleosciences in Africa. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39828]
Fri, 4 Oct 2024 - 23min - 1220 - Will Dam Removal Save Salmon on the Klamath River?
UC Davis researchers are exploring the effects of Klamath River dam removal on salmon populations and habitat restoration. Watch as we uncover the journey of salmon regaining access to 400 miles of historical spawning grounds. This study not only highlights the ecological benefits of river dam removal but also the cultural significance to Indigenous tribes. Series: "UC Davis News" [Science] [Show ID: 40179]
Mon, 30 Sep 2024 - 05min - 1219 - CARTA: The First Paleo-Rock Star: Is Lucy Still an Influencer? with Ann Gibbons
Lucy's 50-year legacy as a superstar in human evolution is undeniable. Yet, with newer, older fossils and a growing understanding of her ancient world, her status as our ancestor is questioned. This talk delves into how these discoveries reshape Lucy's narrative and our understanding of human evolution, likening her to a middle-aged celebrity facing new challengers. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39827]
Fri, 27 Sep 2024 - 21min - 1218 - Bioengineering a Kidney Chip for Better Safer and Faster Drug Development
Catherine Yeung, Pharm.D., Ph.D., M.P.H., discusses groundbreaking advancements in kidney-on-a-chip technology, emphasizing its potential to revolutionize human health. She delves into the role of environmental toxins, such as okra toxin A, microplastics, and plasticizers, in contributing to chronic kidney disease, particularly in regions with specific dietary practices. Yeung also addresses the challenges of replicating adult kidney cells from stem cells, which often retain a fetal phenotype, and underscores the value of stem cell-derived models for genetic manipulation and disease research. Additionally, she highlights the increased risk of kidney stones in astronauts post-spaceflight and the broader implications of organ-on-chip technology for studying therapies and diseases. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39458]
Wed, 25 Sep 2024 - 1h 11min - 1217 - Can Aging be Reversed? Stem Cells as a Key to Longevity
Curious about what happens to our cells as we age and how it affects our health? Shiri Gur-Cohen explores the role of tiny chemical tags on our DNA, like methylation, in influencing our healing and overall well-being. Gur-Cohen discusses how these tags might be shaped by our body's systems, such as the lymphatic system, and could even help repair or regenerate various parts of our body. Gur-Cohen proposes that uncovering these processes could lead to innovative ways to slow aging or boost our body’s natural healing capabilities. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39979]
Fri, 20 Sep 2024 - 27min - 1216 - California Communities Fighting Climate Change
Learn about the California Transformative Climate Communities Program by taking a journey with UCLA into three communities - Fresno, Ontario and Watts - leading comprehensive, collaborative, equitable, and innovative climate action that changes lives. [Science] [Show ID: 40150]
Wed, 18 Sep 2024 - 09min - 1215 - CARTA: Lucy African Heritage and ‘Paleodoms’ with Job Kibii
Since Lucy's 1974 discovery, African heritage management and paleoscientific research have evolved significantly. Partnerships with international organizations have supported these efforts, leading to flourishing research and collaborations. However, foreign researchers' access restrictions have hindered efficiency, innovation, collaboration, and diversity. Balancing access restrictions with scientific openness and responsible stewardship is crucial. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39826]
Fri, 13 Sep 2024 - 20min - 1214 - Spinal Cord Injury and Plasticity: Breathing After Injury
Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]
Wed, 11 Sep 2024 - 59min - 1213 - CARTA: Lucy’s Contribution: Understanding the Sequence of Steps Leading to Human Uniqueness with Kim Hill
Humans are a spectacular outlier among the millions of species of life on planet earth, with incredibly unique biological success. Slowly, scientists have begun to understand the traits that interacted to make us unique, such as cumulative culture, unique scales of cooperation, cognitive abilities, language, and a unique life history and mating system. However, the sequence of evolutionary events that led to our unique species was very much a mystery until the discovery of early bipedal hominins like the australopithecine, Lucy. Here, Kim Hill explains how we have learned so much about this improbable sequence and evolutionary pathway by discovering that early hominins were fully bipedal but still had small brains and little evidence for human mating and life history patterns or cumulative cultural evolution. Lucy helped us understand why the evolution of bipedality was a critical first step that led to an amazing evolutionary sequence that resulted in our spectacular outlier species. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39825]
Thu, 5 Sep 2024 - 20min - 1212 - Food Poisoning: Seafood and Bacteria
Human activities can increase levels of harmful microorganisms and pollutants in our water systems that have the potential to make us sick or threaten our food supply. Join microbial ecologist Dr. Sarah Allard as she presents emerging research from Scripps Oceanography that sheds light on seafood-related food borne illnesses. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Health and Medicine] [Science] [Show ID: 40082]
Mon, 2 Sep 2024 - 08min - 1211 - CARTA: Lucy's Legacy and the Past and Future of Primate Research with Melissa Emery Thompson
The connection between paleoanthropology and primatology began with Darwin's theory of human origins. Lucy's discovery challenged existing ideas, coinciding with observations of wild primates. This sparked a surge of research on primate behavior, enriching our understanding of human evolution. Despite behavior not fossilizing, studying living primates has deepened insights into ancestral lifestyles. By examining their social and ecological dynamics, researchers unravel the origins of complex behaviors like cooperation and culture, shedding light on human adaptations. This interdisciplinary approach has refined methods for studying social processes and their biological effects. Fifty years since Lucy's find, these tools continue to shape our understanding of human evolution and its relevance today. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39824]
Sat, 31 Aug 2024 - 19min - 1210 - Upgrading the Physiological Relevance of Human Brain Organoids
Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39456]
Tue, 27 Aug 2024 - 53min - 1209 - CARTA: How Did Lucy Become a Fossil? Investigating the Life Death and Preservation of a Famous Hominin with Anna Behrensmeyer
Lucy's 1974 discovery reshaped our understanding of early hominins. Geological studies dated her to 3.21 million years ago. Questions arose about her life and death, leading to investigations into her burial site and skeletal preservation. Found scattered on the surface, less than 40% of her skeleton was preserved. Some parts were articulated, indicating rapid burial, possibly by a river. Missing elements suggest scavenging and erosion. Debate surrounds her cause of death, with theories including a fall or predation. Bone fractures hint at trauma, but the exact circumstances remain unclear. Geological evidence disputes death by mudslide or flood. Tooth marks on her bones lack conclusive evidence of predation. These debates underline Lucy's enduring influence on paleoanthropology, sparking ongoing research into human evolution. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39823]
Fri, 23 Aug 2024 - 21min - 1208 - CARTA: How the Paleo Diet Worked for Lucy-and Led to Us with Jessica Thompson
Lucy's discovery in eastern Africa reshaped human origins research, highlighting our ancestors' diverse habitats. Initially thought vegetarians like chimpanzees, Lucy's group were adaptable omnivores. Recent findings suggest they used tools and hunted, challenging notions of early human development. This raises questions about when humanity's defining traits emerged. Did Lucy's dietary flexibility pave the way for our intelligence and tool use? Ongoing research aims to unravel these mysteries, using innovative methods to understand ancient diets and behaviors. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39822]
Fri, 16 Aug 2024 - 19min - 1207 - A Deep Look into Innovation and Equity in the AI Revolution
The AI revolution and other innovations are bolstering equitable, community-centered solutions to major societal issues from disease to wildfire, and technologies piloted at UC San Diego are laying the groundwork for a better future. UC San Diego’s experts are making the case for why public higher education institutions must be a driving force to ensure that ethical, people-centered technology is at the center of AI advancements, and why the U.S. must invest in infrastructure that ensures institutions like UC San Diego are able to work alongside industry and government to develop the next generation of AI technology and advocate for responsible development, regulation and investment. Series: "A Deep Look into the Future of Biology" [Humanities] [Science] [Education] [Show ID: 39709]
Sun, 18 Aug 2024 - 48min - 1206 - CARTA: Lucy and Evolution of Hand Dexterity and Tool Use with Tracy Kivell
The discovery of Lucy in 1974 gave insight into early hominin body form but lacked hand bones. Subsequent findings revealed Australopithecus afarensis hand morphology. New discoveries and research since then, including associated hand skeletons and archaeological evidence, have enhanced our understanding of hominin hand evolution and tool use. These advancements inform us about Lucy's tool-related abilities and dexterity, reshaping our interpretation of early human behavior. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39821]
Sat, 10 Aug 2024 - 19min - 1205 - CARTA: Lucy - Welcome and Opening Remarks
Lucy is one of the most famous fossils of all time. The discovery of this species had a major impact on the science of human origins and evolution. Why? What was that impact? The symposium speakers—each a prominent scientist in their field—will address this question and specifically discuss the discovery’s impact through time, starting with the first few years after the discovery, the lasting impact, and the state of the art in that research area today. We're celebrating the 50th anniversary of the discovery of the fossil skeleton “Lucy” with the aim of reigniting a global interest in how we “became human” and promoting the importance of connecting our human past to the global future on the planet. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39829]
Sat, 10 Aug 2024 - 03min - 1204 - Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem Cells
Benjamin Freedman, Ph.D., delves into the creation and functionality of kidney organoids. He discusses their focus on filtration over hormone functions, and answers intriguing questions about urine characterization and the necessity of organoid structures. Freedman explores the use of scaffolds for implants and ponders the philosophical implications of off-target cells in organoids, questioning whether these cells are a natural part of organ development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39455]
Mon, 5 Aug 2024 - 56min - 1203 - CARTA: What Was Lucy’s Impact on our Understanding of Bipedality Diet and Encephalization? with Carol Ward
Paleoanthropology is booming with discoveries, reshaping our understanding of human evolution. Lucy's 1974 find stands as a milestone, providing crucial insights into early hominins. Her species, Australopithecus afarensis, remains a key reference, revealing bipedalism and dietary adaptations. Recent findings suggest bipedality evolved from arboreal upright apes, not chimpanzee-like ancestors. Earlier australopiths show bipedality predates dietary changes, indicating walking aided dietary shifts. Some australopiths may have used stone tools before significant brain enlargement in Homo. Lucy's discovery led to an explosion of insights, showing she was part of a diverse group of bipedal apes in the mid-Pliocene. Lucy remains central to understanding human evolution, highlighting the importance of her discovery in shaping our knowledge. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39820]
Thu, 1 Aug 2024 - 19min - 1202 - Our Common Climate: Variability and Climate Change in the U.S. - Mexico Western Border Region
Please join us for the annual Keeling lecture in honor of Scripps Professor Charles David Keeling’s life and invaluable contributions to climate science and the Scripps Institution of Oceanography. Tereza Cavazos's will present an overview of relevant climate drivers shared in the US-Mexico western border region, as well as their possible changes and impacts. From extreme weather to droughts, from the monsoon rains to the jet stream and El Niño events, these variations see no artificial borders; however, adaptation to climate change poses major challenges particularly south of the border. Delays in finding feasible and equitable actions can have severe consequences for present and future generations. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 39650]
Wed, 31 Jul 2024 - 53min - 1201 - CARTA: The Savanna Hypothesis: Tracing an Enigmatic Idea Through Time with Kaye Reed
The savanna hypothesis suggests that early human ancestors evolved in open grasslands. Raymond Dart's 1925 discovery of Australopithecus africanus at Taung supported this idea. Lucy's 1974 discovery confirmed bipedalism in Australopithecus species but raised questions about their tree-dwelling habits. Studies since then have refined our understanding of ancient habitats and climates, showing that human evolution involved interactions with various environments, not just savannas. This requires a nuanced view of biomes, climates, and habitats to understand how early humans adapted and evolved. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39819]
Fri, 26 Jul 2024 - 15min - 1200 - CARTA: What Was Lucy’s Impact on Our Understanding of Other Australopith Relatives? with Bernard Wood
In 1974, understanding early human evolution was limited. Lucy's discovery provided insights into one early hominin, while her species, Australopithecus afarensis, revealed broader patterns. The abundance and quality of A. afarensis fossils help understand diversity, relationships, and the pace of evolution among hominins. Lucy's ilk sheds light on crucial topics such as taxic diversity, phylogenetic relationships, and the tempo of evolution within the hominin clade. They are key to unlocking the secrets of hominin evolutionary history before and after A. afarensis, offering valuable context for fossils found in southern and eastern Africa. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39818]
Mon, 22 Jul 2024 - 20min - 1199 - CARTA: Lucy's Children and Human Origins with Zeray Alemseged
Owing to its morphological and temporal placement, the Lucy species, Australopithecus afarensis, plays a pivotal role in our understanding of the human evolutionary career. Though many more fossil remains were recovered subsequent to Lucy’s discovery, the impact of the latter cannot be overstated not least its role as a trove of scientific data as well as its iconic nature. Research on Lucy and its species and continued fieldwork have inspired many research projects across Africa especially the Afar region of Ethiopia. One such project is the Dikika Research Project, which has discovered the earliest and most complete skeleton of a juvenile A. afarensis, dating back to 3.32 million years ago, filling in a major gap in our knowledge of the species. Here, I will briefly discuss what we learn from this skeleton about the Lucy species and what that implies to our knowledge of the many descendants of A. afarensis including our own species. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39817]
Thu, 18 Jul 2024 - 21min - 1198 - CARTA: The Discovery and Initial Interpretation of ‘Lucy’ as a Tipping-Point in Paleoanthropology with Ian Tattersall
The discovery of Lucy, a fossil from the 1970s, changed paleoanthropology. Before Lucy, scientists saw human ancestors as rough guides, not distinct species. This mindset dominated the interpretation of fossils. Lucy's discovery, representing a new species called Australopithecus afarensis, showed the need to define species clearly. The clash of old and new views was seen in a 1981 debate between Richard Leakey and Donald Johanson. Leakey's refusal to offer an alternative emphasized flaws in traditional practices. This marked a shift towards a better understanding of human origins and diversity, despite some scientists holding onto old ways. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39816]
Sat, 13 Jul 2024 - 17min - 1197 - A Closer Look at...Stem Cells and Human Longevity
Can we live not only longer but healthier lives? Robert A.J. Signer and Shiri Gur-Cohen explore how stem cell research may unlock the secrets of longevity. Signer discusses the critical role stem cells play in combating aging-related diseases, such as cancer and immune system decline, by boosting their regenerative abilities. His work on hematopoietic stem cells and “super stem cells,” which better manage cellular waste, shows promise for delaying aging and preventing disease. Dr. Shiri Gur-Cohen examines how vascular and lymphatic systems support stem cell health, revealing new strategies for enhancing longevity and reversing the effects of aging. Don’t miss this in-depth look at the future of aging and human health. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39869]
Thu, 11 Jul 2024 - 58min - 1196 - Capturing Late-Onset Neurodegeneration in Patient-Derived Neurons via Direct Reprogramming - Breaking News in Stem Cells
Andrew Yoo, Ph.D., provides insight into the ongoing research on neurodegeneration and neuronal reprogramming, highlighting the complexities and challenges in modeling and understanding these processes. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39454]
Tue, 9 Jul 2024 - 59min - 1195 - Building Fast and Reliable Machine Learning Systems with Yian Ma
Yian Ma, an assistant professor in the Halıcıoğlu Data Science Institute at UC San Diego talks about his research using scalable inference methods for credible machine learning. This involves designing Bayesian inference methods to quantify uncertainty in the predictions of complex models; understanding computational and statistical guarantees of inference algorithms; and leveraging these scalable algorithms to learn from time series data and perform sequential decision making tasks. Series: "Science Like Me" [Science] [Show ID: 39710]
Wed, 3 Jul 2024 - 28min - 1194 - CARTA: Before Lucy: The State of Knowledge on Human Origins with Donald Johanson
Since entering into the field of paleoanthropology in 1970, Donald Johanson has found a more focused and rigorous implementation of an expanded collaborative, multinational, transdisciplinary strategy of inquiry with the application of new theoretical and technical innovations that has resulted in a richer picture of our origins and a deeper understanding of how we became human—not only in Africa, but Eurasia as well. The discovery of Lucy 50 years ago provides an appropriate benchmark by which to contrast what we know in 2024 versus what we thought we knew prior to her discovery in 1974. Knowledge of the environment in which our ancestors lived and interacted and successfully navigated the challenges of survival is now coming into clearer focus. We are in a period of specialization, and it is imperative to embrace an integrated approach that melds biological and cultural evolution. Only in this way can we continue to provide a more far-reaching vision of our ancestry. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39815]
Tue, 2 Jul 2024 - 12min - 1193 - Understanding Atmospheric Rivers
Over the last two winter seasons atmospheric rivers have impacted California and the west with extreme precipitation and the cascading consequences of these events. The meteorology that causes atmospheric rivers is complex, but scientists at the Center for Western Weather and Water Extremes (CW3E) are working to help better predict them and understand what they mean for rainfall and snowfall across the state. Join CW3E Deputy Director Julie Kalansky to learn how scientists are researching the causes and consequences of these rivers in the sky, and are working to understand the impact of climate change on the frequency and intensity of these amazing weather phenomena. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 39649]
Mon, 24 Jun 2024 - 49min - 1191 - Precision Pediatrics: The Case for Genomic Sequencing in Newborn Screening
Almost every child born in the United States undergoes state-mandated newborn screening within the first 48 hours of life. The blood collected from a "heel stick" helps test for 80 different serious but treatable genetic disorders. These disorders can be either genetic (passed down in families) or congenital (present at birth). But... what if we could go further? What if we could test a newborn's entire genetic sequence? Pediatric geneticist Ingrid Holm discusses the risks, benefits, costs and ethics of genomic sequencing in newborns. Series: "Exploring Ethics" [Health and Medicine] [Science] [Show ID: 39266]
Mon, 10 Jun 2024 - 59min - 1190 - A Closer Look at...Stem Cells in Space
Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]
Mon, 3 Jun 2024 - 59min - 1189 - A Deep Look into the AI Revolution in Health and Medicine
As the influence of artificial intelligence expands through our daily lives, questions have emerged about how AI is being integrated in health and medicine. AI is now being implemented inside operating rooms, critical care units for patient evaluation and even within our homes to support those with disabilities. Along with the promise of AI comes ethical and social implications — which are crucial when applied in health care — including the representativeness of datasets used in algorithm training to avoid perpetuating health inequities. Four leading experts share their views on how society is navigating the new frontiers of artificial intelligence and the future of heath care. Series: "A Deep Look into the Future of Biology" [Health and Medicine] [Science] [Show ID: 39247]
Fri, 17 May 2024 - 1h 29min - 1188 - Effects of Astrocytic Circadian Clocks Disruption on Synaptic Pruning with Anca Pasca - Breaking News in Stem Cells
Medical advances have significantly improved the survival of preterm babies and term neonates with brain injuries due to environmental hypoxia or genetic causes. Anca Pasca, M.D., shares her work to understand the molecular mechanisms underlying neurodevelopmental disorders associated with fetal and neonatal brain injury. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39453]
Wed, 15 May 2024 - 55min - 1187 - My Journey Through Mathematics and Physics with Elliott Lieb 2023 Kyoto Prize Laureate in Basic Sciences
The 2023 Kyoto Prize Laureate in Basic Sciences, Professor Elliott Lieb presents snapshots of his seventy-year journey through the world of science, first as a would-be engineer, then as a physicist and later as a mathematician and a mathematical physicist. In many encounters with colleagues in different areas of research he learned that mathematics and a mathematical perspective can be pivotal in developing our thinking about physics. This fundamental connection between mathematics and physics was not always accepted at the beginning of my career, and it was even vigorously denied by some mathematicians and physicists. Lieb mentions some of his work to illustrate the value of mathematical physics for theoretical physics and to pure mathematics, the first being the Polaron bound found with K. Yamazaki in Kyoto in 1957. Another is the "ice problem", where he calculated the number of ways to color a chess board with only three colors so that neighboring squares never have the same color. Series: "Kyoto Prize Symposium" [Science] [Show ID: 39424]
Mon, 13 May 2024 - 56min - 1186 - California Against the Sea: Reflections on Communicating Sea Level Rise
Join Los Angeles Times environment reporter and author of the new book California Against the Sea Rosanna Xia and Scripps Institution of Oceanography coastal resilience specialist Laura Engeman for a discussion on communicating the science and impacts of sea-level rise and California’s changing relationship with the ocean. Engeman will also discuss how Scripps Oceanography is advancing science and technology to understand sea-level rise across California and beyond. Xia will also do a reading from the book and be on hand afterward to sign copies and meet audience members. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 39648]
Sun, 12 May 2024 - 59min - 1185 - A 60-Year Journey of Mammalian Fertilization with Ryuzo Yanagimachi 2023 Kyoto Prize Laureate in Advanced Technology
Born and raised in Hokkaido, Japan, Professor Ryuzo Yanagimachi, the 2023 Kyoto Prize Laureate in Basic Sciences, developed a love for nature. He became fascinated with the fertilization process of sea urchins. After studying the fertilization of fish and the life cycle of parasitic barnacles, he realized little was known about mammalian fertilization. He went on to train with Professor M.C. Chang at the Worcester Foundation for Experimental Biology, the father of mammalian in vitro fertilization and then started his own lab at the University of Hawai'i. His basic studies contributed to understanding the hidden capacity of sperm and eggs and overcoming human fertility problems. Professor Yanagimachi passed away in 2023 at the age of 95, just a few months before he was to receive his Kyoto Prize award. Dr. W. Steven Ward, Director of the Institute for Biogenesis Research at the University of Hawai’i will present Prof. Yanagimachi’s life and work. Series: "Kyoto Prize Symposium" [Health and Medicine] [Science] [Show ID: 39423]
Mon, 6 May 2024 - 1h 13min - 1184 - Stem Cells and Science in Space - Medicine Informing Novel Discoveries (MIND)
Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]
Sat, 4 May 2024 - 53min - 1183 - Stem Cells and Space: Global Astrobiotechnology Hub
Marking the one-year anniversary of the Global Astrobiotechnology Hub, an esteemed panel convenes to envision the future of space exploration and stem cell research. Central to their discussion is the imperative to enhance accessibility and expedite scientific inquiry in space. They advocate for a shift towards establishing regular access to space, enabling frequent dispatches of payloads and experiments. They highlight the pressing need to advance technology to democratize space research, opening doors for nontraditional researchers from industry, academia, and beyond. They emphasize the significance of scientist-astronauts who possess a nuanced understanding of research methodologies. Emphasizing the importance of public engagement, they underscore the need to disseminate research findings widely and mentor the upcoming generation of scientists. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39528]
Fri, 26 Apr 2024 - 54min - 1182 - Trustworthy AI in Healthcare: Whose Trust Needs to be Earned and How
As AI becomes more prevalent, many people are asking how it will impact health care. In this program, Dr. Ida Sim, Professor of Medicine and Computational Precision Health at UCSF and Cora Han, attorney and Chief Health Data Officer for University of California Health, discuss the issues surround health care and AI. Sim outlines the current thinking around the role of transparency and explainability in AI governance and oversight, and in earning and maintaining trust of various stakeholder communities. Han discusses AI governance efforts across UC Health, and state and federal efforts to develop resources for ensuring that AI systems are developed, integrated, and deployed in a trustworthy manner. Series: "UC Center Sacramento" [Health and Medicine] [Science] [Show ID: 39603]
Fri, 19 Apr 2024 - 50min - 1181 - AI and Computer Tutoring
Despite effective computer tutoring software, no adaptive tutoring system has been developed and open-sourced to the field. In this program, Zachary Pardos, Associate Professor of Education at UC Berkeley, talks about efforts to create more equitable access to adaptive learning technology with the introduction of the first open-source adaptive tutoring system based on Intelligent Tutoring System principles. This system, called Open Adaptive Tutor, and its adaptive textbook library, have been iteratively developed over three years. Pardos describes how this system can be used as a foundation for exploring integrations of generative AI and will share nascent results from their first evaluations of ChatGPT for content generation. Series: "UC Center Sacramento" [Science] [Education] [Show ID: 39583]
Tue, 9 Apr 2024 - 49min - 1180 - CARTA: Body Modification - Questions Answers and Closing Remarks
Permanent body modification is a unique and variable practice among humans, not observed in other mammals. Despite being costly and risky, it is regularly performed. Scientific understanding of this phenomenon is nascent, prompting a symposium aiming to assess current research status and prioritize questions for the next decade. The event brings together academics and industry practitioners, exploring historical and contemporary practices like tattooing, piercing, finger amputation, and cranial modification. The symposium aims to investigate the 'when' and 'where' of permanent body modification and understand the motivations behind it, considering personal justifications and scientific hypotheses. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39476]
Mon, 1 Apr 2024 - 1h 23min - 1179 - Cognitive Aging In The Oldest Old: Resilience And Risk Revealed
Claudia H. Kawas, M.D., addresses Alzheimer's disease and related conditions in older adults, noting the challenge of accurate diagnosis and the resemblance of other brain conditions to Alzheimer's. She introduces "resistance" and "resilience," explaining how some individuals remain cognitively intact despite brain changes. Kawas suggests declining dementia risk due to improved vascular health management, emphasizing the complexity of cognitive decline and the need for further research. Series: "Brain Channel" [Health and Medicine] [Science] [Show ID: 39532]
Fri, 29 Mar 2024 - 48min - 1178 - Hold Fast: Envisioning Climate Change through the Art and Science of our Local Giant Kelp Forests
Southern California’s giant kelp forests are ecosystems that are potentially vulnerable to the region’s warming waters, but unlike terrestrial forests, changes in these underwater ecosystems are largely invisible to most of us. Join biologist Mohammad Sedarat and artist Oriana Poindexter in an exploration of their collaboration on the aquarium’s new art exhibition, Hold Fast, an immersive journey through our local giant kelp forests. Learn how their unique perspectives are combined to provide visitors with insight into climate change through the lens of art. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 39556]
Mon, 25 Mar 2024 - 47min - 1177 - CARTA: Lip Plates in Ethiopia with Shauna LaTosky
In the literature on lip plates in Southern Ethiopia there has been a strong emphasis on their socio-cultural importance and little information about their biocultural significance. Shauna LaTosky proposes that cultural keystone species theory and cultural keystone place theory could provide a useful frameworks for understanding relationships between the agro-pastoralist Mursi of Southern Ethiopia and the plant species and places that are integral to maintaining their cultural bodily practices. Keystone designations are applied here to the indigenous fruit tree lomay (Ximenia americana) and special clay pits in recognition of their role in the success of permanent body modification practices such as the piercing and stretching of women’s lower lips, but also in the promotion of health, social well-being and a sustainable environment. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39470]
Fri, 22 Mar 2024 - 23min - 1176 - Beyond the Hype: Unraveling AI Myths Realities and Governance
How is AI reshaping industries and everyday life? And what are the ethical and societal implications of these changes? Brandie Nonnecke, Ph.D., Founding Director of the CITRIS Policy Lab at UC Berkeley, is navigating the intricate landscape of artificial intelligence, from its basic forms — such as narrow AI focused on specific tasks — to the aspirational concepts of generative AI that can be applied across various domains. In this program, Nonnecke gives a comprehensive understanding of AI, cutting through the hype to reveal its actual potential and limitations and preparing attendees for the nuanced reality of an AI-integrated future. Series: "UC Center Sacramento" [Science] [Show ID: 39566]
Mon, 18 Mar 2024 - 50min - 1175 - CARTA: The Recent History of Piercing Practices in Europe and North America with Paul King
Across continents, material evidence of body piercing jewelry abounds in the archeological record. However, the varying procedures and processes of piercing, healing, and stretching these wounds for adornment remains unfamiliar to most archeologists. This talk discusses the early self-experimentations that led to the development of the Euro-American body piercing industry. From the late 19th throughout the 20th centuries shared personal correspondence, illustrations, and photographs document the adaptations, innovations, successes, and failures that came to coalesce a current community’s collective knowledge. Understanding the processes of these secretive explorations provides insights into many of the cross-cultural practices of the past for which no clear records remain. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39474]
Fri, 15 Mar 2024 - 17min - 1174 - Learning to See Again with a Bionic Eye
What is bionic vision? Michael Beyeler, director of the Bionic Vision Lab and assistant professor of computer science at UC Santa Barbara, talks about how technology is being used to help people see again using bionic vision. Series: "GRIT Talks" [Science] [Show ID: 39443]
Mon, 11 Mar 2024 - 28min - 1173 - CARTA: Permanent Body Modification in Mesoamerica and Central America with Rosemary Joyce
Archaeological research in Mexico and Central America reveals insights into cultural practices, focusing on the history of body modification. Examining long-term patterns helps unravel motivations for adoption, change, and abandonment of these practices. The talk emphasizes how body modification histories in this region illuminate shared identities across linguistic, ethnic, and political boundaries, while also highlighting distinctions within regional traditions and individual societies. It suggests that indigenous societies viewed the human body as shaped by the community, challenging the notion of a universal boundary between the natural body and the social person. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39469]
Fri, 8 Mar 2024 - 18min - 1172 - CARTA: Female and Male Genital Modification with Ellen Gruenbaum
This talk offers an overview of the many forms of permanent genital modifications embedded in human cultures, where they occur, the reasons why, the archaeological investigations of origins, and future trends. Included are female clitoridectomy, excision, infibulation, and other practices that affect about five percent of females worldwide; and the male practices that affect one-third of males: circumcision, superincision, and subincision. Why have so many cultures invented and preserved these modifications as part of their valued heritage? Controversies abound: the current human rights opposition to all female practices is met with backlash, and others question the “justifications” for continuing male circumcision. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39471]
Fri, 1 Mar 2024 - 18min - 1171 - CARTA: Dental Ablation and Facial Piercing in Late Pleistocene Southwestern Asia and Africa with John Willman
Bioarchaeological studies of Pleistocene populations, examining practices like tooth ablation, facial piercing, and cranial modification, contribute to our understanding of social identities and population dynamics. Recent analyses of Ohalo II H2 in southwestern Asia and Oldupai Hominid 1 in Tanzania reveal dental evidence of intentional body modifications. Ohalo II H2 likely represents the earliest case of intentional incisor ablation in Southwest Asia, a common practice in Iberomaurusian and Natufian cultures. Oldupai Hominid 1 exhibits dental wear suggestive of facial piercings, a previously unknown practice in Late Pleistocene/Early Holocene East Africa. These early cases shed light on the cultural practices and social identities of Pleistocene populations. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39468]
Wed, 28 Feb 2024 - 19min - 1170 - CARTA: Permanent Body Modification: Archaeological and Early Historical Evidence with Brea McCauley
Today, permanent body modification (PBM) is very popular. Studies suggest that well over a billion living people have experienced one or more types of PBM. But what is the history of PBM? When did the different types originate? Were they invented recently, or do they have a long history? Did they appear simultaneously or at different times? This presentation examines evidence in non-human animals and extinct hominins, delving into early archaeological and historical records of seven main PBM types: tattooing, scarification, amputation, piercing, genital modification, dental modification, and bone shaping. Strong evidence supports human PBM for at least 15,000 years, with intriguing hints suggesting a history dating back as far as 80,000 years. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39467]
Fri, 23 Feb 2024 - 19min - 1169 - CARTA: A Multistep Evolutionary Scenario for the Culturalization of the Human Body with Francesco d'Errico
Our ability to adapt our bodies to culture has ancient origins. We suggest a timeline for how the culturalization of the human body evolved, starting around 500-300 thousand years ago. This timeline highlights key moments at 140 thousand years, 70 thousand years, and 45 thousand years, followed by a faster pace linked to the rise of production economies. The underlying idea is a gradual growth in the complexity of technologies shaping the body, along with increased time and effort invested in obtaining and transforming necessary materials. Simultaneously, the development of symbolic codes required the creation of specific cognitive functions and neural circuits, allowing for the decoding of intricate messages conveyed by these cultural practices. These practices likely became more intricate in terms of techniques, symbolic codes, and the involvement of specialized individuals over time to ensure their continuation and potential further development. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39466]
Mon, 19 Feb 2024 - 15min - 1168 - CARTA: The Recent History of Tattooing in Europe and North America with Matt Lodder
This talk presents a new account of the development of professional tattooing in Britain and America since the late 19th century. Research based exclusively in primary sources reveals that the story of what kickstarted the creation of commercial tattooing, and what sustained it, ultimately becomes intelligible as a small and interconnected network of transnational artists and – crucially – clients. These newly clarified networks problematise both the date and form of the customary notion of a “Tattoo Renaissance” in the 1970s and 80s. Moreover, this research presents a more diverse account of the transmission of design, technology and influence throughout Euro-American tattooing than had previously been understood both within the industry, and beyond. Research is drawn from Dr Lodder’s next book on the history of the modern Euro-American tattoo industry, due to be published in late 2024 with Yale University Press. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39473]
Sat, 17 Feb 2024 - 20min - 1167 - CARTA: Body Modification - Welcome and Opening Remarks
Permanent body modification is a unique and variable practice among humans, not observed in other mammals. Despite being costly and risky, it is regularly performed. Scientific understanding of this phenomenon is nascent, prompting a symposium aiming to assess current research status and prioritize questions for the next decade. The event brings together academics and industry practitioners, exploring historical and contemporary practices like tattooing, piercing, finger amputation, and cranial modification. The symposium aims to investigate the 'when' and 'where' of permanent body modification and understand the motivations behind it, considering personal justifications and scientific hypotheses. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39475]
Sat, 17 Feb 2024 - 10min - 1166 - The Impact of Bioengineering
Bioengineering, also known as biomedical engineering, is a multidisciplinary field that applies principles and methods of engineering, biology, and medicine to solve problems and develop technologies related to healthcare and biology. Bioengineers design and create a wide range of medical devices, pharmaceuticals, and therapeutic techniques. They work on projects such as artificial organs, medical imaging systems, drug delivery systems, tissue engineering, genetic engineering, and more. UC San Diego Jacobs School of Engineering Dean Al Pisano shares a conversation with the founding chair of the Department of Bioengineering, Dr. Shu Chien, and local bioengineering entrepreneur Dr. Gene Lay discussing the impact of bioengineering and how the field continues to drive innovation in medicine, improve patient outcomes, enhance quality of life, and is shaping the future of healthcare. [Science] [Show ID: 39399]
Fri, 16 Feb 2024 - 29min - 1165 - Machine Learning and Mathematics with Tristan Brugère
Tristan Brugère, a Ph.D. student in the Halıcıoğlu Data Science Institute at UC San Diego discusses his research at The Institute for Learning-enabled Optimization at Scale (TILOS). Specifically, how he is working on optimal transport and neural networks on graph generative models with applications to chip design. Series: "Science Like Me" [Science] [Show ID: 39342]
Tue, 13 Feb 2024 - 25min - 1164 - CARTA: Footbinding: A Gene-Culture Co-evolutionary Approach to a One Thousand Year Tradition with Ryan Nichols
This talk explores the 1000-year practice of "footbinding" in ethnically Han Chinese families, involving modifying young girls' feet by wrapping the toes under the sole, often resulting in broken toes. Two main hypotheses—Labor Market and Evolutionary Social Sciences—are considered for explaining the origins, maintenance, and cessation of footbinding. This talk presents evidence from autopsy results, medical examinations, anthropological records, interviews, and historical texts. It argues that evolutionary social and psychological principles related to hypergyny, mate guarding, parental competition, mate competition, and paternal uncertainty offer better explanations for the origins and maintenance of footbinding than labor market factors. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39472]
Sun, 11 Feb 2024 - 15min - 1163 - Can a New Chemical Industry Help the Environment?
How can we use raw materials to improve the environment? In this program, Susannah L. Scott, professor of chemistry at UC Santa Barbara, discusses how to efficiently use catalytic conversion of unconventional materials, such as biomass and synthetic polymers to create sustainable routes to renewable energy, fuels and chemicals. Series: "GRIT Talks" [Science] [Show ID: 39440]
Mon, 5 Feb 2024 - 28min - 1162 - Understanding the Red Tide Phenomenon
Join Professor Drew Lucas from Scripps Institution of Oceanography as he delves into the intriguing phenomenon of red tides. In this enlightening talk, you'll discover the behaviors of Lingulodinium polyedra, the primary organism behind these glowing marine events. Professor Lucas's groundbreaking research, featuring tools like an underwater microscope and a wave-powered profiling device, sheds light on the 2020 red tide's secrets. Gain insights into the complex swimming patterns of phytoplankton, their nutrient uptake strategies, and the resulting effects on marine ecosystems. This program offers an in-depth look at marine ecology and underscores the vital role of technological innovation in oceanographic research. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 39251]
Mon, 29 Jan 2024 - 1h 07min - 1161 - Dodging Day Zero: Drought Adaptation And Inequality In Cape Town
In the coming decades, individuals around the world must adapt to changing environmental conditions, often driven by climate change. Adaptation requires significant resources, prompting the question of whether existing economic and social inequities may be exacerbated when adaptation become accessible to some, but not others. Kyle Meng, associate professor of economics at UC Santa Barbara, explores what happens when one of the world’s most unequal cities experiences an unprecedented, nearly catastrophic environmental disaster. In 2017, following years of prolonged drought, the city of Cape Town announced an impending "Day Zero", at which point pipes would run dry. Using a variety of data sources, we show how households of different wealth levels adapted to Day Zero and discuss the long term implications of Day Zero for Cape Town's water use and public finances. Series: "GRIT Talks" [Science] [Agriculture] [Show ID: 39334]
Fri, 26 Jan 2024 - 29min - 1160 - Dissecting Human HSC Self-Renewal Mechanisms Throughout Ontogeny with Hanna Mikkola - Sanford Stem Cell Symposium 2023
Hanna Mikkola, M.D., Ph.D., shares her work in hematopoietic stem cells (HSCs) and their complex renewal process. Her research aims to unravel these cells' behavior in mice and humans, offering potential insights for future medical advancements. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39258]
Fri, 19 Jan 2024 - 33min - 1159 - Using AI to Build Better Wireless Networks with Tara Javidi
Tara Javidi, an Electrical and Computer Engineering professor at UC San Diego's Jacobs School of Engineering discusses her research in artificial intelligence and large scale wireless networks. Series: "Women in Science" [Science] [Show ID: 39163]
Mon, 15 Jan 2024 - 28min - 1158 - CARTA: CompAnth - Questions Answers and Closing Remarks
Comparative Anthropogeny (CompAnth) is the study of distinctly human traits and characteristics in the context of comparisons with our closest living relatives, the “great apes.” This symposium, the third of CARTA's CompAnth series, will present a collection of distinctive human traits, ranging from molecular, cellular, and anatomical biology to behavioral, societal, and cultural features. Given the large number of human traits for which no counterparts have yet been described in nature, the limitations of the comparative method will also be addressed and alternative approaches to the singularity that is the human phenomenon will be discussed. The goal is a better understanding of human origins and a full appreciation of our species’ planet altering effects. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39281]
Wed, 10 Jan 2024 - 33min - 1157 - Prenatal Inflammation Shapes Postnatal Immune Function by Reprogramming Fetal Hematopoiesis with Anna Beaudin - Sanford Stem Cell Symposium 2023
Anna Beaudin, Ph.D., delves into the intricacies of how prenatal inflammation impacts the immune system's blueprint, shaping its long-term function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39257]
Mon, 8 Jan 2024 - 37min - 1156 - The Importance of Considering Diversity in Autism Research and Practice with Brian Boyd - Autism Tree Project Foundation Global Neurodiversity Conference 2023
Brian A. Boyd, Ph.D., explores the health challenges faced by autistic individuals, especially those in diverse gender and sexual orientation groups. He highlights the impact of societal barriers on their mental and physical health. Boyd emphasizes the need for research considering race, income, and state healthcare laws. He discusses the importance of understanding intersectional identities and promoting inclusivity in autism research. Boyd stresses the significance of cultural humility, diverse representation, and systemic interventions to address disparities. He urges a comprehensive approach acknowledging the complexity of people's lives to improve the well-being of autistic individuals across diverse communities. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39169]
Wed, 3 Jan 2024 - 31min - 1155 - CARTA: Comparative Anthropogeny - Language: Uniqueness Out of the Ordinary with Eva Wittenberg
Human language is a strong contender for the title of most often named species-specific feature in the literature. But why is that? In this talk, Eva Wittenberg explores what we could mean by "human language", and how different conceptions of language inevitably lead to different answers about whether it is species-specific. While syntax is a central feature, it is only one of several, and the uniqueness of human language is that it arose from a combination of, perhaps, ordinary ingredients. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39277]
Mon, 1 Jan 2024 - 23min - 1154 - CARTA: CompAnth - Welcome and Opening Remarks
Comparative Anthropogeny (CompAnth) is the study of distinctly human traits and characteristics in the context of comparisons with our closest living relatives, the “great apes.” This symposium, the third of CARTA's CompAnth series, will present a collection of distinctive human traits, ranging from molecular, cellular, and anatomical biology to behavioral, societal, and cultural features. Given the large number of human traits for which no counterparts have yet been described in nature, the limitations of the comparative method will also be addressed and alternative approaches to the singularity that is the human phenomenon will be discussed. The goal is a better understanding of human origins and a full appreciation of our species’ planet altering effects. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39280]
Mon, 1 Jan 2024 - 11min - 1153 - A Deep Look into the AI Revolution
Artificial intelligence has captured the minds and curiosities of people and industries around the world. From commerce to education to medicine, the AI revolution offers promises and pitfalls in virtually every realm of society. You will hear four perspectives on the future of AI—from futuristic AI-based simulations for developing new medicines and vaccines; to navigating the frontiers of science with mind-boggling image analysis; to unprecedented explorations of how the brain works. You’ll also hear from the life sciences industry about how AI is pioneering innovation and new product development. Series: "A Deep Look into the Future of Biology" [Science] [Show ID: 39246]
Sat, 30 Dec 2023 - 1h 26min - 1152 - CARTA: Comparative Anthropogeny - Did Humans Evolve Concealed Ovulation? with Pascal Gagneux
Human ovulation lacks visible signs, unlike chimpanzees and bonobos with conspicuous genital swellings during fertility. This led to the concept of "concealed ovulation," seen as a human adaptation. Proposed reasons include encouraging paternal investment, confusing paternity to deter infanticide, enabling secret mating and female choice, and reducing female rivalry. Many non-human primates also have unsignaled ovulation. While self-reported human mating doesn't match ovulation, debates persist on subtle reproductive cycle influences. Some cultures use menstrual taboos to disclose fertility status. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39275]
Fri, 29 Dec 2023 - 23min - 1151 - Siblings of Neurodiversity - Autism Tree Project Foundation Global Neurodiversity Conference 2023
Join us for an eye-opening and heartfelt exploration of the intricate world surrounding autism, focusing on an often-overlooked perspective: the experiences of siblings. This compelling show delves deep into the lives of individuals whose stories are intricately woven with the journey of their autistic siblings, offering a poignant and illuminating portrayal of their challenges, triumphs, and the unbreakable bond that ties them together. Featuring: Giacomo Vivanti, Ph.D. Drexel University Jeniece Stewart-Dortch Special Needs Siblings Inc. Heather Nuske, Ph.D. University of Pennsylvania Eric Goll Empowering Ability Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39168]
Thu, 28 Dec 2023 - 58min - 1150 - CARTA: Comparative Anthropogeny - The Evolution of Shorter Inter-birth Intervals in Humans with Corinna Most
Life history theory suggests that inter-birth intervals (IBIs) depend on a trade-off between maternal investment in current and future offspring, influenced by the mother's energy and somatic maintenance. Normally, IBI aligns with maternal and infant body size, larger relative infant size leading to slower breeding. In contrast, humans have relatively shorter IBIs due to cooperative breeding, support from the social group. Some other species with cooperative behaviors also exhibit shorter IBIs, possibly aided by factors like meat-eating enabling early weaning around 2.5 million years ago in the Homo lineage. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39276]
Wed, 27 Dec 2023 - 19min - 1149 - CARTA: Comparative Anthropogeny - Insight into Human-specific Adaptations to High Altitude with Tatum Simonson
High-altitude adaptation stands out as one of the most notable examples of evolution within our species. Despite similar challenges of decreased oxygen availability, human groups on different continents have followed unique evolutionary trajectories. I will discuss how genomic, molecular, and physiological discoveries reveal key insights into human-specific evolutionary changes, examine comparative findings and limitations, and consider alternative approaches for understanding distinct facets of this extraordinary human phenomenon. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39274]
Sat, 23 Dec 2023 - 19min - 1148 - Imitation and Innovation in AI: What 4-Year-Olds Can Do and AI Can’t (Yet)
Young children’s learning may be an important model for artificial intelligence (AI). In this program, Alison Gopnik, professor of psychology and member of the Berkeley Artificial Intelligence Research (BAIR) Lab at UC Berkeley, says that comparing children and artificial agents in the same tasks and environments can help us understand the abilities of existing systems and create new ones. In particular, many current large data-supervised systems, such as large language models (LLMs), provide new ways to access information collected by past agents. However, they lack the kinds of exploration and innovation that are characteristic of children. New techniques may help to instantiate childlike curiosity, exploration and play in AI systems. This program is co-hosted with the UC Berkeley College of Computing, Data Science, and Society and the UC Berkeley Artificial Intelligence Research (BAIR) Lab. About the Series: CITRIS Research Exchange delivers fresh perspectives on information technology and society from distinguished academic, industry and civic leaders. Free and open to the public, these seminars feature leading voices on societal-scale research issues. Series: "Data Science Channel" [Science] [Show ID: 39351]
Fri, 22 Dec 2023 - 58min - 1147 - Rett Syndrome Patient-Derived Cortical Brain Organoids with Robert T. Fremeau Jr. - Autism Tree Project Foundation Global Neurodiversity Conference 2023
Robert T. Fremeau, Jr., Ph.D., delves into Rett syndrome, a complex neurological condition. His research with brain organoids unveils its origins and progression. Fremeau uncovers disease markers and innovative treatments, offering insight into the pursuit of breakthrough therapies. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39167]
Wed, 20 Dec 2023 - 38min - 1146 - CARTA: Comparative Anthropogeny - How Special are Our Neanderthal Genes? with Andrew Schork
The human genome contains segments of DNA with non-human origins. This introgressed genetic material is remnants of mating events between early modern humans and their archaic contemporaries (e.g., Neanderthals and Denisovans). In this talk, Andrew Schork will review the evidence for such genetic material, its consequences on phenotypic diversity in modern humans, and discuss if this process - archaic introgression - is typical among other great ape species. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39273]
Sat, 16 Dec 2023 - 17min - 1145 - AI Agents That Do What We Want
Researchers used to define objectives for artificial intelligence (AI) agents by hand, but with progress in optimization and reinforcement learning, it became obvious that it's too difficult to think of everything ahead of time and write it down. Instead, these days the objective is viewed as a hidden part of the state on which researchers can receive feedback or observations from humans — how they act and react, how they compare options, what they say. In this talk, Anca Dragan, Associate Professor of Electrical Engineering and Computer Sciences at UC Berkeley, discusses what this transition has achieved, what open challenges researchers still face and ideas for mitigating them. Dragan discusses applications in robotics and how the lessons there apply to virtual agents like large language models. Series: "Data Science Channel" [Science] [Show ID: 39350]
Fri, 15 Dec 2023 - 56min - 1144 - Decoding Autism: Unraveling Early Brain Development with Eric Courchesne - Autism Tree Project Foundation Global Neurodiversity Conference 2023
Eric Courchesne, Ph.D., explores autism, highlighting its complexity beyond the brain and its connection to genetics and brain development. He focuses on the "temporal cortex," a crucial area in autism research associated with gene regulation and social processing. Courchesne also shares how his personal journey with polio has informed his thinking on neurodiversity, research, and beating the odds. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39171]
Tue, 12 Dec 2023 - 42min - 1143 - Broader Impact: The Power of Positive Change - Exploring Ethics
Do scientists in the fields of genomics, materials research and other areas deemed important to society have an obligation to educate the general community about their research? Fleet Science Center's Scientist Engagement Manager Andrea Decker discusses the idea of broader impact, and how it affects a researcher's project to benefit society or advance desired societal outcomes. Series: "Exploring Ethics" [Science] [Show ID: 39264]
Mon, 11 Dec 2023 - 18min - 1142 - Stem Cells and Space - Sanford Stem Cell Symposium 2023
Experts discuss the immense potential of conducting experiments and manufacturing goods in space. They explore how this could enhance our understanding of health issues, unveil new discoveries, and produce innovative technology for use on Earth. The conversation encompasses collaborations between various industries and scientists, aiming to explore the distinct conditions in space to enhance life for all. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Jana Stoudemire, M.Bio. Axiom Space Alain Berinstain, Ph.D. Space Tango Marc Giulianotti, Ph.D. Sierra Space Kevin Engelbert, M.S.F. NASA Michael Roberts, Ph.D. CASIS Arun Sharma, Ph.D. Cedars Sinai Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39072]
Sat, 9 Dec 2023 - 55min - 1141 - CARTA: Comparative Anthropogeny - Social Complexity: Why Modern Humans are More Like Ants Than Chimpanzees with Mark Moffett
The most complex organizations in the living world beside those of humans are the colonies of ants. Mark Moffett will argue that points of comparison between sharply different organisms like ants and humans are exceptionally valuable to science, and indeed that modern humans are in many ways much more like certain ants than we are to our nearest relatives, the chimpanzees. He considers such issues as the role of individuality and group identity in ant societies; the advantages to ants of flat organizations without leaders or hierarchies; and what we can learn from ants with respect to direct and indirect communication, self-organization, job specialization, labor coordination, and global domination. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39272]
Fri, 8 Dec 2023 - 22min - 1140 - Neurodiverse Heroes - Autism Tree Project Foundation Global Neurodiversity Conference 2023
Join a diverse panel discussing neurodiversity's power and potential. They share personal stories, advocating acceptance, and envisioning a future where differences are strengths, not limitations. Discover the beauty of embracing unique perspectives and supporting each other in this enlightening conversation. Featuring: Garret Hoff Duke Law School Neurodivergent Students Association Jeff Snyder Neurodiverse Advocate Meagan McKenna Actress & Television Creator Andrew Arboe Autistic Self-Advocate & Public Speaker Serena DeJesus First Female Autistic MMA Fighter Thomas Dougherty Artist & Children's Book Author Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 39173]
Thu, 7 Dec 2023 - 1h 01min - 1139 - A Sense Of Direction In Insects
As sailors use constellations, wind direction, and current to determine their heading, so, too, do animals process diverse sensory information to set their course. Via this sensory processing, the animal’s brain develops a sense of direction, a prerequisite for navigating between points. To understand how the sense of direction is generated in the brain, we interrogate neurons in the brain of the fruit fly, Drosophila melanogaster. With numerous tools that allow observing the neural network structures and activities and perturbing them, we begin to understand how the brain transforms sensory information into a sense of direction. Series: "GRIT Talks" [Science] [Show ID: 39332]
Wed, 6 Dec 2023 - 31min
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