Science In Action

Many coronaviruses exist in nature that we don’t know much about. We don’t even know how and whether most of them might bind to human cells. Research published in Nature, by scientists at Wuhan and Washington Universities, describes a new way of designing novel receptor sites on cell cultures so that many types of coronavirus may now be cultured and studied to ascertain their risk to humans. Cambridge virologist Ravindra Gupta, who is not one of the authors, gives Science in Action his take on the risks versus the reward.

Dotted around the remains of Pompeii, visitors are often struck by the plaster casts of some of the victims’ dying moments. During recent restoration of several of these casts, scientists were able to extract DNA samples from bones which had previously been enveloped by plaster since their initial discovery. As Alissa Mittnik of the Max Planck Institute for Evolutionary Anthropology describes, some of the findings confound our previous narratives about their lives, relationships, and even their genders.

Rozenn Pineau, a plant evolutionary geneticist at the University of Chicago in Illinois, has been investigating the unique evolutionary history of the world's oldest (and biggest) tree - "Pando".

And finally, the oldest known tadpole is described from a 160 million year old Argentinian fossil by biologist Mariana Chuliver.

Presented by Roland Pease Produced by Alex Mansfield, with Eliane Glaser Production Coordination by Jana Bennett-Holesworth

(Image: Illustration of Covid-19 coronavirus binding to human cell. Credit: Kateryna Kon via Getty Images)

This week at least 150 people have been killed due to devastating flash flooding sweeping through areas of Valencia in Spain. Ana Camarasa Belmonte, Professor of Physical Geography at the University of Valencia, has been studying the flood patterns and hydrology of the area for years. Even she was astounded by the magnitude of the inundation. And, as Jess Neumann of Reading University in the UK tells Roland, part of the tragedy is that the effective communication of risk somehow relies on citizens being able to adequately imagine the almost unimaginable.

Ten years ago this week, Friederike Otto and colleagues founded the World Weather Attribution network. The network aims to provide quick analysis of climate change's impact on on extreme weather events. They have already found that the Spanish flooding was made more intense, and more likely, by our warming world. Earlier in the week they published a different analysis of the 10 most deadly, extreme-weather events of this century. They concluded that all 10 events were made more extreme or more likely by climate change, and that these 10 events alone account for some 570,000 deaths.

In the US, Scientists have tested the strain of H5N1 bird flu swabbed from the eye of an infected Texan farm worker. They found it to be both lethal and transmissible via the respiratory tract of mice and ferrets. It contains a mutation PB2-627K, common in avian viruses in mammalian cells, as Amie Eisfeld of the Universoity of Wisconsin-Madison explains.

Presented by Roland Pease Produced by Alex Mansfield Production Coordination by Jana Bennett-Holesworth

(Image: Aftermath of catastrophic floods in Spain's Valencia. Credit: Anadolu via Getty Images)

Betelgeuse, one of the brightest and most famous stars in the northern night sky, has varied in brightness with an elusive pattern ever since observations began. Many theories exist as to why it ebbs and flows with apparently two distinct rhythms – one shorter and another around 2000 days long.

But just recently two independent astronomical teams have unveiled papers suggesting the existence of an orbital companion circling the red giant. About the size of our own sun, the “Betelbuddy” may whizz round Betelgeuse, almost skimming its surface, every 2000 days. And why haven’t we seen the Betelbuddy before? Because, from here, it would be a million times fainter than Betelgeuse itself, as one of the authors, and long-time Betelgeuse watcher, Andrea Dupree of Harvard and Smithsonian Centre for Astrophysics explains.

Back here on earth, Omar Yaghi of Berkeley, University of California and colleagues have been designing a new material that can scrub carbon dioxide out of the air in minutes. They have patented this type of Covalent Organic Framework (COF) and are hoping to scale up production such that a few hundred tonnes deployed around our biggest cities could solve our CO2 crisis.

But then what do you do with all those gigatonnes of CO2? Maybe one thing would be to use solar power to convert it into plant food. Robert Jinkerson and colleagues describe in the journal Joule a proposal to transform global food production into “Electro-Agriculture”, growing plants, fungi and algae on acetate made from solar energy. Their proposal would also shrink the global footprint of farming to allow more natural habitat.

And finally, Michael Frachetti of Washington University in St Louis has published an archaeological survey of two lost conurbations in the mountains of southern Uzbekistan that he and colleagues rediscovered in the last few years. He argues that the scale and complexity of these dwelling, and their location over 2000m, way above normal agricultural altitude mean we need to reconsider these stops on what would have been the Silk Road, around 600-1000 CE, perhaps even pointing at a very early industrial economy.

Presenter: Roland Pease Producer: Alex Mansfield with Andrew Lewis

(Image: Orion sink to Kashimayarigadake. Credit: Getty)

The “dewilding” effects of fish farming and mariculture are in the spotlight this week. Farmed fish can impact marine ecosystems in several ways, and surprisingly one of those is the effect it has on consumer perceptions of the impact of eating farmed fish, as researchers Becca Franks of NYU and Laurie Sellars at Yale suggest.

Meanwhile, Manu Prakesh and colleagues at Stanford University in the US have found a remarkable plankton that can traverse the depths of the oceans by ballooning to five times its size, giving clues as to how an important carbon sink actually works. And Monika Bright at the University of Vienna has found animals and tubeworms living in the very rock below volcanic hydrothermal vents. Life finds a way…

…But not always. 445 million years ago the second worst mass extinction event wiped out countless species of life on earth. But why? This week astronomer Chrysa Avdellidou of Leicester University and colleagues say they have found the origin for a famous meteor event that also happened around that time.

Presenter: Roland Pease Producer: Alex Mansfield Production co-ordinator: Andrew Rhys Lewis

(Image: Aerial view of seagulls following a fishing trawler. Credit: Felix Cesare via Getty Images)

In the week the Nobel prizes for science are announced, Roland Pease takes a look at the stories behind the breakthroughs being recognized, and the themes that connect them. From the discovery of the tiny fragments of RNA that regulate our cells’ behaviour, via computer structures that resemble our brains, and harnessing those sorts of computers to design drugs and medicines, it has been one of the most interdisciplinary years for the prize panellists.

We hear from old students, recent colleagues, laureates and lab (and life) partners, including Rosalind “Candy” Lee and her husband Victor Ambros, of UMass Chan Medical School, US, Erika DeBenedictus of the Crick Institute, UK, and Dmitri Krotov of IBM Research.

Presented: Roland Pease Produced: Alex Mansfield Production co-ordinator: Andrew Rhys Lewis

(Photo: 3d rendering of RNA strands and lipid-based nanoparticles or liposome. Credit: Love Employee via Getty Images)

As we were putting the finishing touches to last week’s Science in Action, the US National Weather Service was warning of Hurricane Helene’s fast approach to the Florida coast – alerting people to ‘unsurvivable’ storm surges of up to 6 metres. But the category 4 storm powered, as forecast, far past the coast and into the rugged interior of Tennessee and the Carolinas. 150 billion tonnes of rainfall are estimated to have been dumped there, with devastating consequences for the towns and villages snuggled into the deep-cut valleys of the region. Bloomberg says the event could cost $160 billion. Extreme warmth in the Gulf of Mexico helped fuel the hurricane, and within a few days Berkeley climatologist Michael Wehner had computed the fingerprint of climate change on the event.

The journal Nature published this week a study estimating the true number of casualties of hurricanes like Helene – not just those registered in the immediate aftermath, deaths caused by the instant trauma, but those in the months, even years, that follow, because of the disruption to lives and infrastructure. Rachel Young of Stanford University was herself surprised by the scale of harm her calculations revealed.

At least the dams held in North Carolina during Helene, although the sight of torrents of water gushing down the protective spillways at the peak was fearsome to see. A year ago, the two dams upstream of the Libyan port Derna both failed during Storm Daniel – ripping out the heart of the city and claiming at least 6000 lives. We reported what we could at the time here on Science in Action. But a World Bank study on the disaster reported back to an international dam conference in India this week a more detailed investigation – though the fractious politics of Libya put constraints on their work. Climate change was a massive part – normal monthly September rain in the area is 1.5 mm – but over 200 mm, maybe 400, fell on the hills behind Derna the night of the 10th. But it was the report of independent engineer Ahmed Chraibi that interested Science in Action – on the condition of the two dams, one just on the edge of the city, the other larger one 15 km upstream. He confirmed these had been built, in the 70s, for flood protection not to store water, but were in a shocking state long before last year’s cataclysm.

You’ve not been paying attention here in the past 5 years if you haven’t learned how clever our immune system is in recognising viruses that invade our bodies. Different arms of the system like antibodies and white blood cells can take on the viruses directly, or kill infected cells to stop the infection spreading further. But it’s slow to respond to new infections, which is why our pharmacies also stock antivirals, small molecules which also lock onto components of viruses to stop them replicating. Too often though, they’re not as effective as we’d like. Flu antivirals for example work only if you catch the infection very early. So I was intrigued to read in the Proceedings of the National Academy this week of a new kind of drug that is like an antiviral, but gets the immune system to do the hard work. Imrul Shahria reckoned there are all kinds of antibodies and immune cells floating through our tissues not doing much, but that could be tricked into tackling flu infections – with a little molecular deception. He's effectively hacked the flu antiviral zanamivir which locks onto the neuraminidase protein – the N – of flu viruses, and given it immune superpowers.

Presenter: Roland Pease Producer: Alex Mansfield Production co-ordinator: Andrew Rhys Lewis

(Photo: Hurricane Helene causes massive flooding across swaths of western North Carolina. Credit: Melissa Sue Gerrits/Getty Images)

Valerie Trouet of the University of Arizona tells us how tree-ring data has been used to show how the jet stream has shaped extreme weather in Europe for centuries, influencing harvests, wildfires and epidemics.

Monash University’s Andy Tomkins discusses how, around 460 million years ago, the Earth was briefly encircled by a ring of dust – like Saturn is today, and that the resulting temporary astronomical shade may have cooled the planet. Andy proposes that this dust came from an asteroid which had a close encounter with our planet.

And the cell biology of choking on your drink with Laura Seeholzer from the University of California, San Francisco. Laura has won the 2024 Eppendorf & Science Prize for Neurobiology recognising her work on the discovery of how neuroendocrine cells protect our airways.

Presenter: Roland Pease Producer: Jonathan Blackwell Production co-ordinator: Andrew Rhys Lewis

(Photo: Members of the research team collected tree ring samples at various locations in Europe, including the Balkan region. Credit: Courtesy of Valerie Trouet)

The Sahara Desert has been experiencing unusually heavy rainfall due to an extratropical cyclone, causing flash floods in Morocco. We hear from Moshe Armon of the Hebrew University of Jerusalem.

A 485-million-year temperature record of Earth reveals Phanerozoic climate variability. Brian Huber of the Smithsonian National Museum of Natural History in Washington DC tells us more.

And Mary Lewis of Reading University discusses new research looking into what puberty was like for our ancestors towards the end of the last ice age. Teenagers from 25,000 years ago went through similar puberty stages as modern-day adolescents.

Presenter: Roland Pease Producer: Jonathan Blackwell Production co-ordinator: Andrew Rhys Lewis

(Photo: Moroccan municipal workers and members of Auxiliary Forces help drain a road in a flooded neighbourhood in the city of Ouarzazate. Credit: Abderahim Elbcir/AFP/Getty Images)

Nearly a year ago, the top of a mountain on the Greenland coast broke off and slid a thousand metres down into the Dickson Fjord. The impact created a tsunami that started two-hundred-metres-high and sloshed between the cliffs for nine days, producing a global seismic signal. But it was so remote, only now are the details becoming clear. We hear from Paula Koelemeijer, Wieter Boone and Søren Rysgaard.

The decline of the ancient inhabitants of Rapa Nui was unlikely to have been caused by a self-inflicted population collapse, thereby rejecting a contentious theory of ‘ecological suicide’. Anna-Sapfo Malaspinas of the University of Lausanne discusses her team’s findings which shed light on the population history of the island formerly known as Easter Island - one of the most remote inhabited places in the world, around 3,700 km west of South America and over 1,900 km east of the closest inhabited island.

A newly identified species of wasp that attacks and lays eggs inside an adult fly has been discovered by Logan Moore and colleagues from Mississippi State University. Around 200 species of parasitoid wasps that target the fruit fly have been discovered to date - they lay their eggs in living creatures - all of which have been shown to target their hosts during vulnerable stages, such as when larvae or pupae. Until now, no wasp that attacks and develops inside the adult stage of a fruit fly host has been described.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Andrew Rhys Lewis

(Image: Copernicus Sentinel Data (2023). Credit: European Space Agency)

A Chinese survey of diseased animals farmed for their fur – such as mink, foxes and raccoon dogs - has revealed high levels of concerning viruses, including coronaviruses and flu viruses, many of which appear to jump easily from species to species. John Pettersson of Uppsala University discusses the threat to us humans.

We learnt early on in the Covid-19 pandemic how important the genetic details of the virus were in tracking the spread and spotting new variants. The vaccines were designed from gene sequences shared electronically long before any biological samples became available. Virologist Emma Hodcroft has teamed up with researchers around the world to develop a new virus database, Pathoplexus, to speed up the sharing of gene sequences.

Mpox outbreaks are causing concerns in Central and West Africa - particularly in the Democratic Republic of the Congo. A smallpox vaccine has started arriving, giving some protection against mpox. But there’s good news this week in an experimental vaccine developed especially for mpox by Moderna – one of the companies that brought us the mRNA vaccines against Covid-19. Galit Alter, vice president of immunology research at Moderna, tells us animal tests show that it appears to be highly effective.

And we discuss embryonic eavesdropping with Francisco Ruiz-Raya of Glasgow University. In the yellow-legged-gull, baby bird embryos that have chattier parents tend to come out chattier themselves – and likely receive better care because of their enhanced communication.

Presenter: Roland Pease Producer: Jonathan Blackwell Production co-ordinator: Andrew Rhys Lewis

(Image: A mink in a mink farm in the hands of a man. Credit: Neznam/Getty Images)

In 1977 astronomers recorded a brief and strange radio transmission that looked like it perhaps had even come from an alien civilization. It was named the Wow! signal – because that’s what astronomer Jerry Ehman wrote on the computer printout upon its discovery. But now a team including Abel Méndez of the University of Puerto Rico at Arecibo have come up with an astrophysical hypothesis.

An oil tanker which was attacked by Yemen's Houthi rebels in the Red Sea last week is still on fire and may be leaking oil, the US Pentagon says. The talk now is of an agreement to salvage the tanker so a crisis may be avoided, but marine ecologist Carlos Duarte of the King Abdullah University of Science and Technology in Saudi Arabia explains how precious ecosystems are at risk.

A meta-analysis of Mediterranean Sea marine species reveals the profound impact of the Messinian Salinity Crisis. Konstantina Agiadi of the University of Vienna tells us how this drastic environmental event resulted in the almost complete evaporation of the Mediterranean Sea roughly 5.5 million years ago and how the resulting changes still influence ecosystems today.

Wildfires that swept across Canada last year are still burning in some parts. A new study has confirmed that they put into the atmosphere a vast amount of burned carbon, over half a billion tonnes. Only China, India and the USA emitted more fossil-fuel based carbon in that period. Brendan Byrne of NASA’s Jet Propulsion Laboratory has been using satellite-based observations to track the carbon release.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Andrew Rhys Lewis

(Image: The Wow! signal represented as "6EQUJ5". Credit: NAAPO)

Fishery assessment models – the “backbone” of fisheries management – overestimate the sustainability of the world’s fisheries, according to a study of 230 fisheries worldwide, and populations of many overfished species are in far worse condition than has been reported. We hear from Rainer Froese of GEOMAR - Helmholtz Centre for Ocean Research Kiel.

The lunar south pole contains evidence of ancient magma ocean. An analysis of lunar soil in the Moon’s southern high-latitude regions, performed using data from India’s Chandrayaan-3 mission, suggests the presence of remnants of a former ocean of magma. Roland speaks to Santosh Vadawale of India’s Physical Research Laboratory.

Stefanie Haustein of the School of Information Studies at Ottawa University discusses the article processing costs for open access of the journal publishing giants in science.

The risk of a banana apocalypse could be near, but biologists, including Li-Jun Ma of the University of Massachusetts, might have found a key to their survival. Bananas are facing functional extinction due to the disease Fusarium wilt of banana caused by a fungal pathogen. Discovery of molecular mechanisms used by the banana-destroying microbe brings hope.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Andrew Rhys Lewis

(Image: Fisherman emptying net full of fish into hold on trawler. Credit: Monty Rakusen via Getty Images)

In June this year there was the first detected occurrence of rabies in Cape fur seals, discovered after a rabies case in a dog that had been bitten by a seal. Professor Wanda Markotter, Director of the Centre for Viral Zoonoses at University of Pretoria, has been trying to work out how the virus spread into seals and how to keep people (and their pet dogs) safe.

The Japan Meteorological Agency issued a seismic “advisory” last week alerting local authorities and the public to a heightened risk of a massive, tsunami-generating earthquake on its southeast coast. Californian emergency manager and sociologist James Goltz, has been working with Japanese experts to evaluate a new dynamic alert system that they introduced after the great 2011 earthquake and tsunami which claimed up to 20,000 lives further north.

We hear from Professor Alan Jamieson from the depths of the Tonga Trench. He recently dived into it to see what weird and wonderful creatures he’d find there – but when he reached the bottom, he didn’t see what he expected...!

And Steven Goderis of the Free University of Brussels tells us about the Chicxulub impactor - the massive asteroid smacked into Earth off the Mexican coast causing the mass extinction event which wiped out the dinosaurs. He’s part of a paper in the journal Science, looking into the history of the impactor - revealing it was a rare carbonaceous asteroid from beyond Jupiter.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Andrew Rhys Lewis

(Image: Fighting Seals. Credit: Edwin Remsberg via Getty Images)

Cases of bird flu in farm workers in the US may be going underreported, due to supposed poor surveillance and lack of testing. We hear from Amy Maxmen of KFF Health News who has been reporting on a study in Texas.

We hear from Bradley Moore, Professor of Marine Chemical Biology at University of California, San Diego about marine algae using massive enzymes, dubbed PKZILLAs to biosynthesize fish-killing toxins.

BBC Science Correspondent Jonathan Amos gives us the latest on the two American astronauts who blasted off on a test mission to the International Space Station on 5 June, expecting to be back home in a matter of days. But the pair are still there, floating high above the Earth two months later - stuck indefinitely - now facing the sudden prospect of missing the summer entirely and even spending Christmas and New Year in space.

And sea lion camera crews are helping researchers explore previously unmapped ocean habitats in southern Australia. Nathan Angelakis of the University of Adelaide tells us about working with the animal camera operators and what we can learn from viewing their movements.

Presenter: Roland Pease Producer: Jonathan Blackwell Production co-ordinator: Jana Bennett-Holesworth

(Image: Young Farmer and Cows on Dairy Farm. Credit: EyeJoy via Getty Images)

Nasa's Perseverance Rover has found a fascinating rock on Mars that may indicate it hosted microbial life billions of years ago. Abigail Allwood, exobiologist at Nasa’s Jet Propulsion Lab, is on the team scrutinising the new Martian data.

And a couple of newly discovered, approximately 500 year old fossils from the ‘Cambrian explosion’ of complexity caught presenter Roland Pease’s eye this week. First Martin Smith from Durham University tells us about a tiny grub that is ancestor to worms, insects, spiders and crustaceans. Then Ma Xiaoya, who has positions at both Yunnan University in China and Exeter University in the UK, tells us about a spiny slug that was also discovered in a famous fossil site in China.

And the first sightings of the landscapes on the underside of the ice shelves that fringe Antarctica. These float atop the ocean around the frozen continent but effectively hold back the glaciers and ice sheets on the vast landmass. Their physical condition therefore is pretty critical in this warming world, Anna Wåhlin of Gothenburg University tells us.

Presenter: Roland Pease Producer: Jonathan Blackwell Production co-ordinator: Jana Bennett-Holesworth

(Photo: Nasa’s Perseverance Mars rover taking a selfie on Mars. Credit: Nasa/JPL-Caltech/MSSS)

The near extinction of vultures in India may be responsible for an additional half a million human deaths between 2000 and 2005. The widespread use of the painkiller diclofenac in herds of cattle, starting in 1994, led to a massive decline in vulture populations in India, as the drug is poisonous to them. We hear from environmental economist Anant Sudarshan of Warwick University.

Cooking like a Neanderthal - Mariana Nabais of the Catalan Institute of Human Paleoecology and Social Evolution has been replicating ancient butchering methods to learn how Neanderthals ate birds.

A faster test for sepsis – we hear from Sunghoon Kwon of Seoul National University about a new method for identifying the pathogens involved in sepsis cases. The test has the potential to reduce the turnaround times normally associated with developing treatments for infections and may improve patient outcomes.

And it seems we may have inherited some conversational habits from chimps – or rather from whatever came before us and chimps 6 million years ago. Cat Hobaiter of the School of Psychology and Neuroscience of St Andrews University and her colleagues have found that like humans, wild chimps engage in snappy, turn-taking conversations.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

(Image: World Wildlife Day - Gyps fulvus feeding on a buffalo carcass at Kaziranga National Park in Assam, India. Credit: Anuwar Hazarika/NurPhoto via Getty Images)

There’s an update from asteroid expert Patrick Michel about the European Space Agency’s Rapid Apophis Mission for Space Safety. The ESA have received permission to begin preparatory work for the planetary defence mission which will rendezvous with the asteroid Apophis, that will be passing by the Earth on Friday, April 13th 2029.

And in news from the Moon this week – a massive cave has been discovered on its surface that might be a window into the body’s sub-surface, and even a ready-made lunar base for future astronauts to use. The claim was made in Nature Astronomy by a team of Italian planetary scientists, and two experts in remote sensing who have been re-interpreting radar data from a NASA orbiter - Leonardo Carrer and Lorenzo Bruzzone from University of Trento in Italy. In the magazine Science, there’s a call for a re-doubling of efforts to tackle malaria in Africa as signs grow that a leading treatment, Artemisinin, is becoming less effective. Deus Ishengoma, a malaria expert with the Tanzanian National Institute for Medical Research, is worried, having seen the transformation Artemesinin made in the past.

Tiny solar-powered flying robots - an ultra-lightweight, solar-powered micro aerial vehicle capable of sustained flight is described in a paper published in Nature. Peng Jinzhe of the School of Energy and Power Engineering at Beihang University was part of the team behind the 8 millimetre robot.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

(Image: ESA’s Ramses mission to asteroid Apophis. Credit: The European Space Agency)

The 2024 north Atlantic hurricane season has started with a bang, with Hurricane Beryl traversing the whole ocean, and leaving a trail of destruction across the Caribbean, into Mexico and Texas. Presenter Roland Pease speaks to climate expert Michael Mann of Pennsylvania University about this hurricane season and the role of climate change.

And Roland speaks to Amie Eisfeld of the Influenza Research Institute at the University of Wisconsin–Madison, who has been looking at the infection and transmission of bovine H5N1 influenza (bird flu). The virus is shown to be transmitted through the milk of cows with bovine flu to mice and by intranasal exposure to mice and ferrets. The findings are published in Nature this week.

Ancient genomics: Neolithic farmers hit hard by the plague. Repeated outbreaks of plague may have contributed to the decline in Neolithic populations in Scandinavia, a Nature paper suggests. The analysis of ancient DNA from more than 100 individuals sheds light on the fate of these farmers around 5000 years ago. Roland speaks to geneticist Frederik Seersholm of the Lundbeck Foundation GeoGenetics Centre in Copenhagen.

And a cheap coating that can be painted easily onto the glass of greenhouses converts part of the sunlight spectrum into red light that should boost the rate at which plants grow. Roland joins the chemists and crop scientists to see if there really is a difference with tomatoes and strawberries.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

(Image: Hurricane Beryl batters northern Jamaica after killing 7 people in southeast Caribbean. Credit: Anadolu/Getty Images)

Science in Action is at the UK's Royal Society Summer Science Exhibition, hunting for dark matter, melting ancient ice, cleaning up disused mines and looking for the batteries of the future.

Presenter: Roland Pease Producer: Alex Mansfield Production Coordinator: Jana Bennett-Holesworth

(Image: Pile of used batteries ready for recycling. Credit: Mindful Media via Getty Images)

An injectable antiviral "PrEP" therapy that gives 100% protection against HIV infection. Trials among young women in South Africa and Uganda proved so effective, they were wound up early to accelerate its use. Linda-Gail Bekker of the Desmond Tutu HIV Foundation shares her excitement.

A new kind of gene therapy that uses the cell's own “epigenetic” mechanisms to silence troublesome portions of our DNA, tested against the prion protein responsible for some brain diseases. Jonathan Weissman led the research at the Whitehead Institute for Biomedical Research in Massachusetts.

Accelerated evolution is being tested in Matthew Nitschke’s labs in the Australian Institute for Marine Science to see if it can help protect natural corals against future global warming.

The amazing 4.200 km transatlantic flight of some Painted Lady butterflies – and the extraordinary detective work ecologist Gerard Talavera and team needed to prove it.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

(Image: HIV Vaccine Efficacy Trial Conducted In Uganda. Credit: Luke Dray / Stringer via Getty Images.)

How has China reached the top spot of scientific research so quickly? Science editor of The Economist, Ainslie Johnstone, gives us the CCPs grand, broad plans whilst senior reporter for Nature, Gemma Conroy, digs into the specifics of China’s future particle collider.

Also, Gene Kirtsky, who has been studying cicadas for 50 years, discusses the spectacle of the millions of insects which have been emerging across the USA this summer.

And Unexpected Elements' Marnie Chesterton gets close and personal with the stinkiest plant in the world at Kew Garden in London. Presenter: Roland Pease Producer: Ella Hubber Production co-ordinator: Jana Bennett-Holesworth

(Photo: Jiangmen Underground Neutrino Observatory under construction. Credit: VCG/Getty Images.)

With mice being the latest species to carry the disease, pandemic expert Rick Bright calls for stronger counter measures. “It’s like PTSD from February 2020” he says. The authorities in the USA are responding too slow to the spread of H5N1 bird flu through its dairy farms – even mice are carrying the virus now, and not enough is known of how it is evolving and whether humans are threatened. He talks Roland through the complex political and public health issues.

Child sacrifices in the Mayan empire a thousand years ago have been confirmed with DNA evidence from bones recovered in the 1960s from an underground pit. Some victims were twins, possibly indicating a brutal ritualistic re-enactment of an ancient myth involving divine twins. Geneticist Rodrigo Barquera describes the analysis.

Mature orchids perform a unique form of offspring-care, feeding tiny seedlings with nutrients via networks of thread-like fungal hyphae in the soil, according to experiments conducted at Sheffield University. Mycologist Katie Field has been delving into this underground sustenance network.

Geoscientists at the edge of the Arctic ocean are looking for ancient clues to the stability of the Atlantic circulation that brings critical warmth to Europe and the northern hemisphere. Could past changes help unravel the influence of global warming? Roland talks to Renata Lucchi in the control room of Research Vessel JOIDES Resolution.

Presenter: Roland Pease Producer: Alex Mansfield Production Co-ordinator: Jana Bennett-Holesworth

(Image: Mouse sitting on grain. Credit: SAEED KHAN/Getty Images)

The ‘origami’ superpowers of a single-celled pond hunter, it hunts by launching a neck-like proboscis that can extend more than 30 times its body length. Manu Prakash of Stanford University reveals the amazing mathematical mechanisms of the protist, Lacrymaria olor.

It’s a microbe-eat-microbe world out there, with bacteria waging constant war against each other. It’s by dipping into their ever-evolving chemical arsenal that we keep our pharmacies supplied with the antibiotics we use to fight infectious bacteria - and computer biologist Luis Coelho of Queensland University of Technology has turned to genetics and AI to speed up the search for novel compounds.

Research from Elana Hobkirk at Durham University has found that the process of domestication and selective breeding has limited the ability of domestic dogs to use facial expressions to convey emotions as effectively as their wolf ancestors. Whilst we may be easily manipulated by the ‘puppy eyes’ of our pet dogs, they are no longer able to display the same range of emotions that wolves can, who need strong visual communication to maintain their packs.

Who discovered the first black hole? Science writer Marcus Chown tells us about the discovery of Cygnus X-1 discovered by Paul Murdin and Louise Webster in 1971.

And 100 years ago this week, Indian physicist Satyendra Nath Bose posted his revolutionary paper to Albert Einstein, which went on to influence quantum mechanics, low-temperature physics, atomic physics, and the physics of the particles that shape the Universe. Physicist Ajoy Ghatak and presenter Roland Pease discuss the story of the man who had the word ‘boson’ coined to memorialise him in the late 1920s.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

AI is already being used in every branch of science, and will become more and more a feature of future breakthroughs. But with its power to find subtle patterns in massive data sets comes a concern about how we will know when to trust its outcomes, and how to rely on its predictions. Science in Action talks to Alison Noble who just completed a Royal Society report on trust in scientific AI.

With highly pathogenic bird flu infecting around 70 dairy herds across 10 states in the USA, including a herd of alpacas, we get an update from health journalist Helen Branswell of StatNews on the latest science and efforts to get on top of the infection.

Also, from the pioneers of the mRNA vaccines that helped turn around the COVID pandemic, an experimental version that could be rolled out rapidly if the bird flu does cross worryingly into people. University of Pennsylvania’s Scott Hensley described how it works, and how promising it looks.

Science in Action also hears how Europe’s new EarthCARE satellite, equipped to peer deep inside clouds, will tackle one of the biggest unknowns in the science of global warming.

Presenter: Roland Pease Producer: Jonathan Blackwell

Fentanyl is a powerful morphine substitute, but it is also incredibly addictive – millions struggle with weaning themselves off it. And of the 600,000 drug deaths worldwide each year, the World Health Organisation estimates 80% are due to opioids in general, with synthetic opioids like fentanyl being a growing part of the problem. New work with genetically manipulated mice suggests that fentanyl affects two parts of the brain, one associated with the high, but also another that regulates fear. This knowledge could aid in the development of treatments to reduce addiction to the opioid.

Early developers: Long before a developing implants into a mother's uterus, in fact as the fertilised egg divides for the first time into a pair of cells, which line becomes the future baby and which will become the 'life support' system of the placenta has been decided. Embryologist Magdalena Zernicka-Goetz explains why this early unfolding of the genetic programme is important, and why it's taken so long to discover it.

Getting through pregnancy is only the first step in a person’s life. Surviving childhood, particularly for our old stone age ancestors, was the next challenge. And a new study looking at children’s teeth found at ancient archaeological sites gives clues as to why our ancestors fared better than the neanderthals around them during the last ice age.

Supersense: twitching hairs on some caterpillars turn out to be early-warning sensors feeling the electric field of an approaching wasp, giving the potential prey precious moments to hide or escape death. Biophysicist Daniel Robert explains the challenge of seeing the electric world of insect hunters and hunted.

Presenter: Roland Pease Producer: Jonathan Blackwell Production co-ordinator: Jana Bennett-Holesworth

(Image: Fentanyl. Credit: Isaac Lee via Getty Images.)

They were the best northern and southern lights in decades, but why? And what’s next? We hear from astrophysicist Steph Yardley about the solar maximum, geomagnetic storms and atmospheric spectaculars.

Also, the impossible heatwave in the Philippines made possible by global warming – the analysis of a continent-spanning climate extreme by the World Weather Attribution collaboration.

Getting close up to raging tornadoes in order to fill in the big gaps that remain in the science of their development.

And the tale of the lizard’s tail, and how it could lead to safer buildings in the future.

(Photo: The aurora borealis, also known as the 'northern lights’, are seen over The Roaches near Leek, Staffordshire, Britain, May 10, 2024. Credit: Carl Recine/Reuters)

Presenter: Roland Pease Producer: Jonathan Blackwell

Could future blood transfusions be made safer by mixing in a new bacterial enzyme? Every year 118 million blood donations need to be carefully sorted to ensure the correct blood types go to the right patients. Prof Martin Olsson, of Lund University in Sweden, and colleagues in Denmark have published a study that suggests an enzyme made by bacteria in our gut could edit our blood cells to effectively convert type A, B and AB to type O. This would be a step towards a universal blood type that could be given to any patient.

Papua New Guinea’s Naomi Longa is a “Sea Woman of Melanesia”. She works to train local women from the Kimbe Bay region of the Coral Triangle to dive, snorkel, navigate and use AI to monitor the coral reefs there. She is winner of this year’s Whitley Award, and tells us why it is socially and scientifically useful to get locals - specifically females - involved in conservation efforts there.

Data scientist and roboticist Prof Daniele Rus of MIT has been using Machine Learning to decipher structure in a vast swath of Sperm Whale song data from Dominica. They have discovered a set of patterns and rules of context that seem to govern the way sperm whales structure their distinctive sets of clicks. The next step? See if we can decode any semantic content…

Also, 200 years after Beethoven’s 9th symphony premiered, science says its composer couldn’t hold a beat. A cautionary tale of the hubris of genetic data miners, Laura Wesseldijk describes to Roland how she and her collaborators designed the paradoxical study to point out the limitations of finding any sort of “musical genius” genes with contemporary techniques.

Presenter: Roland Pease Producer: Alex Mansfield Production Coordinator: Jana Bennett-Holesworth

(Image: Two Sperm Whales, Caribbean Sea, Dominica. Credit: Reinhard Dirscherl via Getty Images)

As bird flu is found in US farm cats fed on raw cow’s milk, chimpanzees are observed eating infected bat dung instead of vegetables. There is a constant threat of infections crossing from species to us and also from species to other species, particularly because of what we do. That is, after all, what happened to start the pandemic.

We hear about the ongoing struggles of the Chinese virologist who broke his instructions in China in order to share the first COVID genetic data.

And a strange tale of how tobacco growing might provide bat viruses a path into other species.

Presenter: Roland Pease Producer: Alex Mansfield Production co-ordinator: Jana Bennett-Holesworth

Image: Cows on an American cattle farm (Credit: Adam Davis/EPA-EFE/REX/Shutterstock)

Friday, April 13th 2029 – mark it in your calendar. That’s the day an asteroid the size of an aircraft carrier will fly past Earth, closer than some satellites. Don’t worry – it will miss, but it’ll will pass so close to Earth that it will be visible to the naked eye of 2 billion people, particularly in North Africa and Western Europe.

Roland Pease this week attended the Apophis T-5 Years conference at the European Space Research and Technology Centre (ESTEC) in the Netherlands, meeting astronomers scrambling to get missions up to the object to learn what kind of threats such asteroids might pose to us in the future and to discuss the science of planetary defence.

NASA’s OSIRIS-APEX, a follow-on to OSIRIS-REx, will study the physical changes due to the gravitational forces from the Earth as it closely passes us by. But will there be an armada of spacecraft sent to monitor Apophis? The European Space Agency hope to gather support for their own mission, RAMSES.

Presenter: Roland Pease Producer: Jonathan Blackwell

Image Credit: JPL/Caltech

A black hole just discovered in our Milky Way galaxy, weighing 33 times the mass of the Sun, and dating back to near the time of the Big Bang, gives new clues to the origins of this dark astronomical mysteries. And dancing with a Sun-like star in our galactic neighbourhood, it offers a great opportunity for astronomers to take a detailed look in coming years, as astronomer Professor Gerry Gilmore of Cambridge University tells the programme.

Presenter Roland Pease has headed to the lab of Professor Ludovic Orlando in Toulouse, France where they are extracting ancient DNA from horses as part of a project called “Horsepower” - to reveal how our prehistoric ancestors tamed and domesticated these powerful animals (long after cattle and sheep) and in the process helped shape the extraordinary history of the first states of China and Mongolia. And a deep look into the mechanisms of addiction – showing how drugs of abuse, such as cocaine, hijack the neuronal pathways that had evolved to drive our innate needs such as eating and drinking. Roland hears from psychiatrist Eric J. Nestler of the Friedman Brain Institute at Icahn School of Medicine at Mount Sinai in New York, how this could one day improve addiction treatments.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

(Image: An artist's impression shows the orbits of the most massive stellar black hole in our galaxy, dubbed Gaia BH3, and a companion star. Credit: European Southern Observatory via Reuters)

The highly pathogenic strain of bird flu, H5N1, has arrived on the continent. Australian bird specialist Megan Dewar, from the Federation University of Australia, has led a mission aboard the research ship the Australis.

Science in Action remembers physicist Peter Higgs 60 years after his Nobel prize winning theory of the Higgs particle.

The unfolding scandal of manipulated data behind claims of incredible room-temperature superconductivity. Science writer Dan Garisto has seen the details in a Rochester University internal investigation.

And the alga – single-celled seaweed – with superpowers. As well as capturing carbon from CO2 in the atmosphere, like other plants, this one can directly capture nitrogen too, essential for life, but which few organisms can do for themselves. We hear from the marine scientist who has revealed this evolutionary trick.

Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

(Image: KAPPA-FLU team selecting skua carcasses for post-mortem examination. Credit: Ben Wallis)

A powerful earthquake hit Taiwan on Wednesday morning, but thanks to the country’s early warning system and engineering-preparedness, there was little destruction and few deaths. Seismologist Ross Stein, CEO of earthquake consultancy Temblor, Inc., shares his analysis. The highly pathogenic bird flu H5N1 has been detected in cattle in the US and in a cattle handler in Texas. To learn more about this special animal-to-human transmission, Roland speaks to virologist Richard Webby of St. Jude Children’s Research Hospital in Tennessee and Director of the World Health Organization Collaborating Center for Studies on the Ecology of Influenza in Animals. French Space Institute Supaero in Toulouse is collaborating with Japan’s space agency JAXA to send and land a rover on Phobos, one of Mars’ tiny moons. Roland travels to the University of Toulouse to learn more about building this wheeled Rover from Supaero’s Naomi Murdoch.

Transitioning to a clean energy future requires mining materials like rare earth minerals, but how will this impact our environment? Jessi Junker of the ecology charity ReWild explains her research and concerns for great apes as mining for these materials expands in Africa.

Presenter: Roland Pease Producers: Roland Pease, Ella Hubber, Jonathan Blackwell Researcher: Imaan Moin Production Coordinator: Jana Bennett-Holesworth

(Photo: Damaged building caused by the earthquake in Hualien on April 4, 2024. Credit: SAM YEH/AFP via Getty Images)

3000 light years from Earth, a white dwarf star called T Coronae Borealis is on the brink of a “once-in-a-lifetime” explosion. Astrophysicist Bradley Schaefer is enthusiastic about the bright star set to appear in the night sky in the coming months.

Professor Irving Weissman has been researching ways to restore youth using mouse models for decades. He has sewn old and young mice together to join their circulatory systems and has found that giving old mice blood from younger mice reverses some signs of ageing. In his group’s paper, the use of an antibody-based therapy has been shown to restore a declining immune system in ageing mice. Not quite the fountain of youth but potentially a key step in halting many age-related diseases. Roland gets the details from Irving and first-author Dr Jason Ross.

And, in the small town of Cabrières in Southern France, producer Ella Hubber goes on the hunt for some 480-million-year-old fossils with part-time fossil prospectors Eric and Sylvie Monceret. Their latest excavation site is a gold mine of rare, soft-bodied fossils from the period during a time when this part of France was underwater. And at the South Pole.

Presenter: Roland Pease Producer: Ella Hubber

(Photo: Illustration of the northern springtime constellations of Lyra, Hercules, Corona Borealis, and Bootes. Credit: Alan Dyer/Stocktrek Images)

The last great "out of Arica" movement of our ancestors swept out of the northeast of the continent 74,000 years ago. Archaeologist John Kappelman of the University of Texas brings us an update to this complex tale in the form of animal carcasses.

We take a trip to Oxford to meet some of postgraduate researcher Ally Morton-Hayward's archive of preserved brains. Not only is Ally shining a light on these underappreciated brains, she is also using them to unlock a rich treasure-trove of information about our ancestors and how they were preserved.

How do you develop and promote a vaccine against a widespread but neglected parasite? Maria Elena Bottazzi from Baylor College of Medicine is in India promoting their latest development in creating a hookworm vaccine that works against these life-limiting childhood parasites.

And, is the Chandra X-Ray Observatory at risk? In a decision that has shocked astronomers, the functioning telescope is on the chopping block because of NASA budget cuts. We hear from Belinda Wilkes of Bristol University about Chandra’s impressive history and why it should keep going.

Presenter/producer: Roland Pease Researcher: Katie Tomsett Production co-ordinator: Jana Bennett-Holesworth

(Image: Sunset in savannah of Africa. Credit: Anton Petrus via Getty Images)

After a twelve-month set of climate records driven by global warming it is time to take stock of how we’re impacting the planet as a species.

Coral biologist Kate Quigley, of the Minderoo Foundation and James Cook University, dives into the 8th mass bleaching event at the Great Barrier Reef. We explore how deadly heat stress continues to threaten this underwater paradise and induce mass sickness in the corals that call it home. Heading onto land we reunite with Mike Flannigan, Professor of Fire Science at Thompson Rivers University, after a record-breaking Canadian forest fire season in 2023 we ask if conditions are set for a repeat.

And what about the human cost of these climbing temperatures? In the future 800 million outdoor workers in the tropics may be exposed to intolerable heat stress. However, Yuta Masuda, director of science at the Paul G Allen Family Foundation, advises that options for individual action may be limited for workers to protect themselves.

One of the driving forces behind a record year of global warming is the now waning El Niño system. With its counterpart, La Niña, due to pick up in 2024, we ask NOAA oceanographer Mike McPhaden what to expect from this transition and if we are headed for a turbulent hurricane season. Presenter/producer: Roland Pease Researcher: Katie Tomsett Production co-ordinator: Jana Bennett-Holesworth

(Photo: The McDougall Creek wildfire burns in the hills West Kelowna, British Columbia, Canada, on 17 August, 2023. Credit: Darren Hull/ AFP)

Astronomers using the James Webb Space Telescope think they have seen the glow from the first generation of stars after the Big Bang. Newton Kavli Fellow Hannah Übler discusses.

The Anthropocene is meant to mean the latest geological era in which humanity is shaping the rocks and environment of our planet. But an unexpected vote by a commission has declined the idea of making this an official definition. Roland hears from one of its leading proponents, geologist Jan Zalasiewicz, about what happened and why it matters.

And, new research indicates that bumblebees can show each other how to solve puzzles too complex for them to learn on their own. Professor Lars Chittka put these clever insects to the test and found that they could learn through social interaction. How exactly did the experiment work, and what does this mean for our understanding of social insects? Reporter Hannah Fisher visits the bee lab at Queen Mary University in London.

Plus, the subterranean South American snake, or rather snake-like amphibian, that feeds its hatchlings milk from specially evolved glands. Brazilian biologist Carlos Jared explains more about this species’ nurturing behaviour.

Presenter: Roland Pease Producer: Roland Pease Production Coordinator: Jana Bennett-Holesworth

(Photo: A portion of the GOODS-North field of galaxies, highlighting the galaxy GN-z11, which is seen at a time just 430 million years after the Big Bang. Credit: Nasa/ESA/CSA/B. Robertson (UC Santa Cruz), B. Johnson (CfA), S. Tacchella (Cambridge), M. Rieke (University of Arizona), D. Eisenstein (CfA))

The All of Us Research Program is undergoing the herculean task of gathering genomic data from over one million people living in the United States, from widely different backgrounds, in the hopes of accelerating health care research. However, within the scientific community many, including Ewan Birney, deputy director general of the European Molecular Biology Laboratory, are concerned that the way some of this data has been framed in a recent paper could reinforce racist beliefs. We also learn about the program and hear a response to the criticism from Josh Denny, the CEO of the All of Us Research Program.

Over the past two years, a deadly version of bird flu, H5N1, has been spreading around the globe, killing hundreds of thousands of birds and mammals in the process. Isolated from the rest of the world, animals in Antarctica have been safe from the virus so far. But, virologist Antonio Alcamí, who is located on the continents Spanish base, confirms that bird flu has reached them, infecting Antarctic skua seabirds.

And, on a less serious note, can the smell of a female cause premature death? Maybe in mice. Researcher Mike Garratt goes over the intriguing results in his new mouse study.

Presenter: Roland Pease Producer: Ella Hubber Production co-ordinator: Jana Bennett-Holesworth

(Image: Colorful diverse crowd in modern collage. Credit: Dedraw Studio via Getty Images)

A monumental Covid vaccine safety study of 99 million vaccinated people confirms just how rare adverse effects are and combats growing vaccine misinformation. Co-director of the Global Vaccine Data Helen Network goes through the results of this massive study.

This week, Science in Action is bringing you not one, but two extraordinary astronomical discoveries. First, Webb Fellow Olivia Jones on the star hidden in the heart of only supernova visible from Earth. Second, astrophysicist Samuel Lai on what is possibly the brightest object in our universe – a whopping 500tn times brighter than our sun – a star eating quasar.

And Roland chats with biologist Charlotte Houldcroft who was one of the first to blow the whistle on an absurd, AI generated image which somehow made it through the peer review process.

Presenter: Roland Pease Producer: Ella Hubber Production Coordinator: Jana Bennett-Holesworth

(Image: A health worker injects a man with a shot of the Inavac vaccine for Covid-19. Credit: BAY ISMOYO/AFP via Getty Images)

High-profile climate scientist Michael Mann has been embroiled in a 12-year battle against conservative commentators who claimed his data was fraudulent. Last week, he was awarded $1m in a defamation lawsuit. Michael joins Science in Action to discuss the case and the impact it may have.

Also, this week, Karyn Rode from the US Geological Survey has been using cameras on collars to track polar bear movement and diet. She tells Roland how the data reveals the devastating effect of sea ice loss on the bears.

Widescale blackouts in Africa, known as loadshedding, are getting worse. Chemist and winner of The Royal Society Rising Star Africa Prize 2023, Wade Peterson, has an innovative chemical solution to the problem.

And using a forest to detect the most violent astrophysical sources in our universe? Physicist Steven Prohira thinks it’s possible.

Presenter: Roland Pease Producer: Ella Hubber Production Coordinator: Jana Bennett-Holesworth

(Image: Dr. Michael E. Mann is seen outside of the H. Carl Moultrie Courthouse on February 5, 2024 in Washington, DC. Credit: Pete Kiehart for The Washington Post via Getty Images)

Should CERN be spending $17 billion on a new atom smasher whilst we face, climate change, the most pressing crisis of our time? Materials-turned environmental scientist Mark Miodownik and CERN physicist Kate Shaw debate the issue.

One of the issues Mark argues more people should be tackling are the climate change driven forest fires which recently ravaged Chile and killed more than 100 people. Chilean climate scientist Raul Cordero discusses the factors which led to the devastating fires.

And Nasa physicist and oceanographer Susanne Craig explains their freshly launched satellite PACE, which hopes to get a better picture of our changing oceans and use this information to tackle climate change. A quest Nasa manages to achieve whilst also trying to answer the big questions about our universe.

Presenter: Roland Pease Producer: Ella Hubber Production co-ordinator: Jana Bennett-Holesworth

(Photo: Firefighters work at the Botanical Garden after a forest fire in Viña del Mar, Chile, 4 February, 2024. Credit: Javier Torres/AFP)

Starting upbeat this week, engineer Teddy Tzanetos, team lead of NASA’s Ingenuity mission, talks on the Mars-based helicopter which defied all expectations. Our big story this week is on the scientific papers and research databases which contain the DNA profile of thousands of people from persecuted ethnic minorities in China. This data is often collected in association with security forces. Computational biologist and campaigner Yves Moreau now leads the call for scrutiny and the retraction of these papers and databases, which lack evidence of free and informed consent. We often cover the ever-growing threat of bird flu to mammalian populations on Science in Action. But how does the virus make the successful leap from bird to mammal cells? Virologist Wendy Barclay discusses the potential tricks the virus uses to adapt and grow.

And, finally, zoologist Sam Fabian has been trying to answer the question everyone thinks they already know: why are moths attracted to artificial light?

Presenter: Roland Pease Producer: Ella Hubber Production Coordinator: Jana Bennett-Holesworth

(Image: Protest in Urumqi in China's far west Xinjiang province on July 7, 2009. Credit: PETER PARKS/AFP via Getty Images)

Molecular biologist Prof Jason Chin tells us about his research into accelerated evolution and how it could help create new substances to be used in medicine, chemistry and more.

In South America, palaeogeneticist Dr Verena Schuenemann has been extracting genetic material from human remains to find out more about treponemal diseases, which include syphilis, yaws and bejel.

And moving across the Atlantic to the Mediterranean, volcanologist Professor Timothy Druitt has discovered new evidence of a massive volcano that erupted beneath the sea near Santorini around 500,000 years ago.

Staying in the Mediterranean, we speak to Professor Rachel Flecker, co-chief scientist on Expedition 401 of the International Ocean Discovery Program. She and her team are drilling down into the seabed to establish how the Gibraltar Strait has altered over time. As well as influencing the Mediterranean's salinity, this changing movement of water has impacted the entire planet's oceans and climate.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Production co-ordinator: Jana Bennett-Holesworth

(Image Credit: Thomas Ronge)

African swine fever has now reached Southeast Asia.This part of the world has high diversity in wild pigs, some of which are endemic to their native islands. In Borneo, pigs are a hugely important food source for indigenous populations, and are a vital prey species for many big cats. In some regions, the pig populations have now dropped by 90 to 100 per cent due to swine fever. Conservationist Dr Erik Meijaard explains what this could mean for Borneo.

Sticking with diseases, the World Mosquito Program breeds mosquitoes infected with Wolbachia. Why? Because mosquitoes infected with this bacteria are unable to become carriers of dengue, Zika and other mosquito-borne diseases. Dr Scott O'Neill of the World Mosquito Program talks about their latest research and the massive mosquito factory they're building in Brazil this year.

Finally this week, Dr Nitzan Gonen discusses her new study, where mouse testes organoids have been grown in the lab. She tells us about the potential applications for this research.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Production co-ordinator: Jana Bennett-Holesworth

(Photo: Bornean bearded pig. Credit: Sylvain Cordier/Getty Images)

The James Webb Space Telescope has revealed the clearest ever view of the stunning Cassiopeia A supernova, complete with a weird feature called 'the green monster'. Professor Dan Milisavljevic, an astronomer at Purdue University, tells us all about his research into this space-based beauty.

Professor Tamara Davis from the University of Queensland has been turning her eye to far more distant supernovas, and explains how they have given us new insight into the Universe's expansion.

Moving on to human history, William Barrie from the University of Cambridge tells us about a new study that explores the reason for high levels of multiple sclerosis in northern Europe.

And going further back in time, researcher Ethan Mooney has studied a sample of fossilised skin, which may be the oldest ever discovered.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth

(Photo: Cassiopeia A Supernova. Credit: Nasa, ESA, CSA, STScI, Danny Milisavljevic, Purdue University, Ilse De Looze, UGent, Tea Temim, Princeton University)

In this episode of Science in Action, we find out that tuberculosis (TB) is the leading cause of death in South Africa.

After visiting a clinic dedicated to the diagnosis and treatment of TB, Roland Pease meets researcher Professor Grant Theron at Stellenbosch University, who explains why the disease is still so prevalent.

Next we hear from Professor Novel Chegou and his student Candice Snyders, also based at Stellenbosch University. They are researching biomarkers to diagnose tuberculosis and have already successfully developed a rapid finger-prick test to identify TB.

Roland then chats to vaccine researcher Professor Thomas Scriba at the University of Cape Town, who reveals more about the current landscape of TB vaccination.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth

(Photo: Frontline healthcare workers wear a protective mask and tb mask to prevent the spread of airborne disease. Credit: stockstudioX/Getty Images)

In this special episode of Science in Action, Roland Pease travels to South Africa to gain a deeper understanding of human origins.

Along the way, he speaks to ichnologist Charles Helm and national parks ecologist Mike Fabricius, who take him to a special – and extremely windy – location, where early human footprints are permanently preserved in the rock. At the University of Cape Town, Roland speaks to Rieneke Weij and Georgina Luti. They are studying the geochemistry of rocks that existed in caves alongside our ancient relatives.

Across the city, in the Iziko South African Museum, Wendy Black and Amy Sephton discuss the ways in which we think about our deep past and how we can decolonise the human story.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth (Image: Human fossilized footprint in hardened mud or clay. Credit: Waltkopp/Getty Images)

This week, the Reykjanes volcano in Iceland has erupted, following weeks of seismic activity. Edward Wayne Marshall, from the University of Iceland, brings us the latest science about the volcano.

Also this week, the UK's 40-year-old JET fusion facility has been switched off. Roland Pease went along to watch.

Fusion facilities are trying to create clean energy by replicating the processes in the Sun. And the Sun itself is currently approaching solar maximum, which means we may get to enjoy more spectacular auroras but could also experience widespread radio blackouts. Solar physicist Dibyendu Nandi, from the Centre of Excellence in Space Sciences in Kolkata, tells us more.

And in the outer reaches of our Solar System, the iconic Voyager 1 craft has started sending back nonsense data. William Kurth, who has worked on Voyager since its launch in 1977, reveals his personal and scientific connection to the mission.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: Volcano Erupts On Iceland's Reykjanes Peninsula. Credit: Micah Garen/Getty Images)

An international team of researchers led by the University of Cambridge’s Prof Stephen O’Rahilly have discovered that sensitivity to the hormone GDF15 may cause severe morning sickness during pregnancy. Dr Marlena Fejzo, who took part in the study, tells us more.

Back in September, the OSIRIS-REx craft dropped a sample from the asteroid Bennu into the Utah desert. Now, scientists around the world have started studying the dust fragments in earnest. We join Dr Ashley King from the Natural History Museum in London and beamline scientist Dr Sharif Ahmed as they embark on their research.

Professor Scott Fendorf, from the University of Stanford, reveals that wildfire smoke contains heavy metals, which may be why it’s so damaging to our health.

Dr Junjie Yao from Duke University has worked on a new 'sono-ink'. This ink can be used to 3D print structures within the body, which can be used to mend tissues, bones and organs.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Photo: Young pregnant woman, 35 years old, feeling sick on a toilet. Credit: Getty Images)

The burning of fossil fuels releases the greenhouse gas CO2. Many countries at COP28 have expressed an interest in using carbon capture technology to permanently capture and store this CO2. Climate and energy expert Dr Richard Black tells us more about this technology and how helpful it is in the fight against climate change.

Sticking with COP28, Dr Manjana Milkoreit, from the University of Oslo, contributed to this week’s Global Tipping Points report, which revealed the Earth could be racing toward a set of critical thresholds that will put the Earth into a new state.

Dr Joyce Kimutai is also at COP28. Originally from Kenya, she’s the lead author of a new paper from World Weather Attribution. The paper found that climate change has made deadly rainfall in East Africa up to two times more intense.

And finally, this week Professor Dany Azar published a paper in Current Biology that not only identified the oldest fossilised mosquito, but also found that it was a male with blood-sucking mouthparts – a trait only seen in female mosquitoes today.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: TBC. Credit: TBC / Getty Images)

This week, the RRS Sir David Attenborough arrived in Antarctica to start its first full season of science in the polar region. Dr Nadine Johnston reveals more about the mission and the research they’ll be carrying out.

Next up, medical geneticist Professor Shahida Moosa and her student Jessica Jane Cormick are working to help diagnose and treat rare diseases. They explain why better genetic databases for Africans are urgently needed.

We also hear from Simon Evans of the Carbon Brief, who has just completed an analysis that found the responsibility for climate change dramatically shifts once historical rule and colonialism are taken into account.

Finally, a new study has revealed that emissions from coal-fired power plants have led to the deaths of nearly half a million Americans in the last 20 years. Professor Cory Zigler, from the University of Texas at Austin, tells us more.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth Sounds provided by: Nadine Johnston and Katherine Turner from BAS and the University of Southampton

(Image: A general view of the RRS David Attenborough vessel on October 28, 2021 in Greenwich, England. Credit: Photo by Leon Neal/Getty Images)

This month, Brazil has seen some of its highest recorded temperatures. The country’s Pantanal wetlands, the largest tropical wetlands in the world, have been scorched by wildfires. The region is home to vibrant wildlife, including jaguars, anacondas and various birds.

Professor Letícia Couto Garcia, leader of the Intervention Ecology Lab at Mato Grosso Federal University in the South, Brazil, talks about some of the challenges she’s experienced.

Staying with extreme temperatures, Dr Robert Rohde of the independent non-profit, Berkeley Earth, reveals what the recently recorded excess of 2°C means.

This week, we learned that an extremely energetic particle had been detected. Dr Toshihiro Fujii of Osaka Municipal University tells us how he first made the discovery after trawling through some data. We then hear from Dr Yvette Cendes, an astronomer who specialises in high-energy physics, to find out more about the origins of this particle.

Finally, Science in Action visits the South African Astronomical Observatory, to learn about the projects that could bring more diverse voices to our understanding of the night sky.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth (Image: Firefighters tackle forest fires in the Pantanal wetland near Porto Jofre, Mato Grosso State, Brazil, on November 13, 2023. Credit: ROGERIO FLORENTINO/AFP via Getty Images)

Increased tremors have been felt in Iceland, and concerns about an impending eruption have led to the evacuation of the town of Grindavik. Geophysicist Dr Freysteinn Sigmundsson reveals more about the events and whether this area of Iceland may be entering a new period of volcanic activity that could span centuries.

Also, Google DeepMind’s new GraphCast system could revolutionise weather forecasting. Rémi Lam from Google DeepMind and Dr Matthew Chantry from the European Centre for Medium-Range Weather Forecasts explain how it works.

Beyond warming our planet, climate change can have wide-ranging, unexpected impacts on people and the environment. Dr Christopher Trisos from the University of Cape Town has the lowdown.

Finally, recreating ancient seawater in the laboratory has given Dr Rosalie Tostevin, a geochemist from the University of Cape Town, additional information about the metals used by early microbes.

Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: Emergency services worker walking near a crack cutting across the main road in Grindavik, southwestern Iceland following earthquakes. Credit: KJARTAN TORBJOERNSSON/AFP via Getty Images)

This week we're out in the wild and noisy spaces in and around Cape Town, South Africa.

Ichnologist Charles Helm takes Roland on a bumpy ride in Walker Bay Nature Reserve to hunt for fossilised animal tracks, with a few brilliant surprises.

Producer Ella Hubber visits the SANCCOB seabird rehabilitation centre to speak to researcher Katta Ludynia about what challenges the African penguin faces. We also hear about the ever-present threat of bird flu from SANCCOB vet David Roberts.

And, in the beauty of Kirstenbosch Botanical Gardens, Tess Gridley and her team from the African Bioacoustics Community are collecting the sounds of South Africa's diverse bird populations for the public and future conservation efforts.

Presenter: Roland Pease Producer: Ella Hubber Content Producer: Rema Mukena Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth (Image: Roland records Ichnologist Charles Helm at Walker Bay Nature Reserve. Credit: Ella Hubber)

Category 5 hurricane Otis, which devastated Acapulco, was supercharged by global warming; hurricane expert Kerry Emanual tells Science in Action.

Also, Brazilian ecologist Erika Berenguer has witnessed the destruction caused by the prolonged drought in Amazonia, where the rivers are drying up and the forest is burning.

And, climate scientists now say there is less time than previously thought to avoid further dangerous warming. Two climate scientists, Chris Smith and Norman Loeb, break the bad news - that the climate is more sensitive to greenhouse gases than forecasts have used.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth

(Photo: A woman sits amongst the damage after Hurricane Otis. Credit: Silvana Flores/Getty Images)

Fear that the highly infectious variant of avian influenza, H5N1, would reach the Antarctic region and put isolated bird populations at risk has finally come to fruition as the first birds on Bird Island in the Atlantic Ocean have come down with the devastating illness. Science manager of the island, Ashley Bennison, explains the situation. Then, from one extreme climate to another - mummified mice have been found on the summit of volcanoes across the Andes, raising questions as to the capacity for vertebrates to survive in extreme conditions.

Kevin Langergraber has been studying the Ngogo chimpanzee community in Uganda for over 20 years. Now, Kevin and colleague Brian Wood tell us how this group are experiencing something thought to be unique amongst humans (and some whales): menopause.

And, how geophysicist Amir Kahn used seismic activity on Mars to understand what the core of our neighbouring planet is made of.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: Wandering Albatross, Diomeda exulans, displaying at Cape Alexandra above Bird Sound and Bird Island in background South Georgia. Credit: Education Images/Universal Images Group via Getty Images)

Accelerating seismic tremors are raising concerns for the thousands of people living atop a volcanic hot spot close to Naples, Italy. Volcanologist Alessandro Pino has been keeping a watchful eye on the developing situation.

We stay in Naples where, almost 2000 years ago, the eruption of Mount Vesuvius buried Pompeii, including thousands of scrolls turned to charcoal by the immense heat. This hasn’t stopped people from trying to read the scrolls, destroying hundreds in the process. Now, computer scientist Brent Seales has deployed AI and papyrologists worldwide to decipher the burnt text.

And from ancient scrolls to rainforest soundscapes, ecologist Zuzana Buřivalová has also been using AI to untangle the vast array of life heard in forests, old and new, as a tool to measure biodiversity.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: A view of the fumaroles Pisciarelli in Agnano quarter of the Campi Flegrei, a volcano near Naples. Credit: Salvatore Laporta/KONTROLAB/LightRocket/Getty Images)

Lying atop a network of fault lines, where the Indian and Eurasian tectonic plates meet, Afghanistan is prone to earthquakes. However, the Herat area has not seen an event for almost 1000 years. As such, it was the least likely area to experience the series of devastating earthquakes and aftershocks which are reported to have killed thousands this week. Afghani seismologist Zekaria Shnizai discusses the factors which led to the disaster.

After a couple of delays, NASA’s Psyche mission is due to launch this Friday. It will map Psyche, a metal-rich asteroid orbiting the Sun between Mars and Jupiter. Project leader Lindy Elkins-Tanton's excitement for the project is infectious.

And can deep learning help us predict the next pandemic? Computational Biologist Debora Marks’ new tool, Evescape, can predict the most likely mutations a virus will gain under pressure. This could be a game changer.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: An Afghan man sits amid the rubble after a massive 6.3 magnitude earthquake strikes the city of Herat. Credit: Esmatullah Habibian / Getty Images)

The 2023 Nobel Prize in Physiology or Medicine was awarded to Katalin Karikó and Drew Weismann for their contributions to developing the fundamentals that led to life saving mRNA vaccines. Although funding and support were not always assured on their road to the Nobel, Katalin Karikó tells Roland she used these setbacks to drive her towards success.

On the other side of the coin, allegations of scientific misconduct over bold room temperature superconductivity claims. Earlier this year, eleven authors submitted a paper to Nature. Now, eight of them are calling for a retraction. Science journalist Dan Garisto covers the story.

Also this week, NASA Ames researcher Jacob Kegerreis details how Saturn got its rings. Hint: It’s a smashing story.

And, what is the most fear inducing sound in the world? Lions roaring? Gunshots? According to mammals in South Africa it is the human voice. Fear-ecologist Liana Zanette explains.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: Katalin Karikó. Credit: Mark Makela / Getty Images)

What did a 465-million-year-old trilobite eat for dinner? And how can we possibly know? Archaeologist Per Ahlberg has used x-ray to peer into the guts of one ancient scuttling creature and worked out what it what was munching on in its final moments.

From life in ancient earth rocks to potential life in space rocks, mineralogist and astrobiologist Bob Hazen has been training AI to spot signatures of life on Earth. He now hopes to use this tool on space samples.

We also ask experimental particle physicist Jeffrey Hangst how antimatter, the last mystery of the universe, responds to gravity - was Einstein's theory of general relativity right?

And the antiviral Covid medication, Molnupiravir, may be causing the virus to mutate. Theo Sanderson discusses how he figured this out and how concerned we should be.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth

(Image: Fig. 1: Bohemolichas incola (Barrande, 1872). Credit: Kraft et al)

Storm Daniel devastated the city of Derna in Libya after heavy rainfall broke a dam, causing extreme flooding downstream. The World Weather Attribution (WWA) reports that severe flooding in Libya and across the Mediterranean has been made more likely and more intense due to human induced climate change. WWA scientist Friederike Otto gets into the report.

Back in 2020, NASA’s OSIRIS-REx scooped up rock and dust samples from asteroid Bennu and on Sunday September 24th, 2023 the sample capsule will finally be released 100,000 kilometres above Earth, delivering it to the Great Salk Lake Desert. OSIRIS REx engineer Anjani Polit tells us about the nail-biting return.

Also this week, Dr Peter Hotez warns us about the dangerous and rapid rise of anti-science sentiment in the United States. It’s all in his new book "The Deadly Rise of Anti-Science".

And the remnants of what is thought to be the oldest wooden structure have been found in Zambia. Professor of Archaeology Lawrence Barham talks about the simple structure made by our ancestors almost 500,000 years ago.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: Building collapsed and surrounded by rubble following floods in Derna. Credit: RICARDO GARCIA VILANOVA / Getty Images)

Earlier this week the deadly Mediterranean cyclone, Storm Daniel, swept through the small city of Derna in Libya, collapsing a 50-year-old dam in its wake, and triggering devastating floods which have killed over 5000 people. We speak to atmospheric scientist, Stavros Dafis, about the cyclone’s characteristics and to civil and structural engineer, Lis Bowman, about the dam collapse. Unsurprisingly, it all comes back to climate change.

Far, far from Earth, the James Webb Space Telescope has set its site on the atmosphere of exoplanet K2-18b where the presence of methane and carbon dioxide offer the tantalising possibility of an extraterrestrial Ocean. Astrophysicist Nikku Madhusudhan discusses his exciting results.

And an even less expected presence in space: the ancient remains of our ancestors. Archaeologist Lee Berger has come under fire after sending precious bone samples on a Virgin Galactic space flight. South African archaeologist, Robyn Pickering, expresses the frustration that is on everyone’s mind.

Also expressing their anger, two young climate protesters recently stormed the stage during an orchestral performance at a Swiss music festival. But, to everyone’s surprise, conductor Vladimir Jurowski allowed them to speak to his audience. We hear from the Renovate Switzerland protestors, Anthony and Selina, on their unlikely experience.

Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

(Image: Collapsing buildings and flooded land in the aftermath of the Derna floods. Credit: Anadolu Agency / Getty Images)

In September 2012 Arctic sea ice melted to its minimum ever recorded and the German research ice breaker, Polarstern, ventured deep into the region North of Russia to record findings. It’s now retracing its steps, over a decade later, to observe how things have progressed. Autun Purser and Antje Boethius describe the journey and the importance of documenting developments in the face of climate change.

Some 75 million individuals are believed to live with Long Covid and, in order to treat the plethora of symptoms presented by patients, researchers continue to search for the root source of the condition in the hope of better prescribing broad therapeutics. Akiko Iwasaki, Professor of Immunobiology at Yale University, updates Roland on the working hypotheses.

And one year on from the Hunga Tonga eruption, where a shockwave circled the globe four times, researchers have been able to calculate the speed of the currents in the southern Pacific Ocean. BBC correspondent Jon Amos caught up with Michael Clare to hear how other South Pacific Islands can learn from the most explosive volcanic eruption in 100 years.

Presenter: Roland Pease Producer: Harrison Lewis

Global sea levels are rising more than 3mm per year under current climate conditions. At this rate we are due to hit an alarming 7mm rise per year by the end of the century. If this is not slowed, it could lead to the drowning of essential coastal ecosystems like mangroves and lagoons, professor of environmental science Neil Saintilan tells Science in Action.

The seas are also heating up. We’ve covered the devastating effect of marine heatwaves on vibrant sea life like coral reefs before. But what about the less glamourous bottom-dwelling fish? Ecologist Alexa Fredston has found that they may be more robust than we think.

Also this week, bird virus expert Michelle Wille tells us about the imminent threat of bird flu spreading from South America to Antarctica where hundreds of thousands of sea birds are at risk.

And from one south pole to another, we have an update on how India’s mission on the lunar south pole is going with Lunar and Planetary Institute scientist David Kring.

Image Credit: Marie Hickman

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings

Advances in brain-computer interfaces have allowed patients with paralysis to communicate faster, more accurately and more expressively with direct brain to speech translation. Co-author of an exciting new paper in the field, bioengineer Alex Silva, tells Science in Action about his team’s work with patient Ann.

The world has been following the Indian and Russian race to land on the lunar south pole. Producer Ella Hubber gives a timeline of the events leading up to that historic landing.

Also this week, a new prediction model allows us to better prepare for future extreme weather events. But is this worst-case scenario model scaremongering? Roland talks to author Erich Fischer about the projections. And virologist Connor Bamford talks detecting bird flu in wastewater for betting monitoring.

Image Credit: Noah Berger

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings

Hawaii is still reeling from the devastating fires that consumed Lahaina on the island of Maui last week. Professor of Meteorology from the University of Hawaii, Kevin Hamiliton, joins Science in Action to discuss the factors that make these events more likely across the Hawaiian Islands. Amongst these is climate change.

Also this week we discuss the concerning reports of a sudden spike in methane levels in the Arctic with Xin Lan of the US National Ocean and Atmospheric Administration.

A few weeks ago, we devoted a whole programme to the exciting research on human embryo models made from stem cells. Whilst representing an incredible step for medical research, these raise serious ethical questions. A team of biologists and embryologists have put together a proposal on how to move forward with this ethical quandary, Embryologist Nicolas Rivron tells us more.

And we address the incredible claim of the room temperature super conductor, LK-99, with sceptical materials scientist Michael Fuhrer.

Photo: The Maui town of Lahaina after being destroyed by wildfires Credit: Getty Images

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings

ProMED is one of the most useful scientific tools you’ve never heard of. It’s a global surveillance system of infectious disease outbreaks which is available, for free, to researchers and the public alike. But ISID, the society which runs the platform, claim they have run out of money to support ProMED and will be switching to a subscription service, against the wishes of both users and staff. ProMED editor Marjorie Pollak tells Science in Action about the vital service ProMED has played in pandemic monitoring – including the very first COVID outbreaks - and ISID boss Linda MacKinnon considers what’s next for the platform.

From wildfires in Europe to droughts in Africa, we have covered every kind of environmental disaster across most of the globe in the space of the past few weeks. To complete the distressing bucket list of climate extremes, we’re talking to sea ice expert Caroline Holmes on the concerning forecast for Antarctica.

Despite these terrestrial challenges, NASA is still trying to defend Earth against nearby objects which might hit us from space. The Double Asteroid Redirection Test (DART) was launched at the asteroid Dimorphos back in in November 2021 and, a few weeks ago, the Hubble space telescope observed a swarm of boulders shed by Dimorphos post-impact. Some UK newspapers are concerned about their trajectory, but astronomer Dave Jewitt is here to calm us all down.

Photo: Disinfection Work At Wuhan Huanan Wholesale Seafood Market Credit: China News Service

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings

Science in Action returns to H5N1, the fast spreading strain of bird flu which has caused devastation in the sky, sea, and land over the last few months, with no end in sight.

Roland visits Skomer Island and the coast of Wales where sea bird colonies are threatened and hundreds of guillemots have washed ashore dead, struck down by bird flu.

We also hear of outbreaks on Finnish fur farms where controversial plans are in progress for culls of wild birds, of mysterious infections of domestic cats in Poland, and bird flu causing brain swelling in grey seals.

Plus, we get an update on efforts to vaccinate condors in California against the disease.

Photo: Dead Guillemot Credit: BBC

Presenter: Roland Pease Producer: Ella Hubber

A large system of ocean currents known as the Atlantic meridional overturning circulation (AMOC) has been making headlines this week as a new paper predicts its imminent collapse. This could have devastating consequences for the climate. But not all climate scientist and oceanographers are convinced by the results. Stefan Rahmstorf and Eleanor Frajka-Williams debate the contentious paper.

In more positive news, huge steps have been made in the field of gene therapy. Stefano Rivella and Hamideh Parhiz tell us about their incredible mRNA delivery technology which could take much of the cost and risk out of treating debilitating disorders

And as wildfires continue to blaze around the world, reporter Melanie Brown discovers how experts study the physics of these blazes from the Missoula Fire Sciences Laboratory.

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings

For the third year running, Iceland’s Reykjanes peninsula is experiencing another spectacular volcanic eruption. Volcanologist Evgenia Ilyinskaya has been out in Iceland witnessing the sight and getting samples of the noxious fumes.

Across the rest of the Northern Hemisphere heat domes persist, bringing extreme weather ranging from wildfires to tornadoes. We keep on seeing that this year “is the warmest in 120,000 years”. But what does that mean? Two paleoclimatologists, Bette Otto-Bliesner and Jessica Tierney tell us more.

And we’re going deep. Deep into the brain that is, with a newly-developed probe which is finer than a baby’s hair. Dr Anqi Zhang of Stanford University explains her delicate technology.

Finally, new research suggests that SARS-CoV-2 could have arisen in the wild no more than four years ago, a mishmash of other viral genomes. Bioinformatician Jonathan Pekar discusses his new paper.

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings

(Photo: Dr. Evgenia Ilyinskaya Credit: @EIlyinskaya)

As extreme heat returns to much of the world we hear the impact of last year’s heatwaves in Europe, where 62,000 people are estimated to have died. Joan Ballester, Associate Research Professor at Barcelona Institute for Global Health, discusses the figures from his latest paper and his concerns for the future.

This week the European Court of Human Rights ruled in favour of middle-distance runner and Olympic champion Caster Semenya in a case related to testosterone levels in female athletes. Marnie Chesterton speaks to developmental biologist Dr Emma Hilton about what causes differences in sexual development and the impact they can have.

Also, Kew Gardens is going digital. Millions of specimens are being made available to the world for the first time in an enormous digitisation project. Ella Hubber goes behind the scenes at Kew to see some of the precious specimens.

Finally, the Indonesian government has banned a group of foreign scientists from conducting conservation research. Bill Laurance, Research Professor at James Cook University, talks to Science in Action about keeping politics out of conservation science.

Image credit: Getty Images

Presenter: Roland Pease Producer: Ella Hubber

Record-breaking global temperatures are accelerating Greenland ice melt at an alarming rate. Professor of glaciology Alun Hubbard has witnessed the melt first hand. He tells us how the ice sheet is being destabilised and what this could mean on a human level.

Also, how safe are Japanese plans to dispose of nuclear waste from the Fukushima accident? We get reassurance from molecular pathology expert, Professor Gerry Thomas.

And last week was a big one for cosmology news. We catch up on science behind the gravitational hum that permeates the Universe with astrophysicist with Dr Chiara Mingarelli. And we hear about the traces of ghostly neutrinos within our Galaxy from the principal investigator of the world’s largest neutrino detector, Professor Francis Halzen.

Presenter: Roland Pease Producer: Ella Hubber

(Photo: Meltwater forming on top of the Russell Glacier, Greenland)

We have entered a “permacrisis”, an extended period of instability and insecurity, fuelled not only by natural disasters but pandemics, climate change and war.

This week, Science in Action is at the Royal Society as they host the All European Academies assembly on the importance of research in crises. Roland speaks to international experts on how research contributes to responding to and preparing for the multiple and entangled crises of our time.

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings Production co-ordinator: Jonathan Harris

(Photo: A man wearing a protective face mask walks past an illustration of a virus in Oldham, 3 August 2020 Credits: Phil Noble/Reuters)

Over the last week, news of “synthetic human embryos” has made headlines around the world. Science in Action is getting to the bottom of the sensational story.

We talk to two of the researchers who have made the embryo models from stem cells in their labs; Professor Magdalena Zernicka-Goetz from the University of Cambridge and California Institute of Technology, and Professor Jacob Hanna from the Weizmann Institute of Science in Israel. They tell us how they made the embryo models, what their aims are, and their own ethical considerations.

The scientific community is excited, but not surprised, by the breaking research. We hear how Dr Andreia Bernardo, group leader at Imperial College London, could use these structures in her future research.

Finally, Director of the Reproductive Sociology Research Group at Cambridge University, Professor Sarah Franklin, and Professor of Law at Stanford University, Hank Greely, tackle the legal and ethical constraints on this kind of work, and why it is important for understanding the health of mothers and babies.

Photo Credit: Magdalena Zernicka-Goetz Lab

Presenter: Roland Pease Producer: Ella Hubber

As Pacific Ocean temperatures rise, a major El Niño is looming. Experts from the European Centre for Medium range Weather Forecasting, Magdalena Balmaseda and Tim Stockdale, join us to discuss how it is heating up the world and if it could herald in a new period of climate uncertainty.

Last month, Roland stayed up all night to watch the spectacular explosion of supernova 2023ixf. Now, Dr Charlie Kilpatrick, a postdoctoral fellow at Northwestern University, has identified the star that blew up 21 million lightyears away. A similar star in our galaxy, the exceptionally bright Betelgeuse, has been acting strangely. Dr Andrea Dupree, a senior astrophysicist at the Center for Astrophysics, Harvard and Smithsonian, has been trying to figure out what is going on. Is this iconic star about to pop?

And from ageing stars to ageing flies, researchers have published a cell-by-cell map of fruit flies throughout the life of the short lived creatures, showing how they change. Steve Quake, professor of bioengineering and professor of applied physics at Stanford University, tells us what this means for us.

Presenter: Roland Pease Producer: Ella Hubber

(Image: Illustration of the world map showing areas of rising temperatures. Credit: ClimateReanalyzer.org)

The origin of all complex life has been traced back 1.6 billion years as new molecular fossil records have discovered the fatty stains that our ancient single celled ancestors have left behind. Jochen Brocks, Professor of Geobiology at Australian National University, discusses the significance of these unique biological signatures.

One billion years later, to a mere 462 million years ago, life on Earth was experiencing a boom of new species but we have very few fossil records to understand this era. Now, palaeontologists Dr Joe Botting and Dr Lucy Muir have found the most abundant deposit of soft bodied fossils from this time in a tiny Welsh quarry.

Next, to the relatively recent past, 350,000 years ago, where remains found in a South African cave suggest that an extinct species of human, Homo Naledi, buried their dead. But Mike Petraglia, Professor of Human Evolution and Prehistory at the Max Planck Institute, doubts these claims.

And in the modern day, the fungi which have colonised our soil for millions of years are still helping us clean up the atmosphere. Professor of Plant-Soil Processes at the University of Sheffield, Katie Field, tells us about the astounding amount of carbon captured by the fungus beneath our feet.

Presenter: Roland Pease Producer: Ella Hubber

(Image: Artist’s imagination of an assemblage of primordial eukaryotic organisms of the ‘Protosterol Biota’ inhabiting a bacterial mat on the ocean floor. Credit: Orchestrated in MidJourney by TA 2023)

The California Condor has been brought back from the brink of extinction by dedicated conservation efforts over the past 30 years. Now, this critically endangered species is the latest victim of the H5N1 bird flu which is racing round the world. California Condor co-ordinator Ashleigh Blackford and wildlife veterinarian Dr Samantha Gibbs from the US Fish and Wildlife Service discuss their last-ditch efforts to vaccinate the birds against H5N1.

Huge 40,000 km plumes of water ice have been imaged erupting from Saturn’s moon Enceladus. Dr Sara Faggi, a postdoctoral Researcher in the Solar System Division at Nasa Goddard Space Flight Center, dives into this incredible new observation from the James Webb Space Telescope.

Dr Pierre Galand from France’s Observatoire Océanologique de Banyuls has been part of a two-and-a-half-year expedition to sample the microorganisms in coral reefs across the world. His new research shows that this tiny life is much more diverse than previously understood and may be essential to life of the coral reefs. And, much deeper in the Ocean, researchers estimate that there are over 5000 unnamed species in the world’s largest mineral exploration region, the Clarion-Clipperton Zone. Muriel Rabone, data and sample co-ordinator, and Dr Adrian Glover, merit researcher, both from the Natural History Museum in London, talk to Roland about this region of stunning biodiversity and the hope to protect it.

Presenter: Roland Pease Producer: Ella Hubber Editor: Richard Collings

(Photo: An adult and juvenile California condor. Credit: Loi Nguyen)

A star in the nearby Pinwheel Galaxy has exploded spectacularly into a supernova, dubbed SN 2023ixf. It is the brightest in a decade and it has got astronomers around the world into a frenzy. Science in Action hears from both amateur and professional astronomers alike as they scramble to collect exciting new images and data.

Back on the ground, we hear from the Professor of Climate Change and Earth System Science at the University of Exeter, Tim Lenton about his new paper highlighting how rising global temperatures could push human populations from their homes.

Contributors: Dan Milisavljevic, Assistant Professor in the Department of Physics and Astronomy, Purdue University. Dr Jane Clark, Trustee of the Cardiff Astronomical Society Bronco Oostermeyer, amateur astronomer Raffaella Margutti, Associate Professor in the Department of Physics and Astronomy, University of California, Berkeley Erez Zimmerman, Astrophysics PhD student, Weizmann institute of science Professor Avishay Gal-Yam, Head of Experimental Astrophisics Group, Weizmann institute of science Professor Tim Lenton, Director of the Global Systems Institute and Chair in Climate Change and Earth System Science at the University of Exeter

Presenter: Roland Pease Producer: Ella Hubber

(Image: Supernova SN 2023ixf. Credit: Dr Jane Clark and The Cardiff Astronomical Society)

Over the past few weeks, wildfires have scorched over 1,800 square miles of land across North West America and are still going strong. Dr Mike Flannigan, professor at the Department of Renewable Resources at the University of Alberta, talks to Roland about the weather patterns and record-breaking heat causing the devastating flames.

On the other side of the world, in Zambia, Dr Edgar Simulundu has been finding out why some humans attract mosquitoes more than others, and how we can use this to tackle the malaria epidemic.

Also this week, Professor Novel Chegou, lead investigator at Stellenbosch University Immunology Research Group, has been awarded the 2022 Africa Prize for his innovative method for quickly diagnosing tuberculosis. And we visit the Royal Society for a very different reason. Roland checks in on the “Ukraine's Recovery: Rebuilding with Research” conference, and the discussion to use evidence based approaches for rebuilding after war.

Contributors:

Dr Mike Flannigan, Department of Renewable Resources at the University of Alberta Professor Novel Chegou Novel Chegou, lead investigator at Stellenbosch University Immunology Research Group Dr Edgar Simulundu, Senior Lecturer at the University of Zambia Uliana Avtonomova, Secretary General, Fund of the President of Ukraine for Education, Science, and Sports Olena Sotnyk, lawyer and former member of the Ukrainian parliament Dr Vesna Najdanovic, Energy and Bioproduct Research Institute

Presenter: Roland Pease Producer: Ella Hubber

In 2003, an incredible scientific milestone was achieved as the first human genome completed sequencing. For 20 years, this genome has been used as a reference by researchers for comparison to all other DNA sequences. Now, the Human Pangenome Reference Consortium is addressing the lack of genetic diversity starting with 47 new reference genomes. Members of the consortium, Dr Karen Miga, assistant professor, UC Santa Cruz Genomics Institute and Dr Benedict Paten, associate professor, UC Santa Cruz Genomics Institute, join Roland to discuss the first stages of the project. For the first time the public will have access to thousands of documents from the Royal Society’s historical collections following their digitisation. Science correspondent Vic Gill visits the vaults to see some of these pieces of history first hand. We are also taking a trip 30km above the Earth, to the stratosphere, where Daniel Bowman, principal scientist from Sandia National Laboratories, is using solar powered balloons to listen to the mysterious sounds of our planet. Presenter: Roland Pease Producer: Ella Hubber

(Image Illustration of the globe. Credit: Darryl Leja, NHGRI)

India is at the centre of much of the discussion on this week’s episode of Science In Action.

We hear about how a proposal to scrap Darwinian evolution from Indian secondary schools has led to signatures from thousands of scientists. Dr Vineeta Bal, Researcher at the National University of Immunology, is one of the signatories on a petition against the proposed changes. We spoke to her about why she is against them.

Also in India, a new Sars-Cov-2 variant, named XBBX.16 is being studied by epidemiologists in the country. Dr Rajesh Karyakarte, professor of microbiology at BJ Government Medical College, Pune, India, is behind the study.

Further study of the variant has been looked into by Kei Sato, professor of Systems Virology at the University of Tokyo. Kei has been mapping how new variants could cause us problems, ahead of them doing so.

This kind of forward planning is something praised by Paul Bienaisz, Professor of Virology at The Rockefeller university. We talk to him about how vital this kind of work still is, even if many of us have confined the about the SARS-CoV-2 pandemic to memory.

Lastly, we hear from Dr Usama Kadri, Senior Lecturer in Applied Mathematics at Cardiff University who has looked at how we might be able to use a novel bit of technology of underwater technology (called hydrophones), often used for animal conservation, to be able to detect earthquakes in the deep sea.

Presenter/producer: Roland Pease Producer: Ella Hubber

Khartoum’s National Public Health Laboratory has been caught up in the ongoing conflict in Sudan. Dr Maysoon Dahab and Dr Ayman Ahmed explain the situation and why health labs are often targeted in conflicts.

Virus hunters have used artificial intelligence to discover more than 180,000 new viruses. Professor Eddie Holmes and Dr Mang Shi tell Roland how AI is completely transforming the field of viral discovery.

Experts have forecasted a return to El Niño conditions later this year, which could bring with it extreme weather events. Dr Emily Becker explains how the predictions are made and the global impact of a strong El Niño.

And from future to historical weather – Roland talks to Professor Ed Hawkins about the powerful Storm Ulysses of 1903, and how it can help us better understand storms today.

Presenter: Roland Pease Producer: Roland Pease Assistant Producer: Sophie Ormiston

The pandemic showed Africa at the back of the global queue when it came to vaccines. That should never happen again if plans being debated in Cape Town this week go ahead. Roland talks to Seanette Wilson of South Africa's Biovac.

Also in the programme: life finds a way on plastic floating in the ocean; Greenland rock dust as a global fertiliser; and designing proteins from scratch.

Image Credit: Robert Bonet/NurPhoto via Getty Images

Presenter: Roland Pease Producer: Roland Pease Assistant Producer: Sophie Ormiston

H5N1, a highly pathogenic avian flu is racing across the world, and has infected multiple species, including wild and farmed birds, and mammals from cats to sea lions. What can be done to control it? Roland Pease talks to global experts about the dangers to animal and human health, and about the measures to bring the outbreak under control.

Producer: Roland Pease Assistant producer: Sophie Ormiston

(Photo: A government worker examines chicks for signs of bird flu infection at a poultry farm in Darul Imarah in Indonesia's Aceh province. Credit: Chaideer Mahyuddin)

Chasing tornados in the American mid-West – scientists are trying to learn the maximum from the tornado outbreaks currently in America. Professor Karen Kosiba calls us from a radar truck studying the storms, and Professor John Allen explains the energy powering them. From the weather of today to the skies of 800 years ago... Dr Sébastien Guillet reveals how lunar observations by medieval monks are helping untangle the connection between historic eruptions and climate. Finally, we go back even further in time to the Bronze Age with Professor Elisa Guerra-Doce – to find out what drugs our ancestors were into.

Image credit: Getty Images / Michael B. Thomas Producer: Roland Pease Assistant Producer: Sophie Ormiston

We look at a gene editing breakthrough, a new technique to correct genetic errors in sick patients. Roland speaks to Professor David Liu to learn about the base editing technology.

Also, we look into the complex causes of last year's post-pandemic spike in child hepatitis. Professor Judy Breuer and her colleagues may have found an explanation behind the unexpected outbreak.

And the James Webb Space Telescope continues to seek out the secrets of our universe. Professor Beth Biller and Dr Elsa Ducrot have the details on the atmospheres of two very distant, and very different, exoplanets.

Plus, how to get sober – for mice. Professor Steven Kliewer explains how certain mammals have evolved to deal with the intoxicating effects of ethanol.

Producer: Roland Pease Assistant Producer: Sophie Ormiston

(Image: Genetic engineering 3D rendered conceptual image. Credit: Getty Images)

DNA has revealed potential animal COVID carriers at the Wuhan market, but what does that tell us about the start of the pandemic? Roland talks to two of the experts behind the new analysis: Dr Florence Débarre and Professor Eddie Holmes.

Also, we look into Europe’s grand new space ambitions. ESA director general Josef Aschbacher gives Roland the details of the space agency’s out-of-this-world plans.

And Beethoven's last DNA: a hairy story of his family and genetic afflictions. Dr Tristan Begg shares how the composer’s tresses unlocked new information about his life and death.

Image credit: Eddie Holmes

Producer: Roland Pease Assistant producer: Sophie Ormiston

34 days after it first formed at the far end of the Indian Ocean, record-breaking Cyclone Freddy made a repeat landfall on Mozambique as well as passing over Malawi, causing extensive damage and loss of life. Climate scientists Liz Stephens and Izidine Pinto join Roland to give an update on the destruction and explain how Cyclone Freddy kept going for an exceptionally long time.

At the Third International Human Genome Summit in London last week, Professor Katsuhiko Hayashi announced he had created baby mice from eggs formed by male mouse cells. Dr Nitzan Gonen explains the underlying science, whilst Professor Hank Greely discusses the ethics and future prospects.

And from one rodent story to another, SARS-CoV-2 has been detected in brown rats scurrying around New York sewers. Dr Thomas DeLiberto from the US Department of Agriculture gives Roland the details.

Image credit: Jack McBrams/Getty Images

Producer: Roland Pease Assistant Producer: Sophie Ormiston

Human Genome Editing: The team meet experts at the Human Genome Editing Summit in London, seeking to cure genetic disease and ensure that it's safe and available to all. Roland Pease hears from Victoria Gray, the first person to be cured of the debilitating and life-shortening disease sickle cell anaemia by gene editing, and from the scientists making it possible. Also, the prospect of work to attempt gene rescue in fetuses before they are born. But the technology is expensive and complex – the question troubling the participants is to ensure people across the world can benefit from it, not just the rich and privileged. And what are the limitations of gene editing? Can it be made more effective, safer? And what of gene edits that will be inherited by future generations?

The long rains of East Africa are forecast to fail again, for the third year running, precipitating a food crisis affecting millions. Science In Action explores the science of the drought, hears about new methods improving forecasts, and what is unusual about the region that makes it so vulnerable.

When we think of helium, for many of us balloons and squeaky voices come to mind. But the noble gas is critical for many aspects of modern life – and we’re facing a global shortage. Dr Annie Cheng and her colleagues at the University of Oxford are attempting to solve this by creating a model that has the potential to locate previously untapped reservoirs.

Image by Gerald Anderson/Anadolu Agency via Getty Images

Producer: Roland Pease Assistant Producer: Sophie Ormiston

Cyclone Freddy has made landfall on Madagascar, leaving destruction in its wake. At the time this edition of Science In Action is going to air, Freddy is on course to reach Mozambique and South Africa. Freddy, which has been gaining strength since it originally formed on the 30th of January, is the most powerful southern hemisphere cyclone on record. Professor Francois Engelbrecht provides the science behind the storm system.

In the centre of our galaxy, an enormous cloud is heading towards the Milky Way’s supermassive black hole. Dr Anna Ciurlo tells us that this is a unique opportunity to study the influence of the black hole on the cloud’s shape and properties.

We’ve heard a lot about balloons floating above Earth recently… but what about sending balloons to Venus? That’s exactly what Dr Siddharth Krishnamoorthy is proposing in order to study Venus’s seismic activity. Recorders on a “floatilla” above the planet’s surface could listen into Venus-quakes and reveal Venus’s mysterious past.

And closer to home, scientists have discovered a new layer in the Earth’s core. We journey into the very centre of the Earth with Professor Hrvoje Tkalčić, who tells Roland what the innermost inner core can teach us about our planet’s past.

Image: NASA Earth Observatory image by Lauren Dauphin, using VIIRS data from NASA EOSDIS LANCE, GIBS/Worldview, and the Joint Polar Satellite System (JPSS).

Producer: Roland Pease Assistant Producer: Sophie Ormiston

In the decade since the genome editing capabilities of CRISPR-Cas9 emerged, research into novel medicines has boomed – but alongside progress comes new ethical considerations. Controversy erupted in 2018, when Chinese scientist He Jiankui created the first babies with edited genomes. After leaving prison last year, he’s now back in the lab trying to raise support for new research but refuses to discuss the ethical implications of his work. Dr Joy Zhang recently arranged a bioethics seminar and invited He Jiankui, it was the first time he’d agreed to engage with a global cohort of CRISPR scientists since returning to his research.

Going back in time from cutting-edge to ancient technology, some of the oldest stone tools ever used by human ancestors have been unearthed at a fossil site in Kenya. Professor Tom Plummer talks us through the findings and how important the tools were in our evolution.

And we immerse ourselves in the mysterious sounds of the Arctic and Antarctic, from singing ice to the man-made noises of oil and gas drilling. These dramatic soundscapes, created for the Polar Soundscapes project, showcase just how busy our oceans are. Dr Geraint Rhys Whittaker, composer and project lead, believes a novel approach may be required to prompt climate action.

Image Credit: Anthony Wallace

Presenter: Roland Pease Producer: Harrison Lewis Assistant Producer: Sophie Ormiston

In the early hours of Monday, a powerful earthquake hit Kahramanmaras in Turkey. Nine hours later another struck. When this edition of Science in Action first aired, 19,000 people were reported to have died, but that number was expected to rise.

Back in 2016, Professor Asli Garagon and her colleagues accurately predicted that an earthquake of this size was coming. Using GPS, they were monitoring the East Anatolian fault to calculate energy building between the plates. With such accurate insight could Turkey have been better prepared?

Ross Stein, seismologist and founder of Temblor, a Californian consultancy that specialises in assessing hazard risk, estimates the plates moved at 5,000 mph. The movement of the plates may have built up pressure in other parts of the country.

And finally, Tiziana Rossetto, a civil engineer at University College London, knows better than most that earthquakes do not kill, buildings do. She tells Roland how the combination of earthquakes and subsequent aftershocks appear to have even destroyed buildings that were purposely built to withstand them.

Presenter: Roland Pease Producer: Harrison Lewis Assistant producer: Sophie Ormiston

Image: Aftermath of the deadly earthquake in Gaziantep Credit: REUTERS/Dilara Senkaya

Pull on an extra layer and stay toasty whilst Science in Action braces for a deep freeze. Whilst we know plenty about the ice on the Earth’s poles, Roland is on a chilling journey to see what can be found in deep space. Professor Christoph Salzmann and Professor Andrea Sella at University College London have produced a new phase of ice. Roland heads to the laboratory to see how the usual crystalline ice, found in ice cubes and icebergs, can be broken down and arranged into a new structure. The James Webb Space Telescope has detected the coldest ices to date, deep within a molecular cloud in outer space. Professor Melissa McClure describes how these clouds harbour a variety of different molecules potentially capable of forming the basic building blocks for life. From the edges of the universe to something a little closer to home, Professor Geoff Collins and colleagues have discovered odd tectonic plate activity on icy Europa, one of Jupiter’s moons. And a theory for the origin of life that may surprise you. Professor Philipp Holliger is trying to uncover whether ice played a role in our creation, acting as a medium capable of concentrating molecules and promoting the chemical reactions required for the generation of RNA, essential for cell protein production. Presenter: Roland Pease Producer: Harrison Lewis Assistant Producer: Sophie Ormiston

(Photo: Chunk of ice. Credit: Getty Images)

An outbreak of pathogenic bird flu, H5N1, in a Spanish mink farm could be a cause for concern. Some experts fear the virus may now spill over to other mammals without strict surveillance. Marion Koopmans, professor of virology at Erasmus Medical Centre, talks Roland through the potential risks. India’s caste system affects all aspects of society, but how does the hierarchy influence representation of marginalised groups in academia? Science journalist Ankur Paliwal believes that, despite efforts to combat discrimination, not enough is being done, and he has the data to prove it. Imagine a robot... Is it hard, metallic and humanoid? Professor Carmel Majidi from Carnegie Mellon University and his colleagues are thinking outside the robotics box. Their new material, magnetic in nature, can shift between solid and liquid states. It’s even capable of breaking out of robotic jail... And how do echidnas – spiny, long-nosed, egg-laying mammals – manage to stay cool during the hot Australian summers? Image credit: Ole Jensen/Getty Presenter: Roland Pease Producer: Harrison Lewis Assistant Producer: Sophie Ormiston

Climate researcher, Rose Abramoff took to the stage at the American Geophysical Union (AGU) fall meetings, not as a guest speaker but in protest. Whilst her demonstration only lasted 15 seconds, she found her employment terminated from Oak Ridge National Laboratory and research stripped from the AGU programme. She was attempting to persuade other climate scientists to ‘get out of the lab and into the street’. Whilst Rose’s protest hit the headlines in the media, potentially less attention was paid to the session that was taking place at the conference, hosted by Mika Tosca, climate scientist-turn-artist, Associate Professor of Liberal Arts at the School of the Art Institute of Chicago. Roland brings the two together to discuss the event and how climate scientists should approach activism.

Although there is no one solution to the climate crisis, Roland loves a brainstorm on Science in Action. Climate activist Stuart Capstick, a Cardiff University psychologist specialising in public attitudes to environmental issues and environmental scientist Robert Young from Western Carolina University take the conversation one step further. Questioning how public perceptions of scientists change when they take evasive action and protest.

And finally, we usually hear of seismology reports coming from dense, urban areas prone to earthquakes, delicately perched atop of tectonic plates. But this week, Roland speaks to Professor of Geophysics Zhongwen Zhan from the California Institute of Technology, who’s collecting data from a very unusual place...

Image credit: SOPA Images

Presenter: Roland Pease Producer: Harrison Lewis

Flood warnings in parts of California have seen some of the state’s best known celebrities flee their homes. The current weather conditions are in part the result of ‘Atmospheric rivers’ – literally fast flowing rivers of water vapor in the atmosphere. Marty Ralph from the Scripps Institute has been studying this phenomenon for years, he explains what atmospheric rivers are, and tells us how a greater understanding of the phenomenon is now informing weather forecasting and evacuation plans.

Over the past year several million people have fled Ukraine, amongst them many scientists. Nataliya Shulga from the Ukraine Science Club is working on a wide ranging initiative to attract them back. She tells us of plans not just to reconstruct Ukrainian science facilities after the war, but to offer a philosophical change which breaks with the Soviet past - a more global, collaborative environment for scientists returning to the Ukraine.

Last December the Afghan Taliban banned women from attending university, its just one of the many moves denying education to women since the Taliban returned to power. Particle physicist Kate Shaw had been working with Afghan physicists in the years before the Taliban’s comeback, she is now developing an initiative with scientists and institutions around the world to offer places to Afghan women keen to study physics. She says institutions and individuals who may be able to help should contact Physics without Frontiers at the International Centre for Theoretical Physics.

And Gibbons sing with synchronicity, a new study led by Teresa Raimondi, from the University of Turin shows the ability of couples to chorus together to be rather human like.

Image Credit: Josh Edelson

Presenter: Roland Pease Producer: Julian Siddle

We’re taking a look back at the January 2022 eruption of Hunga Tonga-Hunga Ha’apai, which literally sent shockwaves around the world. One year on, and we’re still uncovering what made the volcano so powerful, as well as unpacking its long lasting impacts.

Roland is joined by Professor Shane Cronin from the University of Auckland and Dr Marta Ribó from the Auckland University of Technology to share their findings from their latest trip to survey the volcano.

The impacts of the eruption weren’t just felt on Earth – they also reached all the way to space. Physicist Claire Gasque from the University of California, Berkeley, has been analysing how the eruption affected space weather.

Amongst all the material ejected by Hunga Tonga was a huge amount of water. The massive water vapour cloud is still present in our atmosphere, as Professor Simon Carn from the Michigan Technological University tells us.

The volcano also triggered tsunamis worldwide. Disaster sociologist Dr Sara McBride from the US Geological Survey has been using video footage of the event to analyse how people responded and how we can better prepare for future eruptions.

Image Credit: Tonga Geological Services

Presenter: Roland Pease Producer: Sophie Ormiston

Nasa's James Webb Space Telescope has produced amazing images, and amazing science, in its first five months. Roland Pease hears from one of the leading astronomers on the JWST programme, Dr Heidi Hammel, as well as other experts on what they are already learning about the first galaxies in the Universe, the birthplaces of stars, the strange behaviour of some other stars, and the first view of Neptune's rings in over 30 years.

Producer: Roland Pease Assistant producer: Sophie Ormiston

Image: An image from the James Webb Space Telescope (Credit: Nasa via PA)

Mosquito pesticide failing - prevention of dengue fever and other diseases at risk. Dangerous bird flu evolving fast - researchers are learning why bird flu is persisting and spreading fast round the world, and assess the threat to humans. Drilling for ancient ice in the Antarctic - Roland talks to one of the team drilling kilometres into an ancient, frozen record of past climate, Martian rock store opens - NASA's Mars Perseverance rover is stashing rock samples future missions could bring back to Earth.

Image credit: Shinji Kasai

Producer: Roland Pease Assistant Producer: Sophie Ormiston